Risk and outcomes for traumatic brain injury in patients with mental disorders

Chien Chang Liao, Wen Ta Chiu, Chun Chieh Yeh, Huai Chia Chang, Ta Liang Chen

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objective: To investigate the risk of traumatic brain injury (TBI) and post-injury mortality in patients with mental disorders. Background: Patients with mental disorders are at higher risk of injuries. However, the association between mental disorders and TBI is still not understood. We conducted case-control studies to investigate whether people with pre-existing mental disorders are at higher risk of TBI and post-injury mortality. Methods: Using reimbursement claims, we analysed 16 635 patients with TBI and 66 540 controls with adjustment of covariates to study the association of mental disorders and TBI. A nested case-control study was also conducted to analyse contributory factors for post-injury mortality. Results: People with mental disorders were at increased risk of TBI (odds ratio (OR) 1.94, 95% confidence interval (CI) 1.86 to 2.02). Men, older age, living in highly urbanised areas and patients on low income had a higher risk of TBI and post-injury mortality. Psychiatric medication intensity and frequency of psychiatric visits was significantly correlated with TBI in a severity dependent relationship (p for trend

Original languageEnglish
Pages (from-to)1186-1192
Number of pages7
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume83
Issue number12
DOIs
Publication statusPublished - Dec 2012

Fingerprint

Mental Disorders
Wounds and Injuries
Mortality
Psychiatry
Case-Control Studies
Social Adjustment
Preexisting Condition Coverage
Traumatic Brain Injury
Statistical Factor Analysis
Odds Ratio
Confidence Intervals

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Surgery
  • Arts and Humanities (miscellaneous)

Cite this

Risk and outcomes for traumatic brain injury in patients with mental disorders. / Liao, Chien Chang; Chiu, Wen Ta; Yeh, Chun Chieh; Chang, Huai Chia; Chen, Ta Liang.

In: Journal of Neurology, Neurosurgery and Psychiatry, Vol. 83, No. 12, 12.2012, p. 1186-1192.

Research output: Contribution to journalArticle

@article{a6bc2321cc864b61a0013bb9f9957a0c,
title = "Risk and outcomes for traumatic brain injury in patients with mental disorders",
abstract = "Objective: To investigate the risk of traumatic brain injury (TBI) and post-injury mortality in patients with mental disorders. Background: Patients with mental disorders are at higher risk of injuries. However, the association between mental disorders and TBI is still not understood. We conducted case-control studies to investigate whether people with pre-existing mental disorders are at higher risk of TBI and post-injury mortality. Methods: Using reimbursement claims, we analysed 16 635 patients with TBI and 66 540 controls with adjustment of covariates to study the association of mental disorders and TBI. A nested case-control study was also conducted to analyse contributory factors for post-injury mortality. Results: People with mental disorders were at increased risk of TBI (odds ratio (OR) 1.94, 95{\%} confidence interval (CI) 1.86 to 2.02). Men, older age, living in highly urbanised areas and patients on low income had a higher risk of TBI and post-injury mortality. Psychiatric medication intensity and frequency of psychiatric visits was significantly correlated with TBI in a severity dependent relationship (p for trend",
author = "Liao, {Chien Chang} and Chiu, {Wen Ta} and Yeh, {Chun Chieh} and Chang, {Huai Chia} and Chen, {Ta Liang}",
year = "2012",
month = "12",
doi = "10.1136/jnnp-2012-302337",
language = "English",
volume = "83",
pages = "1186--1192",
journal = "Journal of Neurology, Neurosurgery and Psychiatry",
issn = "0022-3050",
publisher = "BMJ Publishing Group",
number = "12",

}

TY - JOUR

T1 - Risk and outcomes for traumatic brain injury in patients with mental disorders

AU - Liao, Chien Chang

AU - Chiu, Wen Ta

AU - Yeh, Chun Chieh

AU - Chang, Huai Chia

AU - Chen, Ta Liang

PY - 2012/12

Y1 - 2012/12

N2 - Objective: To investigate the risk of traumatic brain injury (TBI) and post-injury mortality in patients with mental disorders. Background: Patients with mental disorders are at higher risk of injuries. However, the association between mental disorders and TBI is still not understood. We conducted case-control studies to investigate whether people with pre-existing mental disorders are at higher risk of TBI and post-injury mortality. Methods: Using reimbursement claims, we analysed 16 635 patients with TBI and 66 540 controls with adjustment of covariates to study the association of mental disorders and TBI. A nested case-control study was also conducted to analyse contributory factors for post-injury mortality. Results: People with mental disorders were at increased risk of TBI (odds ratio (OR) 1.94, 95% confidence interval (CI) 1.86 to 2.02). Men, older age, living in highly urbanised areas and patients on low income had a higher risk of TBI and post-injury mortality. Psychiatric medication intensity and frequency of psychiatric visits was significantly correlated with TBI in a severity dependent relationship (p for trend

AB - Objective: To investigate the risk of traumatic brain injury (TBI) and post-injury mortality in patients with mental disorders. Background: Patients with mental disorders are at higher risk of injuries. However, the association between mental disorders and TBI is still not understood. We conducted case-control studies to investigate whether people with pre-existing mental disorders are at higher risk of TBI and post-injury mortality. Methods: Using reimbursement claims, we analysed 16 635 patients with TBI and 66 540 controls with adjustment of covariates to study the association of mental disorders and TBI. A nested case-control study was also conducted to analyse contributory factors for post-injury mortality. Results: People with mental disorders were at increased risk of TBI (odds ratio (OR) 1.94, 95% confidence interval (CI) 1.86 to 2.02). Men, older age, living in highly urbanised areas and patients on low income had a higher risk of TBI and post-injury mortality. Psychiatric medication intensity and frequency of psychiatric visits was significantly correlated with TBI in a severity dependent relationship (p for trend

UR - http://www.scopus.com/inward/record.url?scp=84869239737&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84869239737&partnerID=8YFLogxK

U2 - 10.1136/jnnp-2012-302337

DO - 10.1136/jnnp-2012-302337

M3 - Article

C2 - 22773855

AN - SCOPUS:84869239737

VL - 83

SP - 1186

EP - 1192

JO - Journal of Neurology, Neurosurgery and Psychiatry

JF - Journal of Neurology, Neurosurgery and Psychiatry

SN - 0022-3050

IS - 12

ER -