Rapid creation of a temporary isolation ward for patients with severe acute respiratory syndrome in Taiwan

Chang Phone Fung, Tsorng Liu Hsieh, Kuang Huan Tan, Chin Hui Loh, Jiunn Sheng Wu, Chien Chung Li, Feng Yee Chang, L. K. Siu, Moh Yun Yen, Lih Shinn Wang, Wing Wai Wong, Wei Fong Kao, Jia Hui Hsu, Ting Hsiang Lin, Fu Yuan Huang, Chen Hsen Lee

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

OBJECTIVES: To rapidly establish a temporary isolation ward to handle an unexpected sudden outbreak of severe acute respiratory syndrome (SARS) and to evaluate the implementation of exposure control measures by healthcare workers (HCWs) for SARS patients. DESIGN: Rapid creation of 60 relatively negative pressure isolation rooms for 196 suspected SARS patients transferred from 19 hospitals and daily temperature recordings of 180 volunteer HCWs from 6 medical centers. SETTING: A military hospital. RESULTS: Of the 196 patients, 34 (17.3%) met the World Health Organization criteria for probable SARS with positive results of serologic testing for SARS-associated coronavirus (SARS-CoV), reverse transcriptase polymerase chain reaction (RT-PCR) from nasopharyngeal or throat swabs for SARS-CoV, or both. Seventy-four patients had suspected SARS based on unprotected exposure to SARS patients; three of them had positive results on RT-PCR but negative serologic results. The remaining 88 patients did not meet the criteria for a probable or suspected SARS diagnosis. Of the 34 patients with probable SARS, 13 were transferred to medical centers to receive mechanical ventilation due to rapid deterioration of chest x-ray results, and three patients died of SARS despite intensive therapy in medical centers. During the study period, one nurse developed probable SARS due to violation of infection control measures, but there was no evidence of cross-transmission to other HCWs. CONCLUSIONS: Despite the use of full personal protection equipment, the facility failed to totally prevent exposures of HCWs to SARS but minimized the risk of nosocomial transmission. Better training and improvements in infection control infrastructure may limit the impact of SARS.

Original languageEnglish
Pages (from-to)1026-1032
Number of pages7
JournalInfection Control and Hospital Epidemiology
Volume25
Issue number12
DOIs
Publication statusPublished - Dec 2004
Externally publishedYes

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Patient Isolation
Severe Acute Respiratory Syndrome
Taiwan
Delivery of Health Care
Infection Control
Reverse Transcriptase Polymerase Chain Reaction
Military Hospitals
Coronavirus

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology

Cite this

Rapid creation of a temporary isolation ward for patients with severe acute respiratory syndrome in Taiwan. / Fung, Chang Phone; Hsieh, Tsorng Liu; Tan, Kuang Huan; Loh, Chin Hui; Wu, Jiunn Sheng; Li, Chien Chung; Chang, Feng Yee; Siu, L. K.; Yen, Moh Yun; Wang, Lih Shinn; Wong, Wing Wai; Kao, Wei Fong; Hsu, Jia Hui; Lin, Ting Hsiang; Huang, Fu Yuan; Lee, Chen Hsen.

In: Infection Control and Hospital Epidemiology, Vol. 25, No. 12, 12.2004, p. 1026-1032.

