Quantitative evaluation of thrombosis by electrochemical methodology

Chun Che Shih, Chun Ming Shih, Yea Yang Su, Lin Hui Julie Su, Mau Song Chang, Shing Jong Lin

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Electrochemical reactions between blood and metal electrodes have been studied since 1928. Little is known about the actual current density induced during the reaction. In this study, an in situ continuous monitoring method was developed to detect the progress of thrombosis on an oxidized 316L stainless steel coil was deployed inside the artery. Three stages of current density were observed on a 316L wire passivated with polycrystalline oxide film. In contrast, no significant current density was detected for a wire passivated with amorphous oxide film. Results showed that this in situ electrochemical monitoring method is sensitive to the passivated film on the stainless steel coil and could provide efficient and reliable information on the control of thrombosis on cardiovascular devices.

Original languageEnglish
Pages (from-to)103-109
Number of pages7
JournalThrombosis Research
Volume111
Issue number1-2
DOIs
Publication statusPublished - 2003

Keywords

  • Amorphous oxide
  • Current density
  • Electrochemical
  • Polycrystalline oxide
  • Thrombosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Hematology

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