Risk factors of depression after prolonged low-dose rate environmental radiation exposure

Pimei Nancy Yen, I. Feng Lin, Wushou Peter Chang, Jung Der Wang, Tien Chun Chang, Kuan Liang Kuo, Jing Shiang Hwang, I. Chao Liu, Yi Ting Chen, Chen Chang Yang

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Purpose: More than 10,000 Taiwanese people were exposed to excessive protracted low-dose rate radiation from contaminated reinforcement bars, which were installed in buildings before 1992. This study was conducted to assess the prevalence of depression amongst the exposed and identify related determinants now that more than two decades have passed since this population was informed of their exposure to radiation. Materials and methods: We used the Beck depression inventory (BDI)-1A questionnaire to survey 2143 eligible people during their annual physical examinations between March 2009 and December 2009. In total, 1621 people participated in the survey. We employed multivariate logistic regression models with generalized estimating equations method to identify the determinants of depression. Results: The prevalence of depression (BDI-IA score ≥ 12) was 18.7%. Those who exhibited higher cumulative exposure [adjusted odds ratio (OR): 1.46, 95% confidence interval (CI): 1.02-2.07] and a previous history of depression (adjusted OR: 2.49, 95% CI: 1.36-4.58) were significantly associated with the risk of depression, whereas education level was inversely related to depression (adjusted OR: 0.71, 95% CI: 0.50-0.99). Conclusion: Long-term, low-dose rate radiation exposure early in life might cause subsequent psychological stress and an increased risk of depression decades later.

Original languageEnglish
Pages (from-to)859-866
Number of pages8
JournalInternational Journal of Radiation Biology
Volume90
Issue number10
DOIs
Publication statusPublished - Oct 1 2014
Externally publishedYes

Fingerprint

Environmental Exposure
Depression
Odds Ratio
Confidence Intervals
Logistic Models
Radiation Exposure
Equipment and Supplies
Psychological Stress
Physical Examination
Radiation
Education

Keywords

  • Epidemiology
  • health surveillance
  • ionizing radiation
  • low-dose effects
  • mental health
  • stress

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Medicine(all)

Cite this

Yen, P. N., Lin, I. F., Chang, W. P., Wang, J. D., Chang, T. C., Kuo, K. L., ... Yang, C. C. (2014). Risk factors of depression after prolonged low-dose rate environmental radiation exposure. International Journal of Radiation Biology, 90(10), 859-866. https://doi.org/10.3109/09553002.2014.916830

Risk factors of depression after prolonged low-dose rate environmental radiation exposure. / Yen, Pimei Nancy; Lin, I. Feng; Chang, Wushou Peter; Wang, Jung Der; Chang, Tien Chun; Kuo, Kuan Liang; Hwang, Jing Shiang; Liu, I. Chao; Chen, Yi Ting; Yang, Chen Chang.

In: International Journal of Radiation Biology, Vol. 90, No. 10, 01.10.2014, p. 859-866.

Research output: Contribution to journalArticle

Yen, PN, Lin, IF, Chang, WP, Wang, JD, Chang, TC, Kuo, KL, Hwang, JS, Liu, IC, Chen, YT & Yang, CC 2014, 'Risk factors of depression after prolonged low-dose rate environmental radiation exposure', International Journal of Radiation Biology, vol. 90, no. 10, pp. 859-866. https://doi.org/10.3109/09553002.2014.916830
Yen, Pimei Nancy ; Lin, I. Feng ; Chang, Wushou Peter ; Wang, Jung Der ; Chang, Tien Chun ; Kuo, Kuan Liang ; Hwang, Jing Shiang ; Liu, I. Chao ; Chen, Yi Ting ; Yang, Chen Chang. / Risk factors of depression after prolonged low-dose rate environmental radiation exposure. In: International Journal of Radiation Biology. 2014 ; Vol. 90, No. 10. pp. 859-866.
@article{a35f1b75b020457ea188f8cd32fc80a0,
title = "Risk factors of depression after prolonged low-dose rate environmental radiation exposure",
abstract = "Purpose: More than 10,000 Taiwanese people were exposed to excessive protracted low-dose rate radiation from contaminated reinforcement bars, which were installed in buildings before 1992. This study was conducted to assess the prevalence of depression amongst the exposed and identify related determinants now that more than two decades have passed since this population was informed of their exposure to radiation. Materials and methods: We used the Beck depression inventory (BDI)-1A questionnaire to survey 2143 eligible people during their annual physical examinations between March 2009 and December 2009. In total, 1621 people participated in the survey. We employed multivariate logistic regression models with generalized estimating equations method to identify the determinants of depression. Results: The prevalence of depression (BDI-IA score ≥ 12) was 18.7{\%}. Those who exhibited higher cumulative exposure [adjusted odds ratio (OR): 1.46, 95{\%} confidence interval (CI): 1.02-2.07] and a previous history of depression (adjusted OR: 2.49, 95{\%} CI: 1.36-4.58) were significantly associated with the risk of depression, whereas education level was inversely related to depression (adjusted OR: 0.71, 95{\%} CI: 0.50-0.99). Conclusion: Long-term, low-dose rate radiation exposure early in life might cause subsequent psychological stress and an increased risk of depression decades later.",
keywords = "Epidemiology, health surveillance, ionizing radiation, low-dose effects, mental health, stress",
author = "Yen, {Pimei Nancy} and Lin, {I. Feng} and Chang, {Wushou Peter} and Wang, {Jung Der} and Chang, {Tien Chun} and Kuo, {Kuan Liang} and Hwang, {Jing Shiang} and Liu, {I. Chao} and Chen, {Yi Ting} and Yang, {Chen Chang}",
year = "2014",
month = "10",
day = "1",
doi = "10.3109/09553002.2014.916830",
language = "English",
volume = "90",
pages = "859--866",
journal = "International Journal of Radiation Biology",
issn = "0955-3002",
publisher = "Informa Healthcare",
number = "10",

