Real-world comparison of drug-eluting and bare-metal stents in superficial femoral artery occlusive disease with trans-Atlantic intersociety consensus B lesions: A 2-year, single-institute study

Fan Chieh Meng, Po Lin Chen, Chiu Yang Lee, Chun Che Shih, I. Ming Chen

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Endovascular stenting has surpassed bypass surgery to become the first-line treatment for superficial femoral artery (SFA) occlusive disease, and various types of stents including bare-metal stents (BMSs), covered stents, and drug-eluting stents (DESs), have been approved for treatment. This retrospective, single-institute study compared the short-term, real-world outcomes of BMSs and DESs for treating SFA occlusive disease. Methods: A retrospective chart review was used to enroll 94 patients who received a DES (n = 24) or BMS (n = 70) between 2009 and 2014. All patients had SFA occlusive disease with critical limb ischemia and an intermediate length of SFA occlusion [Trans-Atlantic Intersociety Consensus (TASC)-II B lesions] and were regularly followed for 2 years. All patient characteristics, procedural details, and outcomes were recorded. Result: The 1-year primary patency rates in the BMS and DES groups were 71.4% and 87.5% (p = 0.169), respectively, and the corresponding 2-year rates were 61.4% and 79.2% (p = 0.139). The target lesion revascularization rate was 38.6% versus 20.8% (p = 0.139), the in-stent restenosis rate was 22.9% versus 0% (p = 0.009), the major limb amputation rate was 4.3% versus 0% (p = 0.568), the peripheral arterial disease-related mortality rate was 8.6% versus 0% (p = 0.332), and the all-cause mortality rate was 11.4% versus 0% (p = 0.109), respectively. Conclusions: The 2-year results revealed higher safety, superior efficacy, and greater clinical benefits of DESs than BMSs for treating TASC-II B SFA occlusive disease. However, more cases and long-term follow-up are warranted.

Original languageEnglish
Pages (from-to)130-136
Number of pages7
JournalActa Cardiologica Sinica
Volume34
Issue number2
DOIs
Publication statusPublished - Mar 1 2018
Externally publishedYes

Keywords

  • Bare-metal stent
  • Drug-eluting stent
  • Superficial femoral artery
  • Trans-Atlantic Intersociety Consensus (TASC)-II B superficial femoral artery lesion

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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