Research of phase transformation induced biodegradable properties on hydroxyapatite and tricalcium phosphate based bioceramic

Kuo Tien Chu, Shih Fu Ou, Shyuan Yow Chen, Shi Yung Chiou, Hsin Hua Chou, Keng Liang Ou

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22 Citations (Scopus)


Biodegradable calcium phosphate composites consisting of tricalcium phosphate (α-TCP) and hydroxyapatite (HA) were prepared using a two-step sintering method. The ratio of α-TCP/HA was controlled by modulating the sintering temperature. The initial calcination process at 800 °C causes HA dehydroxylation and induces the early transformation of HA into α-TCP in subsequent sintering processes. At the optimum sintering temperature of 1300 °C, the material is comprised of a moderate ratio of α-TCP to HA (3:7) and possesses a hardness of 5.0 GPa. The high temperature phase transformation from HA to α-TCP accompanied by bonded water loss, which results in the formation of nano-pores within the α-TCP matrix, hardly deteriorated the mechanical strength of the composite. This pore-containing structure also provided a convincing evidence for the origin of the high degradability of α-TCP in a biological environment.

Original languageEnglish
Pages (from-to)1455-1462
Number of pages8
JournalCeramics International
Issue number2
Publication statusPublished - Mar 2013



  • α-tricalcium phosphate
  • A. Sintering
  • Dehydroxylation
  • Hydroxyapatite

ASJC Scopus subject areas

  • Ceramics and Composites
  • Process Chemistry and Technology
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry

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