Relationship between electroencephalogram slow-wave magnitude and heart rate variability during sleep in rats

Cheryl C H Yang, Fu Zen Shaw, Ching J. Lai, Chi Wan Lai, Terry B J Kuo

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

To explore whether depth of sleep is related to changes in autonomic control in rats, continuous power-spectral analysis of electroencephalogram (EEG) and heart rate variability (HRV) was performed in unanesthetized rats during normal daytime sleep. Quiet sleep (QS) was associated with an increase in high-frequency power of HRV (0.6-2.4 Hz, HF) but a decrease in low-frequency power (0.06-0.6 Hz) to HF ratio (LF/HF) compared with awakening. During QS, LF/HF was significantly and negatively correlated with delta power of EEG (0.5-4.0 Hz), whereas mean R-R interval and HF were not. As in humans, cardiac sympathetic regulation in rats is negatively related to the depth of sleep during QS, although vagal regulation is not. Our methodology offers a parallel way of studying the interaction between cerebral cortical and autonomic functions in rats.

Original languageEnglish
Pages (from-to)21-24
Number of pages4
JournalNeuroscience Letters
Volume336
Issue number1
DOIs
Publication statusPublished - Jan 9 2003
Externally publishedYes

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Electroencephalography
Sleep
Heart Rate
Power (Psychology)

Keywords

  • Autonomic nervous system
  • Electroencephalogram
  • Heart rate variability
  • Parasympathetic activity
  • Power-spectral analysis
  • Sleep
  • Slow wave
  • Sympathetic activity

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Relationship between electroencephalogram slow-wave magnitude and heart rate variability during sleep in rats. / Yang, Cheryl C H; Shaw, Fu Zen; Lai, Ching J.; Lai, Chi Wan; Kuo, Terry B J.

In: Neuroscience Letters, Vol. 336, No. 1, 09.01.2003, p. 21-24.

Research output: Contribution to journalArticle

Yang, Cheryl C H ; Shaw, Fu Zen ; Lai, Ching J. ; Lai, Chi Wan ; Kuo, Terry B J. / Relationship between electroencephalogram slow-wave magnitude and heart rate variability during sleep in rats. In: Neuroscience Letters. 2003 ; Vol. 336, No. 1. pp. 21-24.
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