Risk of accidental injuries amongst Parkinson disease patients

Han-Cheng Wang, C. C. Lin, C. I. Lau, A. Chang, F. C. Sung, C. H. Kao

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background and purpose: To investigate the spectrum and risks of accidental injuries (AIs) amongst Parkinson disease (PD) patients. Methods: The participants comprised PD patients aged 50 years and older who were initially diagnosed between 2000 and 2009, and a comparison group of non-PD patients. The incidence rates of accidental injury types amongst PD and non-PD patients were calculated; hazard ratios were calculated and adjusted for comorbidities, using 95% confidence intervals (CIs) of developing such outcomes in PD patients. Results: In total, 4046 PD patients and 16 184 non-PD patients were followed over time. The PD patients demonstrated the following incidence rates and hazard ratios in comparison to the control cohort for accidental injuries: all injuries, 19.78 per 100 person-years (100 PYs), adjusted hazard ratio (HR) 1.30 (95% CI 1.24-1.36); head injury, 2.95 per 100 PYs, HR 1.88 (95% CI 1.64-2.15); bone fracture and dislocation, 4.61 per 100 PYs, HR 1.39 (95% CI 1.25-1.54); burns, 0.66 per 100 PYs, HR 1.01 (95% CI 0.78-1.32); injury to spinal cord, plexus and nerves, 0.15 per 100 PYs, HR 1.25 (95% CI 0.72-2.17); superficial injuries and contusions, 11.41 per 100 PYs, HR 1.20 (95% CI 1.12-1.27). The injury risk for the 69-79 years age group in PD compared with controls of the same age (HR 1.38) was significantly higher compared with that of the 50-69 age groups in PD and controls (HR 1.16). Conclusions: Parkinson disease patients demonstrate a significantly elevated risk of developing all accidental injury types except burn injuries and injuries to spinal cord, plexus and nerves, compared with age-matched controls. The risk increases as age increases.

Original languageEnglish
Pages (from-to)907-913
Number of pages7
JournalEuropean Journal of Neurology
Volume21
Issue number6
DOIs
Publication statusPublished - 2014

Fingerprint

Parkinson Disease
Wounds and Injuries
Confidence Intervals
Spinal Nerves
Spinal Cord
Age Groups
Safety Management
Contusions
Bone Fractures
Incidence
Burns
Craniocerebral Trauma
Comorbidity

Keywords

  • Accidental injuries
  • National Health Insurance Research Database (NHIRD)
  • Parkinson disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Medicine(all)

Cite this

Wang, H-C., Lin, C. C., Lau, C. I., Chang, A., Sung, F. C., & Kao, C. H. (2014). Risk of accidental injuries amongst Parkinson disease patients. European Journal of Neurology, 21(6), 907-913. https://doi.org/10.1111/ene.12410

Risk of accidental injuries amongst Parkinson disease patients. / Wang, Han-Cheng; Lin, C. C.; Lau, C. I.; Chang, A.; Sung, F. C.; Kao, C. H.

In: European Journal of Neurology, Vol. 21, No. 6, 2014, p. 907-913.

Research output: Contribution to journalArticle

Wang, H-C, Lin, CC, Lau, CI, Chang, A, Sung, FC & Kao, CH 2014, 'Risk of accidental injuries amongst Parkinson disease patients', European Journal of Neurology, vol. 21, no. 6, pp. 907-913. https://doi.org/10.1111/ene.12410
Wang, Han-Cheng ; Lin, C. C. ; Lau, C. I. ; Chang, A. ; Sung, F. C. ; Kao, C. H. / Risk of accidental injuries amongst Parkinson disease patients. In: European Journal of Neurology. 2014 ; Vol. 21, No. 6. pp. 907-913.
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