Risk factors of tuberculosis infection among HIV/AIDS patients in Burkina Faso

Ziemlé Clément Méda, Issiaka Sombié, Olivier W.C. Sanon, Daouda Maré, Donald E. Morisky, Yi Ming Arthur Chen

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Tuberculosis (TB) and HIV coinfection is the leading cause of mortality among TB patients and people living with HIV/AIDS (PLWHAs). There is still a need to look for cognitive and behavioral determinants of TB among PLWHAs. This study aims at identifying risk factors of TB infection among PLWHAs in Burkina Faso. A cross-sectional study design and consecutive recruitment method were employed. Adult patients attending TB hospitals or HIV clinics were recruited in two main regions (Hauts-Bassins and Centre) of Burkina Faso from August to October 2010. Stepwise logistic regression models were used for statistical analysis. In total, 734 PLWHAs, including 181 (24.7%) coinfected with TB, participated in this study. Of the latter, 53.4% were from the Hauts-Bassins region and 46.6% from the Centre region. Adjusted TB risk factors among PLWHAs were urban setting, TB history, higher number of persons living in the household, and poor geographic access to care. Moreover adjusted TB risk factors among PLWHAs consisted of CD4 cell counts below 200/μl, a history of sexually transmissible infections, and a past or present history of pulmonary asthma. In addition, lack of education and arterial hypertension were additional risk factors in the Hauts-Bassins region; for PLWHAs in the Centre region, male gender, jobs not in the private and public sector, and past or present history of cardiovascular disease were additional risk factors for TB. Common and different risk factors for TB were identified for PLWHAs in the Hauts-Bassins and Centre regions. This information will be incorporated into the HIV/TB control programs in the future.

Original languageEnglish
Pages (from-to)1045-1055
Number of pages11
JournalAIDS Research and Human Retroviruses
Volume29
Issue number7
DOIs
Publication statusPublished - Jul 1 2013
Externally publishedYes

Fingerprint

Burkina Faso
HIV Infections
Acquired Immunodeficiency Syndrome
Tuberculosis
HIV
Logistic Models
Chronic Disease Hospitals
Private Sector
Public Sector
CD4 Lymphocyte Count
Infection
Coinfection
Cardiovascular Diseases
Asthma
Cross-Sectional Studies

ASJC Scopus subject areas

  • Immunology
  • Virology
  • Infectious Diseases

Cite this

Risk factors of tuberculosis infection among HIV/AIDS patients in Burkina Faso. / Méda, Ziemlé Clément; Sombié, Issiaka; Sanon, Olivier W.C.; Maré, Daouda; Morisky, Donald E.; Chen, Yi Ming Arthur.

In: AIDS Research and Human Retroviruses, Vol. 29, No. 7, 01.07.2013, p. 1045-1055.

Research output: Contribution to journalArticle

Méda, Ziemlé Clément ; Sombié, Issiaka ; Sanon, Olivier W.C. ; Maré, Daouda ; Morisky, Donald E. ; Chen, Yi Ming Arthur. / Risk factors of tuberculosis infection among HIV/AIDS patients in Burkina Faso. In: AIDS Research and Human Retroviruses. 2013 ; Vol. 29, No. 7. pp. 1045-1055.
@article{b02d511afd4f4269b7711adbb67bd715,
title = "Risk factors of tuberculosis infection among HIV/AIDS patients in Burkina Faso",
abstract = "Tuberculosis (TB) and HIV coinfection is the leading cause of mortality among TB patients and people living with HIV/AIDS (PLWHAs). There is still a need to look for cognitive and behavioral determinants of TB among PLWHAs. This study aims at identifying risk factors of TB infection among PLWHAs in Burkina Faso. A cross-sectional study design and consecutive recruitment method were employed. Adult patients attending TB hospitals or HIV clinics were recruited in two main regions (Hauts-Bassins and Centre) of Burkina Faso from August to October 2010. Stepwise logistic regression models were used for statistical analysis. In total, 734 PLWHAs, including 181 (24.7{\%}) coinfected with TB, participated in this study. Of the latter, 53.4{\%} were from the Hauts-Bassins region and 46.6{\%} from the Centre region. Adjusted TB risk factors among PLWHAs were urban setting, TB history, higher number of persons living in the household, and poor geographic access to care. Moreover adjusted TB risk factors among PLWHAs consisted of CD4 cell counts below 200/μl, a history of sexually transmissible infections, and a past or present history of pulmonary asthma. In addition, lack of education and arterial hypertension were additional risk factors in the Hauts-Bassins region; for PLWHAs in the Centre region, male gender, jobs not in the private and public sector, and past or present history of cardiovascular disease were additional risk factors for TB. Common and different risk factors for TB were identified for PLWHAs in the Hauts-Bassins and Centre regions. This information will be incorporated into the HIV/TB control programs in the future.",
author = "M{\'e}da, {Zieml{\'e} Cl{\'e}ment} and Issiaka Sombi{\'e} and Sanon, {Olivier W.C.} and Daouda Mar{\'e} and Morisky, {Donald E.} and Chen, {Yi Ming Arthur}",
year = "2013",
month = "7",
day = "1",
doi = "10.1089/aid.2012.0239",
language = "English",
volume = "29",
pages = "1045--1055",
journal = "AIDS Research and Human Retroviruses",
issn = "0889-2229",
publisher = "Mary Ann Liebert Inc.",
number = "7",

