Quality of life in patients of nasopharyngeal carcinoma: Validation of the Taiwan Chinese version of the EORTC QLQ-C30 and the EORTC QLQ-H&N35

Wei Chu Chie, R. L. Hong, C. C. Lai, L. L. Ting, M. M. Hsu

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

The authors followed the guidelines of translation and pilot testing of the EORTC QLQ-C30 and EORTC-QLQ-H&N35 questionnaires. The questionnaires were given to 50 nasopharyngeal carcinoma patients under active treatment and 50 under follow-up at our institution from November 2000 to June 2001. A retest was conducted 2 weeks after the first interview/form completion for the follow-up group. The intraclass correlation coefficients of the two questionnaires were moderate to high in the follow-up group. Cronbach's α coefficients of all scales of the two questionnaires were ≥0.70 except that of cognitive functioning. Correlation of scales measuring similar dimensions of the QLQ-C30 and the SF-36 were moderate to high, while that of the QLQ-H&N35 and the QLQ-C30 and the SF-36 were moderate to low. Patients in the active treatment group had more serious acute problems due to disease and chemotherapy. Patients in the follow-up group had more serious chronic problems due to radiation therapy. We concluded that the Taiwan Chinese version of the EORTC QLQ-C30 and the EORTC QLQ-H&N35 had moderate to high test-retest reliability, high internal consistency in most scales, and could show the expected differences between patients in active treatment and follow-up group.

Original languageEnglish
Pages (from-to)93-98
Number of pages6
JournalQuality of Life Research
Volume12
Issue number1
DOIs
Publication statusPublished - Feb 1 2003
Externally publishedYes

Keywords

  • Nasopharyngeal carcinoma
  • Quality of life
  • The EORTC QLQ-C30
  • The EORTC QLQ-H&N35

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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