Resting-state functional magnetic resonance imaging: Review of neurosurgical applications

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Recent research in brain imaging has highlighted the role of different neural networks in the resting state (ie, no task) in which the brain displays spontaneous low-frequency neuronal oscillations. These can be indirectly measured with resting-state functional magnetic resonance imaging, and functional connectivity can be inferred as the spatiotemporal correlations of this signal. This technique has proliferated in recent years and has allowed the noninvasive investigation of large-scale, distributed functional networks. In this review, we give a brief overview of resting-state networks and examine the use of resting-state functional magnetic resonance imaging in neurosurgical contexts, specifically with respect to neurooncology, epilepsy surgery, and deep brain stimulation. We discuss the advantages and disadvantages compared with task-based functional magnetic resonance imaging, the limitations of resting-state functional magnetic resonance imaging, and the emerging directions of this relatively new technology. ABBREVIATIONS:: BOLD, blood oxygen level-dependentDBS, deep brain stimulationICA, independent component analysisMTLE, medial temporal lobe epilepsyROI, region of interestrs-fMRI, resting-state functional magnetic resonance imagingRSN, resting-state network

Original languageEnglish
Pages (from-to)453-464
Number of pages12
JournalNeurosurgery
Volume74
Issue number5
DOIs
Publication statusPublished - 2014
Externally publishedYes

Fingerprint

Magnetic Resonance Imaging
Deep Brain Stimulation
Brain
Temporal Lobe
Neuroimaging
Epilepsy
Magnetic Resonance Spectroscopy
Oxygen
Technology
Research

Keywords

  • Fmri
  • Neurosurgery

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Medicine(all)

Cite this

Resting-state functional magnetic resonance imaging : Review of neurosurgical applications. / Lang, Stefan; Duncan, Niall; Northoff, Georg.

In: Neurosurgery, Vol. 74, No. 5, 2014, p. 453-464.

Research output: Contribution to journalArticle

@article{cb54723920dd4359997e52127a0cf105,
title = "Resting-state functional magnetic resonance imaging: Review of neurosurgical applications",
abstract = "Recent research in brain imaging has highlighted the role of different neural networks in the resting state (ie, no task) in which the brain displays spontaneous low-frequency neuronal oscillations. These can be indirectly measured with resting-state functional magnetic resonance imaging, and functional connectivity can be inferred as the spatiotemporal correlations of this signal. This technique has proliferated in recent years and has allowed the noninvasive investigation of large-scale, distributed functional networks. In this review, we give a brief overview of resting-state networks and examine the use of resting-state functional magnetic resonance imaging in neurosurgical contexts, specifically with respect to neurooncology, epilepsy surgery, and deep brain stimulation. We discuss the advantages and disadvantages compared with task-based functional magnetic resonance imaging, the limitations of resting-state functional magnetic resonance imaging, and the emerging directions of this relatively new technology. ABBREVIATIONS:: BOLD, blood oxygen level-dependentDBS, deep brain stimulationICA, independent component analysisMTLE, medial temporal lobe epilepsyROI, region of interestrs-fMRI, resting-state functional magnetic resonance imagingRSN, resting-state network",
keywords = "Fmri, Neurosurgery",
author = "Stefan Lang and Niall Duncan and Georg Northoff",
year = "2014",
doi = "10.1227/NEU.0000000000000307",
language = "English",
volume = "74",
pages = "453--464",
journal = "Neurosurgery",
issn = "0148-396X",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Resting-state functional magnetic resonance imaging

T2 - Review of neurosurgical applications

AU - Lang, Stefan

AU - Duncan, Niall

AU - Northoff, Georg

PY - 2014

Y1 - 2014

N2 - Recent research in brain imaging has highlighted the role of different neural networks in the resting state (ie, no task) in which the brain displays spontaneous low-frequency neuronal oscillations. These can be indirectly measured with resting-state functional magnetic resonance imaging, and functional connectivity can be inferred as the spatiotemporal correlations of this signal. This technique has proliferated in recent years and has allowed the noninvasive investigation of large-scale, distributed functional networks. In this review, we give a brief overview of resting-state networks and examine the use of resting-state functional magnetic resonance imaging in neurosurgical contexts, specifically with respect to neurooncology, epilepsy surgery, and deep brain stimulation. We discuss the advantages and disadvantages compared with task-based functional magnetic resonance imaging, the limitations of resting-state functional magnetic resonance imaging, and the emerging directions of this relatively new technology. ABBREVIATIONS:: BOLD, blood oxygen level-dependentDBS, deep brain stimulationICA, independent component analysisMTLE, medial temporal lobe epilepsyROI, region of interestrs-fMRI, resting-state functional magnetic resonance imagingRSN, resting-state network

AB - Recent research in brain imaging has highlighted the role of different neural networks in the resting state (ie, no task) in which the brain displays spontaneous low-frequency neuronal oscillations. These can be indirectly measured with resting-state functional magnetic resonance imaging, and functional connectivity can be inferred as the spatiotemporal correlations of this signal. This technique has proliferated in recent years and has allowed the noninvasive investigation of large-scale, distributed functional networks. In this review, we give a brief overview of resting-state networks and examine the use of resting-state functional magnetic resonance imaging in neurosurgical contexts, specifically with respect to neurooncology, epilepsy surgery, and deep brain stimulation. We discuss the advantages and disadvantages compared with task-based functional magnetic resonance imaging, the limitations of resting-state functional magnetic resonance imaging, and the emerging directions of this relatively new technology. ABBREVIATIONS:: BOLD, blood oxygen level-dependentDBS, deep brain stimulationICA, independent component analysisMTLE, medial temporal lobe epilepsyROI, region of interestrs-fMRI, resting-state functional magnetic resonance imagingRSN, resting-state network

KW - Fmri

KW - Neurosurgery

UR - http://www.scopus.com/inward/record.url?scp=84899642768&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84899642768&partnerID=8YFLogxK

U2 - 10.1227/NEU.0000000000000307

DO - 10.1227/NEU.0000000000000307

M3 - Article

C2 - 24492661

AN - SCOPUS:84899642768

VL - 74

SP - 453

EP - 464

JO - Neurosurgery

JF - Neurosurgery

SN - 0148-396X

IS - 5

ER -