Research of electrosurgical ablation with antiadhesive functionalization on thermal and histopathological effects of brain tissues in vivo

Wen Tien Hsiao, Chun Ming Kung, Jan Show Chu, Keng Liang Ou, Pei Wen Peng

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Thermal injury and tissue sticking are two major concerns in the electrosurgery. In the present study, the effect of lateral thermal injury caused by different electrosurgical electrodes on wound healing was investigated. An electrosurgical unit equipped with untreated (SS) and titanium oxide layer-coated (TiO2-coated) stainless steel needle-type electrodes was used to create lesions on the rat brain tissue. TiO2 layers were produced by radiofrequency plasma and magnetron sputtering in the form of amorphous (TO-SS-1), anatase (TO-SS-2), and rutile (TO-SS-3) phase. Animals were sacrificed for evaluations at 0, 2, 7, and 28 days postoperatively. TO-SS-3 electrodes generated lower levels of sticking tissue, and the thermographs showed that the recorded highest temperature in brain tissue from the TO-SS-3 electrode was significantly lower than in the SS electrode. The total injury area of brain tissue caused by TO-SS-1 and TO-SS-3 electrodes was significantly lower than that caused by SS electrodes at each time point. The results of the present study reveal that the plating of electrodes with a TiO2 film with rutile phases is an efficient method for improving the performance of electrosurgical units and should benefit wound healing.

Original languageEnglish
Article number182657
JournalBioMed Research International
Volume2014
DOIs
Publication statusPublished - 2014

Fingerprint

Ablation
Brain
Electrodes
Hot Temperature
Tissue
Research
Wound Healing
Electrosurgery
Stainless Steel
Wounds and Injuries
Plating
Needles
Magnetron sputtering
Brain Injuries
Rats
Animals
Plasmas
Temperature
titanium dioxide

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Medicine(all)

Cite this

Research of electrosurgical ablation with antiadhesive functionalization on thermal and histopathological effects of brain tissues in vivo. / Hsiao, Wen Tien; Kung, Chun Ming; Chu, Jan Show; Ou, Keng Liang; Peng, Pei Wen.

In: BioMed Research International, Vol. 2014, 182657, 2014.

Research output: Contribution to journalArticle

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