Risk of retinal vein occlusion in patients with psoriasis

Yung Chang Yen, Shih Feng Weng, Feng Jie Lai, Yong-Song Lin

Research output: Contribution to journalArticle

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Abstract

Purpose: To investigate the risk of developing retinal vein occlusion (RVO) in patients with psoriasis. Methods: In this retrospective population-based cohort study, 30,198 patients with psoriasis (Psoriasis (+) group) and 30,198 controls without psoriasis (Psoriasis (-) group) between 2001 and 2006 from the Taiwan National Health Insurance Research Database were selected. Results: The incidence of RVO was 1.46 times higher in the Psoriasis (+) group than in the Psoriasis (-) group (3.61 vs. 2.47/10,000 person-years) (adjusted hazard ratio 1.50; 95% confidence interval 1.07-2.10) calculated using Cox proportional hazard regression. Age was an independent risk factor for RVO (adjusted hazard ratio: 11.9 for patients 65 years or older vs. 1.00 for those 0-49 years old). In the 65 years or older Psoriasis (+) group, the incidence of developing RVO was 1.97 times higher (95% confidence interval 1.19-3.26) than in the 65 years or older Psoriasis (-) group. In Psoriasis (+) women, the incidence of developing RVO was 1.82 times higher (95% 1.05-3.14) than in Psoriasis (-) women. For the subgroup with comorbid hypertension, the incidence of developing RVO was 2.07 times higher (95% confidence interval 1.22-3.50) in the Psoriasis (+) group than in the Psoriasis (-) group. Conclusion: Psoriasis was significantly associated with a higher risk of developing RVO.
Original languageEnglish
Pages (from-to)1786-1794
Number of pages9
JournalRetina
Volume35
Issue number9
DOIs
Publication statusPublished - Jan 1 2015

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Retinal Vein Occlusion
Psoriasis
Incidence
Confidence Intervals
National Health Programs
Taiwan

Keywords

  • autoimmune disease

Cite this

Yen, Y. C., Weng, S. F., Lai, F. J., & Lin, Y-S. (2015). Risk of retinal vein occlusion in patients with psoriasis. Retina, 35(9), 1786-1794. https://doi.org/10.1097/IAE.0000000000000536

Risk of retinal vein occlusion in patients with psoriasis. / Yen, Yung Chang; Weng, Shih Feng; Lai, Feng Jie; Lin, Yong-Song.

In: Retina, Vol. 35, No. 9, 01.01.2015, p. 1786-1794.

Research output: Contribution to journalArticle

Yen, YC, Weng, SF, Lai, FJ & Lin, Y-S 2015, 'Risk of retinal vein occlusion in patients with psoriasis', Retina, vol. 35, no. 9, pp. 1786-1794. https://doi.org/10.1097/IAE.0000000000000536
Yen, Yung Chang ; Weng, Shih Feng ; Lai, Feng Jie ; Lin, Yong-Song. / Risk of retinal vein occlusion in patients with psoriasis. In: Retina. 2015 ; Vol. 35, No. 9. pp. 1786-1794.
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