Reciprocal Translocation in Small-Cell Sarcomas

Jean Pierre de Chadarevian, Michel Vekemans, Thomas A. Seemayer, Jacqueline Whang-Peng, Timothy J. Triche, Turid Knutsen, James Miser, Mark A. Israel

Research output: Contribution to journalLetter

31 Citations (Scopus)

Abstract

To the Editor: In the August 30 issue, Whang-Peng and colleagues report finding the translocation rcp(11;22)(q24;q12) in tumor cells and cell lines from two patients with peripheral neuroepithelioma.1 This observation was of considerable interest since the same chromosomal abnormalities were recently described in Ewing's sarcoma,2,3 a neoplasm easily confused with undifferentiated peripheral neuroectodermal malignant tumors. In the context of these reports, we wish to describe the cytogenetic findings in a malignant peripheral neuroectodermal tumor initially diagnosed as Ewing's sarcoma. An 11-year-old girl presented with a soft-tissue mass involving the left hemithorax and fifth rib. Biopsy revealed a malignant monomorphic poorly…

Original languageEnglish
Pages (from-to)1702-1703
Number of pages2
JournalNew England Journal of Medicine
Volume311
Issue number26
DOIs
Publication statusPublished - Dec 27 1984
Externally publishedYes

Fingerprint

Small Cell Sarcoma
Peripheral Primitive Neuroectodermal Tumors
Ewing's Sarcoma
Ribs
Cytogenetics
Chromosome Aberrations
Neoplasms
Biopsy
Cell Line

ASJC Scopus subject areas

  • Medicine(all)

Cite this

de Chadarevian, J. P., Vekemans, M., Seemayer, T. A., Whang-Peng, J., Triche, T. J., Knutsen, T., ... Israel, M. A. (1984). Reciprocal Translocation in Small-Cell Sarcomas. New England Journal of Medicine, 311(26), 1702-1703. https://doi.org/10.1056/NEJM198412273112618

Reciprocal Translocation in Small-Cell Sarcomas. / de Chadarevian, Jean Pierre; Vekemans, Michel; Seemayer, Thomas A.; Whang-Peng, Jacqueline; Triche, Timothy J.; Knutsen, Turid; Miser, James; Israel, Mark A.

In: New England Journal of Medicine, Vol. 311, No. 26, 27.12.1984, p. 1702-1703.

Research output: Contribution to journalLetter

de Chadarevian, JP, Vekemans, M, Seemayer, TA, Whang-Peng, J, Triche, TJ, Knutsen, T, Miser, J & Israel, MA 1984, 'Reciprocal Translocation in Small-Cell Sarcomas', New England Journal of Medicine, vol. 311, no. 26, pp. 1702-1703. https://doi.org/10.1056/NEJM198412273112618
de Chadarevian JP, Vekemans M, Seemayer TA, Whang-Peng J, Triche TJ, Knutsen T et al. Reciprocal Translocation in Small-Cell Sarcomas. New England Journal of Medicine. 1984 Dec 27;311(26):1702-1703. https://doi.org/10.1056/NEJM198412273112618
de Chadarevian, Jean Pierre ; Vekemans, Michel ; Seemayer, Thomas A. ; Whang-Peng, Jacqueline ; Triche, Timothy J. ; Knutsen, Turid ; Miser, James ; Israel, Mark A. / Reciprocal Translocation in Small-Cell Sarcomas. In: New England Journal of Medicine. 1984 ; Vol. 311, No. 26. pp. 1702-1703.
@article{d2074da9e5d646af85ce88cbd1a38d7b,
title = "Reciprocal Translocation in Small-Cell Sarcomas",
abstract = "To the Editor: In the August 30 issue, Whang-Peng and colleagues report finding the translocation rcp(11;22)(q24;q12) in tumor cells and cell lines from two patients with peripheral neuroepithelioma.1 This observation was of considerable interest since the same chromosomal abnormalities were recently described in Ewing's sarcoma,2,3 a neoplasm easily confused with undifferentiated peripheral neuroectodermal malignant tumors. In the context of these reports, we wish to describe the cytogenetic findings in a malignant peripheral neuroectodermal tumor initially diagnosed as Ewing's sarcoma. An 11-year-old girl presented with a soft-tissue mass involving the left hemithorax and fifth rib. Biopsy revealed a malignant monomorphic poorly…",
author = "{de Chadarevian}, {Jean Pierre} and Michel Vekemans and Seemayer, {Thomas A.} and Jacqueline Whang-Peng and Triche, {Timothy J.} and Turid Knutsen and James Miser and Israel, {Mark A.}",
year = "1984",
month = "12",
day = "27",
doi = "10.1056/NEJM198412273112618",
language = "English",
volume = "311",
pages = "1702--1703",
journal = "New England Journal of Medicine",
issn = "0028-4793",
publisher = "Massachussetts Medical Society",
number = "26",

}

TY - JOUR

T1 - Reciprocal Translocation in Small-Cell Sarcomas

AU - de Chadarevian, Jean Pierre

AU - Vekemans, Michel

AU - Seemayer, Thomas A.

AU - Whang-Peng, Jacqueline

AU - Triche, Timothy J.

AU - Knutsen, Turid

AU - Miser, James

AU - Israel, Mark A.

PY - 1984/12/27

Y1 - 1984/12/27

N2 - To the Editor: In the August 30 issue, Whang-Peng and colleagues report finding the translocation rcp(11;22)(q24;q12) in tumor cells and cell lines from two patients with peripheral neuroepithelioma.1 This observation was of considerable interest since the same chromosomal abnormalities were recently described in Ewing's sarcoma,2,3 a neoplasm easily confused with undifferentiated peripheral neuroectodermal malignant tumors. In the context of these reports, we wish to describe the cytogenetic findings in a malignant peripheral neuroectodermal tumor initially diagnosed as Ewing's sarcoma. An 11-year-old girl presented with a soft-tissue mass involving the left hemithorax and fifth rib. Biopsy revealed a malignant monomorphic poorly…

AB - To the Editor: In the August 30 issue, Whang-Peng and colleagues report finding the translocation rcp(11;22)(q24;q12) in tumor cells and cell lines from two patients with peripheral neuroepithelioma.1 This observation was of considerable interest since the same chromosomal abnormalities were recently described in Ewing's sarcoma,2,3 a neoplasm easily confused with undifferentiated peripheral neuroectodermal malignant tumors. In the context of these reports, we wish to describe the cytogenetic findings in a malignant peripheral neuroectodermal tumor initially diagnosed as Ewing's sarcoma. An 11-year-old girl presented with a soft-tissue mass involving the left hemithorax and fifth rib. Biopsy revealed a malignant monomorphic poorly…

UR - http://www.scopus.com/inward/record.url?scp=0021721929&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021721929&partnerID=8YFLogxK

U2 - 10.1056/NEJM198412273112618

DO - 10.1056/NEJM198412273112618

M3 - Letter

VL - 311

SP - 1702

EP - 1703

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 0028-4793

IS - 26

ER -