Abstract

The rates of Cesarean delivery (C-section) have risen to >30 % in numerous countries. Increased risk of autism has been shown in neonates delivered by C-section. This study examined the incidence of autism in neonates delivered vaginally, by C-section with regional anesthesia (RA), and by C-section with general anesthesia (GA) to evaluate the risk of autism associated with C-section and obstetric anesthesia. During a mean follow-up of 4.3 years, the incidence of autism was higher in neonates delivered by C-section with GA than in neonates delivered vaginally, with an adjusted risk of 1.52 (95 % confidence interval 1.18–1.94). However, the adjusted risk of autism in neonates delivered by C-section with RA and in neonates delivered vaginally was nonsignificantly different.

Original languageEnglish
Pages (from-to)932-942
Number of pages11
JournalJournal of Autism and Developmental Disorders
Volume45
Issue number4
DOIs
Publication statusPublished - 2015

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Keywords

  • Autism
  • Cesarean delivery
  • Obstetric anesthesia
  • Population-based birth cohort

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Medicine(all)

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