Retroperitoneal Undifferentiated Sarcoma in a Hemodialysis Patient

Research output: Contribution to journalArticle

Abstract

Retroperitoneal undifferentiated sarcoma is a soft tissue sarcoma that is highly positive for vimentin but has no reactions to various cell-specific markers in immunohistochemical study. This tumor has never been reported in a hemodialysis patient with chronically immunosuppressed uremic state. We report a case of retroperitoneal undifferentiated sarcoma in a 50-year-old uremic man who presented with intermittent left flank dull pain and painless hematuria. MRI revealed a huge left perirenal mass, and complete resection was achieved. The pathological examination of the tumor cells revealed poorly-differentiated spindle or oval-shaped sarcoma cells, and the immunohistochemical study excluded the diagnosis of rhabdomyosarcoma, leimyosarcoma, liposarcoma, angiomyolipoma, sarcomatoid renal cell carcinoma, and sarcomatoid transitional cell carcinoma. This indicated that the sarcoma did not show any differentiation. The patient had an uneventful postoperative course and is currently well 3 years after operation. We review the clinical picture of this tumor in a hemodialysis patient, elucidate the ”undifferentiated” histopathological characteristics by immunohistochemical study and point out the possible connection between sarcoma formation and immunosuppressive status from uremia.
Original languageEnglish
Pages (from-to)246-250
Number of pages5
JournalFormosan Journal of Surgery
Volume38
Issue number5
DOIs
Publication statusPublished - Oct 1 2005

Fingerprint

Sarcoma
Renal Dialysis
Flank Pain
Angiomyolipoma
Liposarcoma
Neoplasms
Rhabdomyosarcoma
Transitional Cell Carcinoma
Uremia
Vimentin
Hematuria
Immunosuppressive Agents
Renal Cell Carcinoma

Cite this

Retroperitoneal Undifferentiated Sarcoma in a Hemodialysis Patient. / Chen, Kuan-Chou; Lin, Yun-Ho.

In: Formosan Journal of Surgery, Vol. 38, No. 5, 01.10.2005, p. 246-250.

Research output: Contribution to journalArticle

@article{33ea0535cfd1412ca96bb31863f378ee,
title = "Retroperitoneal Undifferentiated Sarcoma in a Hemodialysis Patient",
abstract = "Retroperitoneal undifferentiated sarcoma is a soft tissue sarcoma that is highly positive for vimentin but has no reactions to various cell-specific markers in immunohistochemical study. This tumor has never been reported in a hemodialysis patient with chronically immunosuppressed uremic state. We report a case of retroperitoneal undifferentiated sarcoma in a 50-year-old uremic man who presented with intermittent left flank dull pain and painless hematuria. MRI revealed a huge left perirenal mass, and complete resection was achieved. The pathological examination of the tumor cells revealed poorly-differentiated spindle or oval-shaped sarcoma cells, and the immunohistochemical study excluded the diagnosis of rhabdomyosarcoma, leimyosarcoma, liposarcoma, angiomyolipoma, sarcomatoid renal cell carcinoma, and sarcomatoid transitional cell carcinoma. This indicated that the sarcoma did not show any differentiation. The patient had an uneventful postoperative course and is currently well 3 years after operation. We review the clinical picture of this tumor in a hemodialysis patient, elucidate the ”undifferentiated” histopathological characteristics by immunohistochemical study and point out the possible connection between sarcoma formation and immunosuppressive status from uremia.",
keywords = "retroperitoneal sarcoma, undifferentiated sarcoma, hemodialysis, immunohistochemical study",
author = "Kuan-Chou Chen and Yun-Ho Lin",
year = "2005",
month = "10",
day = "1",
doi = "10.29833/FJS.200510.0006",
language = "English",
volume = "38",
pages = "246--250",
journal = "Formosan Journal of Surgery",
issn = "1011-6788",
publisher = "臺灣外科醫學會",
number = "5",

}

TY - JOUR

T1 - Retroperitoneal Undifferentiated Sarcoma in a Hemodialysis Patient

AU - Chen, Kuan-Chou

AU - Lin, Yun-Ho

PY - 2005/10/1

Y1 - 2005/10/1

N2 - Retroperitoneal undifferentiated sarcoma is a soft tissue sarcoma that is highly positive for vimentin but has no reactions to various cell-specific markers in immunohistochemical study. This tumor has never been reported in a hemodialysis patient with chronically immunosuppressed uremic state. We report a case of retroperitoneal undifferentiated sarcoma in a 50-year-old uremic man who presented with intermittent left flank dull pain and painless hematuria. MRI revealed a huge left perirenal mass, and complete resection was achieved. The pathological examination of the tumor cells revealed poorly-differentiated spindle or oval-shaped sarcoma cells, and the immunohistochemical study excluded the diagnosis of rhabdomyosarcoma, leimyosarcoma, liposarcoma, angiomyolipoma, sarcomatoid renal cell carcinoma, and sarcomatoid transitional cell carcinoma. This indicated that the sarcoma did not show any differentiation. The patient had an uneventful postoperative course and is currently well 3 years after operation. We review the clinical picture of this tumor in a hemodialysis patient, elucidate the ”undifferentiated” histopathological characteristics by immunohistochemical study and point out the possible connection between sarcoma formation and immunosuppressive status from uremia.

AB - Retroperitoneal undifferentiated sarcoma is a soft tissue sarcoma that is highly positive for vimentin but has no reactions to various cell-specific markers in immunohistochemical study. This tumor has never been reported in a hemodialysis patient with chronically immunosuppressed uremic state. We report a case of retroperitoneal undifferentiated sarcoma in a 50-year-old uremic man who presented with intermittent left flank dull pain and painless hematuria. MRI revealed a huge left perirenal mass, and complete resection was achieved. The pathological examination of the tumor cells revealed poorly-differentiated spindle or oval-shaped sarcoma cells, and the immunohistochemical study excluded the diagnosis of rhabdomyosarcoma, leimyosarcoma, liposarcoma, angiomyolipoma, sarcomatoid renal cell carcinoma, and sarcomatoid transitional cell carcinoma. This indicated that the sarcoma did not show any differentiation. The patient had an uneventful postoperative course and is currently well 3 years after operation. We review the clinical picture of this tumor in a hemodialysis patient, elucidate the ”undifferentiated” histopathological characteristics by immunohistochemical study and point out the possible connection between sarcoma formation and immunosuppressive status from uremia.

KW - retroperitoneal sarcoma

KW - undifferentiated sarcoma

KW - hemodialysis

KW - immunohistochemical study

U2 - 10.29833/FJS.200510.0006

DO - 10.29833/FJS.200510.0006

M3 - Article

VL - 38

SP - 246

EP - 250

JO - Formosan Journal of Surgery

JF - Formosan Journal of Surgery

SN - 1011-6788

IS - 5

ER -