Abstract

© 2018 Po-Chi Chan et al. Rapid eye movement sleep behavior disorder (RBD) is a parasomnia, with abnormal dream-enacting behavior during the rapid eye movement (REM) sleep. RBD is either idiopathic or secondary to other neurologic disorders and medications. Dementia with Lewy bodies (DLB) is the third most common cause of dementia, and the typical clinical presentation is rapidly progressive cognitive impairment. RBD is one of the core features of DLB and may occur either in advance or simultaneously with the onset of DLB. The association between RBD with DLB is widely studied. Evidences suggest that both DLB and RBD are possibly caused by the shared underlying synucleinopathy. This review article discusses history, clinical manifestations, possible pathophysiologies, and treatment of DLB and RBD and provides the latest updates.
Original languageEnglish
JournalBehavioural Neurology
Volume2018
DOIs
Publication statusPublished - Jan 1 2018

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REM Sleep Behavior Disorder
Lewy Body Disease
Parasomnias
REM Sleep
Nervous System Diseases
Dementia
Sleep
History

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REM sleep behavior disorder (RBD) in dementia with lewy bodies (DLB). / Chan, Po Chi; Lee, Hsun Hua; Hong, Chien Tai; Hu, Chaur Jong; Wu, Dean.

In: Behavioural Neurology, Vol. 2018, 01.01.2018.

Research output: Contribution to journalReview article

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