Ratio of early mitral inflow peak velocity to flow propagation velocity predicts training effects of cardiac rehabilitation in patients after acute myocardial infarction

Cheng Chih Chung, Wei Chun Huang, Kuan Rau Chiou, Ko Long Lin, Feng Yu Kuo, Chin Chang Cheng, Shih Hung Hsiao, Chun Peng Liu

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: To use the ratio of early mitral inflow peak velocity (E) to mitral flow propagation velocity (FPV) measured in the early phase of myocardial infarction (early phase E/FPV) to evaluate the training effects of 8 weeks' cardiopulmonary rehabilitation in patients post-myocardial infarction. Design: Single-blinded, randomized control trial. Participants: Eighty-seven patients with acute myocardial infarction who had undergone primary coronary intervention. Methods: Participants were enrolled randomly to either the cardiac rehabilitation or the control group. The rehabilitation group followed an 8-week supervised rehabilitation programme. All patients completed exercise testing and echocardiography at both the beginning and at 8-week follow-up. Results: The value of E/FPV was significantly reduced at 8-week follow-up in the rehabilitation group (p=0.005). After cardiac rehabilitation, the increase in peak VO2 (p=0.002) and cardiac clinical outcome (composition of mortality, cardiac readmission rate, and revascularization rate) (p=0.001) were significantly greater in patients with an early phase E/FPV <1.5 than in patients with early phase E/FPV ≥1.5. There were no significant differences in the increase in peak VO2 and cardiac clinical outcome in patients with early phase E/FPV ≥ 1.5. Conclusion: Early phase E/FPV <1.5 predicts more beneficial effects of cardiac rehabilitation in post-acute myocardial infarction patients who have undergone primary coronary intervention.

Original languageEnglish
Pages (from-to)232-238
Number of pages7
JournalJournal of Rehabilitation Medicine
Volume42
Issue number3
DOIs
Publication statusPublished - Mar 1 2010
Externally publishedYes

Keywords

  • Anaerobic threshold
  • Echocardiography
  • Exercise therapy
  • Flow propagation velocity
  • Myocardial infarction
  • Oxygen consumption
  • Rehabilitation

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

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