Risk of non-melanoma skin cancer in patients with chronic kidney disease and its relationship to uraemic pruritus

Chia Chen Wang, Chao Hsiun Tang, Siao Yuan Huang, Kuan Chih Huang, Yuh Mou Sue

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

This study investigated the risk of non-melanoma skin cancer (NMSC) in pre-dialysis patients with chronic kidney disease (CKD) and explored associated risk factors. A population-based cohort of 1,515,858 Taiwanese CKD patients was included. The standardized incidence ratio (SIR) for incident NMSC was determined. Compared with the general population, a 1.14- fold risk of NMSC was found in the CKD cohort. NMSC risk was significant in patients with pre-dialysis stage 5 CKD and anaemia (1.48-fold), and in those with uraemic pruritus after long-term antihistamine treatment (1.38-fold). A higher SIR for NMSC was found in younger patients with CKD (age < 70 years, 1.34-fold; age 20–39 years, 1.63-fold), stage 5 CKD with anaemia (age < 70 years, 2.09-fold), and uraemic pruritus (age <70 years, 2.22-fold). Pre-dialysis patients with CKD are at higher risk of NMSC, especially those with advanced-stage CKD, and those with uraemic pruritus.

Original languageEnglish
Pages (from-to)1230-1234
Number of pages5
JournalActa Dermato-Venereologica
Volume97
Issue number10
DOIs
Publication statusPublished - Nov 1 2017

Fingerprint

Skin Neoplasms
Pruritus
Chronic Renal Insufficiency
Dialysis
Anemia
Histamine Antagonists
Incidence
Population

Keywords

  • Chronic kidney disease
  • Epidemiology
  • Non-melanoma skin cancer
  • Uraemic pruritus

ASJC Scopus subject areas

  • Dermatology

Cite this

Risk of non-melanoma skin cancer in patients with chronic kidney disease and its relationship to uraemic pruritus. / Wang, Chia Chen; Tang, Chao Hsiun; Huang, Siao Yuan; Huang, Kuan Chih; Sue, Yuh Mou.

In: Acta Dermato-Venereologica, Vol. 97, No. 10, 01.11.2017, p. 1230-1234.

Research output: Contribution to journalArticle

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