Reconstruction of the complete loss of upper and lower lips with a chimeric anterolateral thigh flap: A case report

Chien-Liang Lai, Kuang-Wen Ou, Wen-Kuan Chiu, Shyi-Gen Chen, Tim-Mo Chen, Hsiao-Ping Li, Shun-Cheng Chang

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


It is difficult to totally reconstruct the lips and achieve good functional and aesthetic results, such as oral sphincter function, sensation, appearance, color, and movement. There have been few reports of reconstructing complete lip defects. We present a case of completely reconstructing the lip defects of a 55-year-old patient who had verrucous carcinoma of the buccal mucosa and lips. Extensive ablation was performed by wide bilateral excision of the buccal mucosa and marginal resection of the anterior mandible and both lips. The tongue, partial tongue base mucosa, and retromolar trigone were preserved. To reconstruct and resurface the intraoral and lip defects nearly totally, we applied a free anterolateral thigh (ALT) flap in chimeric style with two independent sets of perforators and skin islands. To achieve better oral function and cosmetics, revisions of the ALT flap, full-thickness scrotal skin grafting, autologous fat grafting, and skin tattooing were done in stages. Postoperative oral sphincter function was obtained without drooling; the general appearance of the lips was also acceptable. © 2011 Wiley Periodicals, Inc.
Original languageEnglish
Pages (from-to)60-63
Number of pages4
Issue number1
Publication statusPublished - 2012
Externally publishedYes


  • adult
  • anterolateral thigh flap
  • article
  • biopsy
  • cancer staging
  • case report
  • cheek mucosa
  • chimeric flap
  • follow up
  • full thickness skin graft
  • human
  • human tissue
  • hypersalivation
  • leukoplakia
  • lip reconstruction
  • lower lip
  • lymph node dissection
  • male
  • mandible
  • priority journal
  • skin island flap
  • surgical technique
  • tongue
  • tooth extraction
  • tumor ablation
  • upper lip
  • verrucous carcinoma
  • Carcinoma, Squamous Cell
  • Cheek
  • Free Tissue Flaps
  • Head and Neck Neoplasms
  • Humans
  • Lip
  • Lip Neoplasms
  • Male
  • Middle Aged
  • Mouth Mucosa
  • Oral Surgical Procedures
  • Reconstructive Surgical Procedures


Dive into the research topics of 'Reconstruction of the complete loss of upper and lower lips with a chimeric anterolateral thigh flap: A case report'. Together they form a unique fingerprint.

Cite this