}

TY - JOUR

T1 - Risk factors of tuberculosis infection among HIV/AIDS patients in Burkina Faso

AU - Méda, Ziemlé Clément

AU - Sombié, Issiaka

AU - Sanon, Olivier W.C.

AU - Maré, Daouda

AU - Morisky, Donald E.

AU - Chen, Yi Ming Arthur

PY - 2013/7/1

Y1 - 2013/7/1

N2 - Tuberculosis (TB) and HIV coinfection is the leading cause of mortality among TB patients and people living with HIV/AIDS (PLWHAs). There is still a need to look for cognitive and behavioral determinants of TB among PLWHAs. This study aims at identifying risk factors of TB infection among PLWHAs in Burkina Faso. A cross-sectional study design and consecutive recruitment method were employed. Adult patients attending TB hospitals or HIV clinics were recruited in two main regions (Hauts-Bassins and Centre) of Burkina Faso from August to October 2010. Stepwise logistic regression models were used for statistical analysis. In total, 734 PLWHAs, including 181 (24.7%) coinfected with TB, participated in this study. Of the latter, 53.4% were from the Hauts-Bassins region and 46.6% from the Centre region. Adjusted TB risk factors among PLWHAs were urban setting, TB history, higher number of persons living in the household, and poor geographic access to care. Moreover adjusted TB risk factors among PLWHAs consisted of CD4 cell counts below 200/μl, a history of sexually transmissible infections, and a past or present history of pulmonary asthma. In addition, lack of education and arterial hypertension were additional risk factors in the Hauts-Bassins region; for PLWHAs in the Centre region, male gender, jobs not in the private and public sector, and past or present history of cardiovascular disease were additional risk factors for TB. Common and different risk factors for TB were identified for PLWHAs in the Hauts-Bassins and Centre regions. This information will be incorporated into the HIV/TB control programs in the future.

AB - Tuberculosis (TB) and HIV coinfection is the leading cause of mortality among TB patients and people living with HIV/AIDS (PLWHAs). There is still a need to look for cognitive and behavioral determinants of TB among PLWHAs. This study aims at identifying risk factors of TB infection among PLWHAs in Burkina Faso. A cross-sectional study design and consecutive recruitment method were employed. Adult patients attending TB hospitals or HIV clinics were recruited in two main regions (Hauts-Bassins and Centre) of Burkina Faso from August to October 2010. Stepwise logistic regression models were used for statistical analysis. In total, 734 PLWHAs, including 181 (24.7%) coinfected with TB, participated in this study. Of the latter, 53.4% were from the Hauts-Bassins region and 46.6% from the Centre region. Adjusted TB risk factors among PLWHAs were urban setting, TB history, higher number of persons living in the household, and poor geographic access to care. Moreover adjusted TB risk factors among PLWHAs consisted of CD4 cell counts below 200/μl, a history of sexually transmissible infections, and a past or present history of pulmonary asthma. In addition, lack of education and arterial hypertension were additional risk factors in the Hauts-Bassins region; for PLWHAs in the Centre region, male gender, jobs not in the private and public sector, and past or present history of cardiovascular disease were additional risk factors for TB. Common and different risk factors for TB were identified for PLWHAs in the Hauts-Bassins and Centre regions. This information will be incorporated into the HIV/TB control programs in the future.

UR - http://www.scopus.com/inward/record.url?scp=84879181900&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879181900&partnerID=8YFLogxK

U2 - 10.1089/aid.2012.0239

DO - 10.1089/aid.2012.0239

M3 - Article

C2 - 23517547

AN - SCOPUS:84879181900

VL - 29

SP - 1045

EP - 1055

JO - AIDS Research and Human Retroviruses

JF - AIDS Research and Human Retroviruses

SN - 0889-2229

IS - 7

ER -