Recovery of cutaneous vasomotor activity in the spinal dog

J. C. Liu, T. T. Shyy, S. H. Tsai

Research output: Contribution to journalArticle

Abstract

Vasomotor responses of the glabrous skin of the fore and hind feet of six adult female dogs subjected to thermal stress, by cooling or warming the periphery or the spinal cord, were compared in the intact and thoracic spinal animal. In the intact dog the temperature of the forefeet at a neutral ambient temperature (22°C) was higher than the hind feet. After spinal transection the hind feet were warmer than the forefeet for several days, recovering their preoperative temperature by 6.0 ± 0.89 days. The vasomotor response to cooling (13°C) and warming (45°C) one hind limb in the intact animal induced a drop or elevation respectively in the temperature of the contralateral hind foot. This reflex response to peripheral cooling was abolished for several weeks after transection but had recovered by the 29.3 ± 2.94 day. Cooling and warming of the spinal cord below the level of transection by extradurally implanted thermodes failed to induce vasomotor responses in the hind foot pads for several weeks, recovering by the 27.1 ± 3.48 day. It is concluded that whereas thermal regulation by appropriate vasomotor response to peripheral cooling and warming is influenced by supraspinal systems, the vasomotor response recovers and functions appropriately after spinal shock has subsided. This finding contrasts with the failure of spinal animals to regulate body temperature by shivering after peripheral cooling and suggests that vasomotor regulation of body temperature is a primitive thermoregulatory response.

Original languageEnglish
Pages (from-to)654-666
Number of pages13
JournalExperimental Neurology
Volume65
Issue number3
DOIs
Publication statusPublished - 1979
Externally publishedYes

Fingerprint

Foot
Dogs
Skin
Temperature
Vasomotor System
Spinal Cord
Hot Temperature
Shivering
Body Temperature Regulation
Body Temperature
Reflex
Shock
Thorax
Extremities

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neurology

Cite this

Recovery of cutaneous vasomotor activity in the spinal dog. / Liu, J. C.; Shyy, T. T.; Tsai, S. H.

In: Experimental Neurology, Vol. 65, No. 3, 1979, p. 654-666.

Research output: Contribution to journalArticle

Liu, J. C. ; Shyy, T. T. ; Tsai, S. H. / Recovery of cutaneous vasomotor activity in the spinal dog. In: Experimental Neurology. 1979 ; Vol. 65, No. 3. pp. 654-666.
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