Resting-state functional magnetic resonance imaging: Review of neurosurgical applications

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Recent research in brain imaging has highlighted the role of different neural networks in the resting state (ie, no task) in which the brain displays spontaneous low-frequency neuronal oscillations. These can be indirectly measured with resting-state functional magnetic resonance imaging, and functional connectivity can be inferred as the spatiotemporal correlations of this signal. This technique has proliferated in recent years and has allowed the noninvasive investigation of large-scale, distributed functional networks. In this review, we give a brief overview of resting-state networks and examine the use of resting-state functional magnetic resonance imaging in neurosurgical contexts, specifically with respect to neurooncology, epilepsy surgery, and deep brain stimulation. We discuss the advantages and disadvantages compared with task-based functional magnetic resonance imaging, the limitations of resting-state functional magnetic resonance imaging, and the emerging directions of this relatively new technology. ABBREVIATIONS:: BOLD, blood oxygen level-dependentDBS, deep brain stimulationICA, independent component analysisMTLE, medial temporal lobe epilepsyROI, region of interestrs-fMRI, resting-state functional magnetic resonance imagingRSN, resting-state network

Original languageEnglish
Pages (from-to)453-464
Number of pages12
JournalNeurosurgery
Volume74
Issue number5
DOIs
Publication statusPublished - 2014
Externally publishedYes

Keywords

  • Fmri
  • Neurosurgery

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Medicine(all)

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