Q-ball imaging with PROPELLER EPI acquisition

Ming Chung Chou, Teng Yi Huang, Hsiao Wen Chung, Tsyh Jyi Hsieh, Hing Chiu Chang, Cheng Yu Chen

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Q-ball imaging (QBI) is an imaging technique that is capable of resolving intravoxel fiber crossings; however, the signal readout based on echo-planar imaging (EPI) introduces geometric distortions in the presence of susceptibility gradients. This study proposes an imaging technique that reduces susceptibility distortions in QBI by short-axis PROPELLER EPI acquisition. Conventional QBI and PROPELLER QBI data were acquired from two 3T MR scans of the brains of five healthy subjects. Prior to the PROPELLER reconstruction, residual distortions in single-blade low-resolution b0 and diffusion-weighted images (DWIs) were minimized by linear affine and nonlinear diffeomorphic demon registrations. Subsequently, the PROPELLER keyhole reconstruction was applied to the corrected DWIs to obtain high-resolution PROPELLER DWIs. The generalized fractional anisotropy and orientation distribution function maps contained fewer distortions in PROPELLER QBI than in conventional QBI, and the fiber tracts more closely matched the brain anatomy depicted by turbo spin-echo (TSE) T2-weighted imaging (T2WI). Furthermore, for fixed TE, PROPELLER QBI enabled a shorter scan time than conventional QBI. We conclude that PROPELLER QBI can reduce susceptibility distortions without lengthening the acquisition time and is suitable for tracing neuronal fiber tracts in the human brain.

Original languageEnglish
Pages (from-to)1723-1732
Number of pages10
JournalNMR in Biomedicine
Volume26
Issue number12
DOIs
Publication statusPublished - Dec 2013
Externally publishedYes

Fingerprint

Echo-Planar Imaging
Imaging techniques
Brain
Anisotropy
Anatomy
Healthy Volunteers
Fibers

Keywords

  • Fiber tracking
  • GFA
  • Keyhole
  • ODF
  • PROPELLER
  • QBI

ASJC Scopus subject areas

  • Spectroscopy
  • Molecular Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Chou, M. C., Huang, T. Y., Chung, H. W., Hsieh, T. J., Chang, H. C., & Chen, C. Y. (2013). Q-ball imaging with PROPELLER EPI acquisition. NMR in Biomedicine, 26(12), 1723-1732. https://doi.org/10.1002/nbm.3009

Q-ball imaging with PROPELLER EPI acquisition. / Chou, Ming Chung; Huang, Teng Yi; Chung, Hsiao Wen; Hsieh, Tsyh Jyi; Chang, Hing Chiu; Chen, Cheng Yu.

In: NMR in Biomedicine, Vol. 26, No. 12, 12.2013, p. 1723-1732.

Research output: Contribution to journalArticle

Chou, MC, Huang, TY, Chung, HW, Hsieh, TJ, Chang, HC & Chen, CY 2013, 'Q-ball imaging with PROPELLER EPI acquisition', NMR in Biomedicine, vol. 26, no. 12, pp. 1723-1732. https://doi.org/10.1002/nbm.3009
Chou MC, Huang TY, Chung HW, Hsieh TJ, Chang HC, Chen CY. Q-ball imaging with PROPELLER EPI acquisition. NMR in Biomedicine. 2013 Dec;26(12):1723-1732. https://doi.org/10.1002/nbm.3009
Chou, Ming Chung ; Huang, Teng Yi ; Chung, Hsiao Wen ; Hsieh, Tsyh Jyi ; Chang, Hing Chiu ; Chen, Cheng Yu. / Q-ball imaging with PROPELLER EPI acquisition. In: NMR in Biomedicine. 2013 ; Vol. 26, No. 12. pp. 1723-1732.
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