Reasons for exclusion of 6820 umbilical cord blood donations in a public cord blood bank

Tso Fu Wang, Shu Hui Wen, Kuo Liang Yang, Shang Hsien Yang, Yun Fan Yang, Chu Yu Chang, Yi Feng Wu, Shu Huey Chen

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background To provide information for umbilical cord blood (UCB) banks to adopt optimal collection strategies and to make UCB banks operate efficiently, we investigated the reasons for exclusion of UCB units in a 3-year recruitment period. Study Design and Methods We analyzed records of the reasons for exclusion of the potential UCB donation from 2004 to 2006 in the Tzu-Chi Cord Blood Bank and compared the results over 3 years. We grouped these reasons for exclusion into five phases, before collection, during delivery, before processing, during processing, and after freezing according to the time sequence and analyzed the reasons at each phase. Results Between 2004 and 2006, there were 10,685 deliveries with the intention of UCB donation. In total, 41.2% of the UCB units were considered eligible for transplantation. The exclusion rates were 93.1, 48.4, and 54.1% in 2004, 2005, and 2006, respectively. We excluded 612 donations from women before their child birth, 133 UCB units during delivery, 80 units before processing, 5010 units during processing, and 421 units after freezing. There were 24 UCB units with unknown reasons of ineligibility. Low UCB weight and low cell count were the first two leading causes of exclusion (48.6 and 30.9%). The prevalence of artificial errors, holiday or transportation problem, low weight, and infant problems decreased year after year. Conclusion The exclusion rate was high at the beginning of our study as in previous studies. Understanding the reasons for UCB exclusion may help to improve the efficiency of UCB banking programs in the future.

Original languageEnglish
Pages (from-to)231-237
Number of pages7
JournalTransfusion
Volume54
Issue number1
DOIs
Publication statusPublished - Jan 2014
Externally publishedYes

Fingerprint

Blood Banks
Blood Donors
Fetal Blood
Freezing
Weights and Measures
Holidays
Cell Count
Transplantation

ASJC Scopus subject areas

  • Hematology
  • Immunology
  • Immunology and Allergy

Cite this

Wang, T. F., Wen, S. H., Yang, K. L., Yang, S. H., Yang, Y. F., Chang, C. Y., ... Chen, S. H. (2014). Reasons for exclusion of 6820 umbilical cord blood donations in a public cord blood bank. Transfusion, 54(1), 231-237. https://doi.org/10.1111/trf.12269

Reasons for exclusion of 6820 umbilical cord blood donations in a public cord blood bank. / Wang, Tso Fu; Wen, Shu Hui; Yang, Kuo Liang; Yang, Shang Hsien; Yang, Yun Fan; Chang, Chu Yu; Wu, Yi Feng; Chen, Shu Huey.

In: Transfusion, Vol. 54, No. 1, 01.2014, p. 231-237.

Research output: Contribution to journalArticle

Wang, TF, Wen, SH, Yang, KL, Yang, SH, Yang, YF, Chang, CY, Wu, YF & Chen, SH 2014, 'Reasons for exclusion of 6820 umbilical cord blood donations in a public cord blood bank', Transfusion, vol. 54, no. 1, pp. 231-237. https://doi.org/10.1111/trf.12269
Wang TF, Wen SH, Yang KL, Yang SH, Yang YF, Chang CY et al. Reasons for exclusion of 6820 umbilical cord blood donations in a public cord blood bank. Transfusion. 2014 Jan;54(1):231-237. https://doi.org/10.1111/trf.12269
Wang, Tso Fu ; Wen, Shu Hui ; Yang, Kuo Liang ; Yang, Shang Hsien ; Yang, Yun Fan ; Chang, Chu Yu ; Wu, Yi Feng ; Chen, Shu Huey. / Reasons for exclusion of 6820 umbilical cord blood donations in a public cord blood bank. In: Transfusion. 2014 ; Vol. 54, No. 1. pp. 231-237.
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