Pyogenic liver abscess treated by percutaneous catheter drainage: MDCT measurement for treatment outcome

Wen I. Liao, Shih Hung Tsai, Chih Yung Yu, Guo Shu Huang, Yen Yue Lin, Ching Wang Hsu, Hsian He Hsu, Wei Chou Chang

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Objective: To analyze multidetector computed tomographic (MDCT) parameters in patients with pyogenic liver abscess (PLA), and to identify which parameters can be predicted percutaneous catheter drainage (PCD) treatment outcome. Materials and methods: Clinical, laboratory and MDCT findings of 175 patients with PLA who had undergone PCD were retrospectively reviewed. All abscesses shown on MDCT were evaluated for size, margin, attenuation values, location, number of large (>3 cm) abscesses, presence of a cystic component, presence of gas, and the shortest length to the liver capsule. Univariate and multivariate analyses of the MDCT parameters that affect PCD treatment outcome was performed. For continuous data of MDCT parameters (abscess size and the shortest length), we used receiver-operating-characteristic (ROC) curve to determine the optimal cut-off values. Results: PCD was failed in 32 patients and the overall failure rate was 18.28%. Multivariate analysis revealed that PCD failure was predicted by the presence of gas (odds ratio [OR], 42.67), a large abscess (OR 1.21), low minimal attenuation values (OR 1.02), wide range of attenuation values (OR 1.01), a shorter length to the liver capsule (OR 0.09) and lack of a cystic component (OR 0.09) of the PLA. ROC curve showed that the shortest length less than 0.25 cm and an abscess size greater than 7.3 cm were the optimal cut-off values predicting PCD treatment failure. Conclusion: Among these MDCT parameters, gas formation within PLA was the most important predictor for PCD failure. Surgical intervention might be considered early in high-risk patients of PCD failure.

Original languageEnglish
Pages (from-to)609-615
Number of pages7
JournalEuropean Journal of Radiology
Volume81
Issue number4
DOIs
Publication statusPublished - Apr 2012
Externally publishedYes

Fingerprint

Pyogenic Liver Abscess
Drainage
Catheters
Abscess
Odds Ratio
Gases
ROC Curve
Capsules
Multivariate Analysis
Liver
Treatment Failure

Keywords

  • CT attenuation
  • Gas
  • Multidetector-row computed tomography
  • Percutaneous catheter drainage
  • Pyogenic liver abscess

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Pyogenic liver abscess treated by percutaneous catheter drainage : MDCT measurement for treatment outcome. / Liao, Wen I.; Tsai, Shih Hung; Yu, Chih Yung; Huang, Guo Shu; Lin, Yen Yue; Hsu, Ching Wang; Hsu, Hsian He; Chang, Wei Chou.

In: European Journal of Radiology, Vol. 81, No. 4, 04.2012, p. 609-615.

Research output: Contribution to journalArticle

Liao, Wen I. ; Tsai, Shih Hung ; Yu, Chih Yung ; Huang, Guo Shu ; Lin, Yen Yue ; Hsu, Ching Wang ; Hsu, Hsian He ; Chang, Wei Chou. / Pyogenic liver abscess treated by percutaneous catheter drainage : MDCT measurement for treatment outcome. In: European Journal of Radiology. 2012 ; Vol. 81, No. 4. pp. 609-615.
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AU - Tsai, Shih Hung

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AU - Huang, Guo Shu

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AU - Hsu, Ching Wang

AU - Hsu, Hsian He

AU - Chang, Wei Chou

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N2 - Objective: To analyze multidetector computed tomographic (MDCT) parameters in patients with pyogenic liver abscess (PLA), and to identify which parameters can be predicted percutaneous catheter drainage (PCD) treatment outcome. Materials and methods: Clinical, laboratory and MDCT findings of 175 patients with PLA who had undergone PCD were retrospectively reviewed. All abscesses shown on MDCT were evaluated for size, margin, attenuation values, location, number of large (>3 cm) abscesses, presence of a cystic component, presence of gas, and the shortest length to the liver capsule. Univariate and multivariate analyses of the MDCT parameters that affect PCD treatment outcome was performed. For continuous data of MDCT parameters (abscess size and the shortest length), we used receiver-operating-characteristic (ROC) curve to determine the optimal cut-off values. Results: PCD was failed in 32 patients and the overall failure rate was 18.28%. Multivariate analysis revealed that PCD failure was predicted by the presence of gas (odds ratio [OR], 42.67), a large abscess (OR 1.21), low minimal attenuation values (OR 1.02), wide range of attenuation values (OR 1.01), a shorter length to the liver capsule (OR 0.09) and lack of a cystic component (OR 0.09) of the PLA. ROC curve showed that the shortest length less than 0.25 cm and an abscess size greater than 7.3 cm were the optimal cut-off values predicting PCD treatment failure. Conclusion: Among these MDCT parameters, gas formation within PLA was the most important predictor for PCD failure. Surgical intervention might be considered early in high-risk patients of PCD failure.

AB - Objective: To analyze multidetector computed tomographic (MDCT) parameters in patients with pyogenic liver abscess (PLA), and to identify which parameters can be predicted percutaneous catheter drainage (PCD) treatment outcome. Materials and methods: Clinical, laboratory and MDCT findings of 175 patients with PLA who had undergone PCD were retrospectively reviewed. All abscesses shown on MDCT were evaluated for size, margin, attenuation values, location, number of large (>3 cm) abscesses, presence of a cystic component, presence of gas, and the shortest length to the liver capsule. Univariate and multivariate analyses of the MDCT parameters that affect PCD treatment outcome was performed. For continuous data of MDCT parameters (abscess size and the shortest length), we used receiver-operating-characteristic (ROC) curve to determine the optimal cut-off values. Results: PCD was failed in 32 patients and the overall failure rate was 18.28%. Multivariate analysis revealed that PCD failure was predicted by the presence of gas (odds ratio [OR], 42.67), a large abscess (OR 1.21), low minimal attenuation values (OR 1.02), wide range of attenuation values (OR 1.01), a shorter length to the liver capsule (OR 0.09) and lack of a cystic component (OR 0.09) of the PLA. ROC curve showed that the shortest length less than 0.25 cm and an abscess size greater than 7.3 cm were the optimal cut-off values predicting PCD treatment failure. Conclusion: Among these MDCT parameters, gas formation within PLA was the most important predictor for PCD failure. Surgical intervention might be considered early in high-risk patients of PCD failure.

KW - CT attenuation

KW - Gas

KW - Multidetector-row computed tomography

KW - Percutaneous catheter drainage

KW - Pyogenic liver abscess

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