Revisit of 1997 TNM staging system - Survival analysis of 1112 lung cancer patients in Taiwan

Reury Perng Perng, Chih Yi Chen, Gee Chen Chang, Te Chun Hsia, Nan Yung Hsu, Ying Huang Tsai, Chun Ming Tsai, Chih Hsin Yang, Yuh Min Chen, Chong Jen Yu, Jen Jyh Lee, Han Shui Hsu, Chih Teng Yu, Eing Long Kao, Chao Hua Chiu

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Abstract

Background: There is neither a nation-wide nor a large-scale, multi-institutional lung cancer database available for stage-by-stage survival analysis in Taiwan at present. Methods: Using the data element provided by the International Association for the Study of Lung Cancer, the Taiwan Lung Cancer Society initiated a project to include native lung cancer patients into a global database. A total of 1112 Taiwan lung cancer patients treated in 7 medical centers were enrolled. Results: In small cell lung cancer, patients with ipsilateral pleural effusion had a survival between those with locoregional disease alone and those with distant metastasis; however, the difference was not statistically significant (P = 0.204). In non-small cell lung cancer, tumor size had significant survival influence for patients as a whole (P <0.001) but it did not support the further division of stage IA according to tumor size (P = 0.122). The survival was compatible in stage IIIB and IV patients and therefore, the survival impact of pleural effusion cannot be determined. In patients with pIIIA-N2 disease, those who had station 8 nodal metastasis had inferior survival (P = 0.020) and station 5 superior survival (P = 0.010). In patients with distant metastasis, bone, liver, or distant lymph node metastasis predicted an inferior survival (all P values <0.05). Conclusions: The present study provides for comparison in this area a stage-by-stage reference for the survival of lung cancer patients. Some factors other than current TNM descriptors need to be further investigated in constructing the next version of the staging system.

Original languageEnglish
Pages (from-to)9-15
Number of pages7
JournalJapanese Journal of Clinical Oncology
Volume37
Issue number1
DOIs
Publication statusPublished - Jan 2007
Externally publishedYes

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Neoplasm Staging
Survival Analysis
Taiwan
Lung Neoplasms
Survival
Neoplasm Metastasis
Pleural Effusion
Databases
Small Cell Lung Carcinoma
Population Groups
Non-Small Cell Lung Carcinoma
Neoplasms
Lymph Nodes
Bone and Bones
Liver

Keywords

  • Lung cancer
  • Survival analysis
  • Taiwan
  • TNM staging system

ASJC Scopus subject areas

  • Oncology

Cite this

Perng, R. P., Chen, C. Y., Chang, G. C., Hsia, T. C., Hsu, N. Y., Tsai, Y. H., ... Chiu, C. H. (2007). Revisit of 1997 TNM staging system - Survival analysis of 1112 lung cancer patients in Taiwan. Japanese Journal of Clinical Oncology, 37(1), 9-15. https://doi.org/10.1093/jjco/hyl119

Revisit of 1997 TNM staging system - Survival analysis of 1112 lung cancer patients in Taiwan. / Perng, Reury Perng; Chen, Chih Yi; Chang, Gee Chen; Hsia, Te Chun; Hsu, Nan Yung; Tsai, Ying Huang; Tsai, Chun Ming; Yang, Chih Hsin; Chen, Yuh Min; Yu, Chong Jen; Lee, Jen Jyh; Hsu, Han Shui; Yu, Chih Teng; Kao, Eing Long; Chiu, Chao Hua.

In: Japanese Journal of Clinical Oncology, Vol. 37, No. 1, 01.2007, p. 9-15.

Research output: Contribution to journalArticle

Perng, RP, Chen, CY, Chang, GC, Hsia, TC, Hsu, NY, Tsai, YH, Tsai, CM, Yang, CH, Chen, YM, Yu, CJ, Lee, JJ, Hsu, HS, Yu, CT, Kao, EL & Chiu, CH 2007, 'Revisit of 1997 TNM staging system - Survival analysis of 1112 lung cancer patients in Taiwan', Japanese Journal of Clinical Oncology, vol. 37, no. 1, pp. 9-15. https://doi.org/10.1093/jjco/hyl119
Perng, Reury Perng ; Chen, Chih Yi ; Chang, Gee Chen ; Hsia, Te Chun ; Hsu, Nan Yung ; Tsai, Ying Huang ; Tsai, Chun Ming ; Yang, Chih Hsin ; Chen, Yuh Min ; Yu, Chong Jen ; Lee, Jen Jyh ; Hsu, Han Shui ; Yu, Chih Teng ; Kao, Eing Long ; Chiu, Chao Hua. / Revisit of 1997 TNM staging system - Survival analysis of 1112 lung cancer patients in Taiwan. In: Japanese Journal of Clinical Oncology. 2007 ; Vol. 37, No. 1. pp. 9-15.
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AU - Hsia, Te Chun

AU - Hsu, Nan Yung

AU - Tsai, Ying Huang

AU - Tsai, Chun Ming

AU - Yang, Chih Hsin

AU - Chen, Yuh Min

AU - Yu, Chong Jen

AU - Lee, Jen Jyh

AU - Hsu, Han Shui

AU - Yu, Chih Teng

AU - Kao, Eing Long

AU - Chiu, Chao Hua

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