Quantitative analysis of breast echotexture patterns in automated breast ultrasound images

Ruey Feng Chang, Yu Ling Hou, Chung Ming Lo, Chiun Sheng Huang, Jeon Hor Chen, Won Hwa Kim, Jung Min Chang, Min Sun Bae, Woo Kyung Moon

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Purpose: Breast tissue composition is considered to be associated with breast cancer risk. This study aimed to develop a computer-aided classification (CAC) system to automatically classify echotexture patterns as heterogeneous or homogeneous using automated breast ultrasound (ABUS) images. Methods: A CAC system was proposed that can recognize breast echotexture patterns in ABUS images. For each case, the echotexture pattern was assessed by two expert radiologists and classified as heterogeneous or homogeneous. After neutrosophic image transformation and fuzzy c-mean clusterings, the lower and upper boundaries of the fibroglandular tissues were defined. Then, the number of hypoechoic regions and histogram features were extracted from the fibroglandular tissues, and the support vector machine model with the leave-one-out cross-validation method was utilized as the classifier. The authors' database included a total of 208 ABUS images of the breasts of 104 females. Results: The accuracies of the proposed system for the classification of heterogeneous and homogeneous echotexture patterns were 93.48% (43/46) and 92.59% (150/162), respectively, with an overall Az (area under the receiver operating characteristic curve) of 0.9786. The agreement between the radiologists and the proposed system was almost perfect, with a kappa value of 0.814. Conclusions: The use of ABUS and the proposed method can provide quantitative information on the echotexture patterns of the breast and can be used to evaluate whether breast echotexture patterns are associated with breast cancer risk in the future.

Original languageEnglish
Pages (from-to)4566-4578
Number of pages13
JournalMedical Physics
Volume42
Issue number8
DOIs
Publication statusPublished - Aug 1 2015
Externally publishedYes

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Keywords

  • automated breast ultrasound
  • breast cancer
  • computer-aided classification
  • echotexture
  • mammographic density

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

Cite this

Chang, R. F., Hou, Y. L., Lo, C. M., Huang, C. S., Chen, J. H., Kim, W. H., Chang, J. M., Bae, M. S., & Moon, W. K. (2015). Quantitative analysis of breast echotexture patterns in automated breast ultrasound images. Medical Physics, 42(8), 4566-4578. https://doi.org/10.1118/1.4923754