Risk of hand syndromes in patients with diabetes mellitus: A population-based cohort study in Taiwan

Lu Hsuan Chen, Chung Yi Li, Li Chieh Kuo, Liang Yi Wang, Ken N. Kuo, I. Ming Jou, Wen Hsuan Hou

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The aim of this study was to assess the overall and causespecific incidences of diabetic hand syndromes (DHS) in patients with diabetes mellitus (DM) by using age and sex stratifications. The DM and control cohorts comprised 606,152 patients with DM and 609,970 age-and sex-matched subjects, respectively, who were followed up from 2000 to 2008. We estimated the incidence densities (IDs) of overall and cause-specific DHS, namely carpal tunnel syndrome (CTS), stenosing flexor tenosynovitis (SFT), limited joint mobility (LJM), and Dupuytren disease (DD), and calculated the hazard ratios (HRs) of DHS in relation to DM by using a Cox proportional hazards model with adjustment for potential confounders. Over a 9-year period, 51,207 patients with DM (8.45%) and 39,153 matched controls (6.42%) sought ambulatory care visits for various DHS, with an ID of 117.7 and 80.7 per 10,000 person-years, respectively. The highest cause-specific ID was observed for CTS, followed by SFT, LJM, and DD, regardless of the diabetic status. After adjustment for potential confounders, patients with DM had a significantly high HR of overall DHS (1.51, 95% confidence interval [CI]=1.48-1.53). Men and women aged

Original languageEnglish
Article numbere1575
JournalMedicine (United States)
Volume94
Issue number41
DOIs
Publication statusPublished - 2015

ASJC Scopus subject areas

  • Medicine(all)

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