}

TY - JOUR

T1 - Risk factors of depression after prolonged low-dose rate environmental radiation exposure

AU - Yen, Pimei Nancy

AU - Lin, I. Feng

AU - Chang, Wushou Peter

AU - Wang, Jung Der

AU - Chang, Tien Chun

AU - Kuo, Kuan Liang

AU - Hwang, Jing Shiang

AU - Liu, I. Chao

AU - Chen, Yi Ting

AU - Yang, Chen Chang

PY - 2014/10/1

Y1 - 2014/10/1

N2 - Purpose: More than 10,000 Taiwanese people were exposed to excessive protracted low-dose rate radiation from contaminated reinforcement bars, which were installed in buildings before 1992. This study was conducted to assess the prevalence of depression amongst the exposed and identify related determinants now that more than two decades have passed since this population was informed of their exposure to radiation. Materials and methods: We used the Beck depression inventory (BDI)-1A questionnaire to survey 2143 eligible people during their annual physical examinations between March 2009 and December 2009. In total, 1621 people participated in the survey. We employed multivariate logistic regression models with generalized estimating equations method to identify the determinants of depression. Results: The prevalence of depression (BDI-IA score ≥ 12) was 18.7%. Those who exhibited higher cumulative exposure [adjusted odds ratio (OR): 1.46, 95% confidence interval (CI): 1.02-2.07] and a previous history of depression (adjusted OR: 2.49, 95% CI: 1.36-4.58) were significantly associated with the risk of depression, whereas education level was inversely related to depression (adjusted OR: 0.71, 95% CI: 0.50-0.99). Conclusion: Long-term, low-dose rate radiation exposure early in life might cause subsequent psychological stress and an increased risk of depression decades later.

AB - Purpose: More than 10,000 Taiwanese people were exposed to excessive protracted low-dose rate radiation from contaminated reinforcement bars, which were installed in buildings before 1992. This study was conducted to assess the prevalence of depression amongst the exposed and identify related determinants now that more than two decades have passed since this population was informed of their exposure to radiation. Materials and methods: We used the Beck depression inventory (BDI)-1A questionnaire to survey 2143 eligible people during their annual physical examinations between March 2009 and December 2009. In total, 1621 people participated in the survey. We employed multivariate logistic regression models with generalized estimating equations method to identify the determinants of depression. Results: The prevalence of depression (BDI-IA score ≥ 12) was 18.7%. Those who exhibited higher cumulative exposure [adjusted odds ratio (OR): 1.46, 95% confidence interval (CI): 1.02-2.07] and a previous history of depression (adjusted OR: 2.49, 95% CI: 1.36-4.58) were significantly associated with the risk of depression, whereas education level was inversely related to depression (adjusted OR: 0.71, 95% CI: 0.50-0.99). Conclusion: Long-term, low-dose rate radiation exposure early in life might cause subsequent psychological stress and an increased risk of depression decades later.

KW - Epidemiology

KW - health surveillance

KW - ionizing radiation

KW - low-dose effects

KW - mental health

KW - stress

UR - http://www.scopus.com/inward/record.url?scp=84921820049&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84921820049&partnerID=8YFLogxK

U2 - 10.3109/09553002.2014.916830

DO - 10.3109/09553002.2014.916830

M3 - Article

C2 - 24766615

AN - SCOPUS:84921820049

VL - 90

SP - 859

EP - 866

JO - International Journal of Radiation Biology

JF - International Journal of Radiation Biology

SN - 0955-3002

IS - 10

ER -