Abstract

Sleep disorders may pose a risk to workers in the workplace. We aimed to investigate the associations between metal fume fine particulate matter (PM2.5) and sleep quality in workers. We assessed the effects of personal exposure to metal fume PM2.5 on lung functions, urinary biomarkers, and sleep quality in shipyard welding workers. In total, 96 welding workers and 54 office workers were recruited in the present study; office workers were exposed to 82.1 ± 94.1 μg/m3 PM2.5 and welding workers were exposed to 2166.5 ± 3149.1 μg/m3. Welding workers had significantly lower levels of FEV25-75 than office workers (p < 0.05). An increase in 1 μg/m3 PM2.5 was associated with a decrease of 0.003 ng/mL in urinary serotonin (95% CI = -0.007-0.000, p < 0.05) in all workers and with a decrease of 0.001 ng/mL in serotonin (95% CI = -0.004-0.002, p < 0.05) in welding workers, but these were not observed in office workers. There was no significant association of PM2.5 with urinary cortisol observed in any workers. Urinary serotonin was associated with urinary Cu, Mn, Co, Ni, Cd, and Pb. Urinary cortisol was associated with Cu, Mn, Co, Ni, Cd, and Pb. Sixteen subjects were randomly selected from each of the office and welding workers for personal monitoring of sleep quality using a wearable device. We observed that welding workers had greater awake times than did office workers (p < 0.05). Our study observed that exposure to heavy metals in metal fume PM2.5 may disrupt sleep quality in welding workers.

Original languageEnglish
Pages (from-to)523-532
JournalEnvironmental Pollution
Volume232
DOIs
Publication statusPublished - Jan 2018

Fingerprint

Welding
Fumes
Particulate Matter
Shipyards
Sleep
Metals
Lung
Cortisol
Serotonin
Hydrocortisone
Polysomnography
Biomarkers
Heavy Metals
Workplace
Heavy metals
Association reactions
Equipment and Supplies
Monitoring

Keywords

  • Cortisol
  • Lung function
  • PM
  • Serotonin
  • Wearable device

ASJC Scopus subject areas

  • Toxicology
  • Pollution
  • Health, Toxicology and Mutagenesis

Cite this

Pulmonary exposure to metal fume particulate matter cause sleep disturbances in shipyard welders. / Chuang, Hsiao Chi; Su, Ting Yao; Chuang, Kai Jen; Hsiao, Ta Chih; Lin, Hong Ling; Hsu, Yuan Ting; Pan, Chih Hong; Lee, Kang Yun; Ho, Shu Chuan; Lai, Ching Huang.

In: Environmental Pollution, Vol. 232, 01.2018, p. 523-532.

Research output: Contribution to journalArticle

Chuang, Hsiao Chi ; Su, Ting Yao ; Chuang, Kai Jen ; Hsiao, Ta Chih ; Lin, Hong Ling ; Hsu, Yuan Ting ; Pan, Chih Hong ; Lee, Kang Yun ; Ho, Shu Chuan ; Lai, Ching Huang. / Pulmonary exposure to metal fume particulate matter cause sleep disturbances in shipyard welders. In: Environmental Pollution. 2018 ; Vol. 232. pp. 523-532.
@article{38e23fd910ea4b58839de8ba754bbaed,
title = "Pulmonary exposure to metal fume particulate matter cause sleep disturbances in shipyard welders",
abstract = "Sleep disorders may pose a risk to workers in the workplace. We aimed to investigate the associations between metal fume fine particulate matter (PM2.5) and sleep quality in workers. We assessed the effects of personal exposure to metal fume PM2.5 on lung functions, urinary biomarkers, and sleep quality in shipyard welding workers. In total, 96 welding workers and 54 office workers were recruited in the present study; office workers were exposed to 82.1 ± 94.1 μg/m3 PM2.5 and welding workers were exposed to 2166.5 ± 3149.1 μg/m3. Welding workers had significantly lower levels of FEV25-75 than office workers (p < 0.05). An increase in 1 μg/m3 PM2.5 was associated with a decrease of 0.003 ng/mL in urinary serotonin (95{\%} CI = -0.007-0.000, p < 0.05) in all workers and with a decrease of 0.001 ng/mL in serotonin (95{\%} CI = -0.004-0.002, p < 0.05) in welding workers, but these were not observed in office workers. There was no significant association of PM2.5 with urinary cortisol observed in any workers. Urinary serotonin was associated with urinary Cu, Mn, Co, Ni, Cd, and Pb. Urinary cortisol was associated with Cu, Mn, Co, Ni, Cd, and Pb. Sixteen subjects were randomly selected from each of the office and welding workers for personal monitoring of sleep quality using a wearable device. We observed that welding workers had greater awake times than did office workers (p < 0.05). Our study observed that exposure to heavy metals in metal fume PM2.5 may disrupt sleep quality in welding workers.",
keywords = "Cortisol, Lung function, PM, Serotonin, Wearable device",
author = "Chuang, {Hsiao Chi} and Su, {Ting Yao} and Chuang, {Kai Jen} and Hsiao, {Ta Chih} and Lin, {Hong Ling} and Hsu, {Yuan Ting} and Pan, {Chih Hong} and Lee, {Kang Yun} and Ho, {Shu Chuan} and Lai, {Ching Huang}",
year = "2018",
month = "1",
doi = "10.1016/j.envpol.2017.09.082",
language = "English",
volume = "232",
pages = "523--532",
journal = "Environmental Pollution",
issn = "0269-7491",
publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Pulmonary exposure to metal fume particulate matter cause sleep disturbances in shipyard welders

