Quality of life in adults with congenital heart disease

Biopsychosocial determinants and sex-related differences

Chun An Chen, Shih Cheng Liao, Jou Kou Wang, Chung I. Chang, Ing Sh Chiu, Yih Sharng Chen, Chun Wei Lu, Ming Tai Lin, Hsin Hui Chiu, Shuenn Nan Chiu, Yu Chuan Hua, Hung Chi Lue, Mei Hwan Wu

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Objectives: To assess the quality of life (QoL) in adults with congenital heart disease (ACHD) and to explore the sex-related differences and biopsychosocial determinants in an Asian cohort. Design: Prospective cross-sectional clinical study. Setting: One tertiary medical centre in Taiwan. Patients and methods: The QoL of ACHD (≥20 years) was investigated using the Taiwanese version of the QoL questionnaire designed by the WHO, which assesses four domains of QoL (physical, psychological, social and environmental). Personality, psychological distress and family support were assessed using the Maudsley Personality Inventory, Brief Symptom Rating Scale, and the Family APGAR score, respectively. Results: A total of 289 patients (age 33.2±10.6 years; 36% men) were studied. ACHD women had significantly lower QoL scores in the physical and psychological domains compared to the age-matched general population, whereas no differences were observed between ACHD men and the general population. Multivariate analysis showed that female gender was associated with poorer physical QoL; the sex difference in the psychological QoL was mediated by psychological distress. Interaction analysis showed that the effect of family support on the psychological domain of QoL may be different by sex. The determinants of QoL varied between different domains. Extroversion personality trait, psychological distress and family support were common determinants of most domains of QoL. Conclusions: In ACHD, female gender was associated with poor physical and psychological QoL. The common denominators for QoL were primarily personality trait, psychological distress and family support, but not disease severity.

Original languageEnglish
Pages (from-to)38-43
Number of pages6
JournalHeart
Volume97
Issue number1
DOIs
Publication statusPublished - Jan 2011
Externally publishedYes

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Sex Characteristics
Heart Diseases
Quality of Life
Psychology
Personality
Personality Inventory
Taiwan
Population
Multivariate Analysis
Cross-Sectional Studies

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Chen, C. A., Liao, S. C., Wang, J. K., Chang, C. I., Chiu, I. S., Chen, Y. S., ... Wu, M. H. (2011). Quality of life in adults with congenital heart disease: Biopsychosocial determinants and sex-related differences. Heart, 97(1), 38-43. https://doi.org/10.1136/hrt.2010.200709

Quality of life in adults with congenital heart disease : Biopsychosocial determinants and sex-related differences. / Chen, Chun An; Liao, Shih Cheng; Wang, Jou Kou; Chang, Chung I.; Chiu, Ing Sh; Chen, Yih Sharng; Lu, Chun Wei; Lin, Ming Tai; Chiu, Hsin Hui; Chiu, Shuenn Nan; Hua, Yu Chuan; Lue, Hung Chi; Wu, Mei Hwan.

In: Heart, Vol. 97, No. 1, 01.2011, p. 38-43.

Research output: Contribution to journalArticle

Chen, CA, Liao, SC, Wang, JK, Chang, CI, Chiu, IS, Chen, YS, Lu, CW, Lin, MT, Chiu, HH, Chiu, SN, Hua, YC, Lue, HC & Wu, MH 2011, 'Quality of life in adults with congenital heart disease: Biopsychosocial determinants and sex-related differences', Heart, vol. 97, no. 1, pp. 38-43. https://doi.org/10.1136/hrt.2010.200709
Chen, Chun An ; Liao, Shih Cheng ; Wang, Jou Kou ; Chang, Chung I. ; Chiu, Ing Sh ; Chen, Yih Sharng ; Lu, Chun Wei ; Lin, Ming Tai ; Chiu, Hsin Hui ; Chiu, Shuenn Nan ; Hua, Yu Chuan ; Lue, Hung Chi ; Wu, Mei Hwan. / Quality of life in adults with congenital heart disease : Biopsychosocial determinants and sex-related differences. In: Heart. 2011 ; Vol. 97, No. 1. pp. 38-43.
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abstract = "Objectives: To assess the quality of life (QoL) in adults with congenital heart disease (ACHD) and to explore the sex-related differences and biopsychosocial determinants in an Asian cohort. Design: Prospective cross-sectional clinical study. Setting: One tertiary medical centre in Taiwan. Patients and methods: The QoL of ACHD (≥20 years) was investigated using the Taiwanese version of the QoL questionnaire designed by the WHO, which assesses four domains of QoL (physical, psychological, social and environmental). Personality, psychological distress and family support were assessed using the Maudsley Personality Inventory, Brief Symptom Rating Scale, and the Family APGAR score, respectively. Results: A total of 289 patients (age 33.2±10.6 years; 36{\%} men) were studied. ACHD women had significantly lower QoL scores in the physical and psychological domains compared to the age-matched general population, whereas no differences were observed between ACHD men and the general population. Multivariate analysis showed that female gender was associated with poorer physical QoL; the sex difference in the psychological QoL was mediated by psychological distress. Interaction analysis showed that the effect of family support on the psychological domain of QoL may be different by sex. The determinants of QoL varied between different domains. Extroversion personality trait, psychological distress and family support were common determinants of most domains of QoL. Conclusions: In ACHD, female gender was associated with poor physical and psychological QoL. The common denominators for QoL were primarily personality trait, psychological distress and family support, but not disease severity.",
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AU - Chiu, Ing Sh

AU - Chen, Yih Sharng

AU - Lu, Chun Wei

AU - Lin, Ming Tai

AU - Chiu, Hsin Hui

AU - Chiu, Shuenn Nan

AU - Hua, Yu Chuan

AU - Lue, Hung Chi

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