Human cells treated with trifluoperazine (TFP) or K252a prior to and/or during priming with human interferon-α (HuIFN-α) produce significantly more IFN on induction with poly(rI) · poly(rC) than primed cells in the absence of the drug. Results suggest that calmodulin/protein kinase activity may be involved in priming activity of HuIFN-α.
|Number of pages||4|
|Journal||Journal of Interferon Research|
|Publication status||Published - 1990|
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