AU - Chuang, Hsiao Chi

AU - Su, Ting Yao

AU - Chuang, Kai Jen

AU - Hsiao, Ta Chih

AU - Lin, Hong Ling

AU - Hsu, Yuan Ting

AU - Pan, Chih Hong

AU - Lee, Kang Yun

AU - Ho, Shu Chuan

AU - Lai, Ching Huang

PY - 2018/1

Y1 - 2018/1

N2 - Sleep disorders may pose a risk to workers in the workplace. We aimed to investigate the associations between metal fume fine particulate matter (PM2.5) and sleep quality in workers. We assessed the effects of personal exposure to metal fume PM2.5 on lung functions, urinary biomarkers, and sleep quality in shipyard welding workers. In total, 96 welding workers and 54 office workers were recruited in the present study; office workers were exposed to 82.1 ± 94.1 μg/m3 PM2.5 and welding workers were exposed to 2166.5 ± 3149.1 μg/m3. Welding workers had significantly lower levels of FEV25-75 than office workers (p < 0.05). An increase in 1 μg/m3 PM2.5 was associated with a decrease of 0.003 ng/mL in urinary serotonin (95% CI = -0.007-0.000, p < 0.05) in all workers and with a decrease of 0.001 ng/mL in serotonin (95% CI = -0.004-0.002, p < 0.05) in welding workers, but these were not observed in office workers. There was no significant association of PM2.5 with urinary cortisol observed in any workers. Urinary serotonin was associated with urinary Cu, Mn, Co, Ni, Cd, and Pb. Urinary cortisol was associated with Cu, Mn, Co, Ni, Cd, and Pb. Sixteen subjects were randomly selected from each of the office and welding workers for personal monitoring of sleep quality using a wearable device. We observed that welding workers had greater awake times than did office workers (p < 0.05). Our study observed that exposure to heavy metals in metal fume PM2.5 may disrupt sleep quality in welding workers.

AB - Sleep disorders may pose a risk to workers in the workplace. We aimed to investigate the associations between metal fume fine particulate matter (PM2.5) and sleep quality in workers. We assessed the effects of personal exposure to metal fume PM2.5 on lung functions, urinary biomarkers, and sleep quality in shipyard welding workers. In total, 96 welding workers and 54 office workers were recruited in the present study; office workers were exposed to 82.1 ± 94.1 μg/m3 PM2.5 and welding workers were exposed to 2166.5 ± 3149.1 μg/m3. Welding workers had significantly lower levels of FEV25-75 than office workers (p < 0.05). An increase in 1 μg/m3 PM2.5 was associated with a decrease of 0.003 ng/mL in urinary serotonin (95% CI = -0.007-0.000, p < 0.05) in all workers and with a decrease of 0.001 ng/mL in serotonin (95% CI = -0.004-0.002, p < 0.05) in welding workers, but these were not observed in office workers. There was no significant association of PM2.5 with urinary cortisol observed in any workers. Urinary serotonin was associated with urinary Cu, Mn, Co, Ni, Cd, and Pb. Urinary cortisol was associated with Cu, Mn, Co, Ni, Cd, and Pb. Sixteen subjects were randomly selected from each of the office and welding workers for personal monitoring of sleep quality using a wearable device. We observed that welding workers had greater awake times than did office workers (p < 0.05). Our study observed that exposure to heavy metals in metal fume PM2.5 may disrupt sleep quality in welding workers.

KW - Cortisol

KW - Lung function

KW - PM

KW - Serotonin

KW - Wearable device

UR - http://www.scopus.com/inward/record.url?scp=85030788940&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85030788940&partnerID=8YFLogxK

U2 - 10.1016/j.envpol.2017.09.082

DO - 10.1016/j.envpol.2017.09.082

M3 - Article

VL - 232

SP - 523

EP - 532

JO - Environmental Pollution

JF - Environmental Pollution

SN - 0269-7491

ER -