Risk factors for recurrent hypoglycemia in hospitalized diabetic patients admitted for severe hypoglycemia

Yen Yue Lin, Chin Wang Hsu, Wayne Huey Herng Sheu, Shi Jye Chu, Chin Pyng Wu, Shih Hung Tsai

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Purpose: Severe hypoglycemia can result in neural damage, impaired cognitive function, coma, seizures, or death. The decision to admit diabetic patients after initial treatment in the emergency department remains unclear. Our purpose is to identify risk factors for developing recurrent hypoglycemia in diabetic patients admitted for severe hypoglycemia. Materials and Methods: We reviewed the records of 233 subjects (92 males, 141 females; mean age, 74.1 ± 9.8 years) with type 2 diabetes treated at a tertiary care teaching hospital and hospitalized for severe hypoglycemia. Results: Seventy-four (31.8%) patients were categorized with recurrent hypoglycemia and 159 (68.2%) with non-recurrent. Multivariate logistic regression analysis revealed that patients with loss of a recent meal, coronary artery disease, infection, and poor renal function (lower estimated glomerular filtration rate) were at risk for recurrent hypoglycemia. The use of calcium-channel blockers appeared to be a protective factor for the development of recurrent hypoglycemia. Conclusion: There may be a subset of patients with severe hypoglycemia and certain risk factors for recurrent hypoglycemia that should be admitted.

Original languageEnglish
Pages (from-to)367-374
Number of pages8
JournalYonsei Medical Journal
Volume51
Issue number3
DOIs
Publication statusPublished - May 2010
Externally publishedYes

Fingerprint

Hypoglycemia
Calcium Channel Blockers
Tertiary Healthcare
Coma
Glomerular Filtration Rate
Teaching Hospitals
Type 2 Diabetes Mellitus
Cognition
Meals
Hospital Emergency Service
Coronary Artery Disease
Seizures
Logistic Models
Regression Analysis
Kidney
Infection

Keywords

  • Calcium channel blockers
  • Chronic kidney disease
  • Coronary artery disease
  • Diabetic complications
  • Hypoglycemia
  • Mellitus
  • Type 2 diabetes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Risk factors for recurrent hypoglycemia in hospitalized diabetic patients admitted for severe hypoglycemia. / Lin, Yen Yue; Hsu, Chin Wang; Sheu, Wayne Huey Herng; Chu, Shi Jye; Wu, Chin Pyng; Tsai, Shih Hung.

In: Yonsei Medical Journal, Vol. 51, No. 3, 05.2010, p. 367-374.

Research output: Contribution to journalArticle

Lin, Yen Yue ; Hsu, Chin Wang ; Sheu, Wayne Huey Herng ; Chu, Shi Jye ; Wu, Chin Pyng ; Tsai, Shih Hung. / Risk factors for recurrent hypoglycemia in hospitalized diabetic patients admitted for severe hypoglycemia. In: Yonsei Medical Journal. 2010 ; Vol. 51, No. 3. pp. 367-374.
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