Research output: Contribution to journalArticle

Fung, CP, Hsieh, TL, Tan, KH, Loh, CH, Wu, JS, Li, CC, Chang, FY, Siu, LK, Yen, MY, Wang, LS, Wong, WW, Kao, WF, Hsu, JH, Lin, TH, Huang, FY & Lee, CH 2004, 'Rapid creation of a temporary isolation ward for patients with severe acute respiratory syndrome in Taiwan', Infection Control and Hospital Epidemiology, vol. 25, no. 12, pp. 1026-1032. https://doi.org/10.1086/502339
Fung, Chang Phone ; Hsieh, Tsorng Liu ; Tan, Kuang Huan ; Loh, Chin Hui ; Wu, Jiunn Sheng ; Li, Chien Chung ; Chang, Feng Yee ; Siu, L. K. ; Yen, Moh Yun ; Wang, Lih Shinn ; Wong, Wing Wai ; Kao, Wei Fong ; Hsu, Jia Hui ; Lin, Ting Hsiang ; Huang, Fu Yuan ; Lee, Chen Hsen. / Rapid creation of a temporary isolation ward for patients with severe acute respiratory syndrome in Taiwan. In: Infection Control and Hospital Epidemiology. 2004 ; Vol. 25, No. 12. pp. 1026-1032.
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abstract = "OBJECTIVES: To rapidly establish a temporary isolation ward to handle an unexpected sudden outbreak of severe acute respiratory syndrome (SARS) and to evaluate the implementation of exposure control measures by healthcare workers (HCWs) for SARS patients. DESIGN: Rapid creation of 60 relatively negative pressure isolation rooms for 196 suspected SARS patients transferred from 19 hospitals and daily temperature recordings of 180 volunteer HCWs from 6 medical centers. SETTING: A military hospital. RESULTS: Of the 196 patients, 34 (17.3{\%}) met the World Health Organization criteria for probable SARS with positive results of serologic testing for SARS-associated coronavirus (SARS-CoV), reverse transcriptase polymerase chain reaction (RT-PCR) from nasopharyngeal or throat swabs for SARS-CoV, or both. Seventy-four patients had suspected SARS based on unprotected exposure to SARS patients; three of them had positive results on RT-PCR but negative serologic results. The remaining 88 patients did not meet the criteria for a probable or suspected SARS diagnosis. Of the 34 patients with probable SARS, 13 were transferred to medical centers to receive mechanical ventilation due to rapid deterioration of chest x-ray results, and three patients died of SARS despite intensive therapy in medical centers. During the study period, one nurse developed probable SARS due to violation of infection control measures, but there was no evidence of cross-transmission to other HCWs. CONCLUSIONS: Despite the use of full personal protection equipment, the facility failed to totally prevent exposures of HCWs to SARS but minimized the risk of nosocomial transmission. Better training and improvements in infection control infrastructure may limit the impact of SARS.",
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AU - Fung, Chang Phone

AU - Hsieh, Tsorng Liu

AU - Tan, Kuang Huan

AU - Loh, Chin Hui

AU - Wu, Jiunn Sheng

AU - Li, Chien Chung

AU - Chang, Feng Yee

AU - Siu, L. K.

AU - Yen, Moh Yun

AU - Wang, Lih Shinn

AU - Wong, Wing Wai

AU - Kao, Wei Fong

AU - Hsu, Jia Hui

AU - Lin, Ting Hsiang

AU - Huang, Fu Yuan

AU - Lee, Chen Hsen

PY - 2004/12

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N2 - OBJECTIVES: To rapidly establish a temporary isolation ward to handle an unexpected sudden outbreak of severe acute respiratory syndrome (SARS) and to evaluate the implementation of exposure control measures by healthcare workers (HCWs) for SARS patients. DESIGN: Rapid creation of 60 relatively negative pressure isolation rooms for 196 suspected SARS patients transferred from 19 hospitals and daily temperature recordings of 180 volunteer HCWs from 6 medical centers. SETTING: A military hospital. RESULTS: Of the 196 patients, 34 (17.3%) met the World Health Organization criteria for probable SARS with positive results of serologic testing for SARS-associated coronavirus (SARS-CoV), reverse transcriptase polymerase chain reaction (RT-PCR) from nasopharyngeal or throat swabs for SARS-CoV, or both. Seventy-four patients had suspected SARS based on unprotected exposure to SARS patients; three of them had positive results on RT-PCR but negative serologic results. The remaining 88 patients did not meet the criteria for a probable or suspected SARS diagnosis. Of the 34 patients with probable SARS, 13 were transferred to medical centers to receive mechanical ventilation due to rapid deterioration of chest x-ray results, and three patients died of SARS despite intensive therapy in medical centers. During the study period, one nurse developed probable SARS due to violation of infection control measures, but there was no evidence of cross-transmission to other HCWs. CONCLUSIONS: Despite the use of full personal protection equipment, the facility failed to totally prevent exposures of HCWs to SARS but minimized the risk of nosocomial transmission. Better training and improvements in infection control infrastructure may limit the impact of SARS.

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