Pulmonary arteriovenous malformation of Osler-Weber-Rendu syndrome diagnosed by endobronchial ultrasound

Chih Hsi Kuo, Chun Hua Wang, Han Pin Kuo

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Osler-Weber-Rendu syndrome is a disease of hereditary telangiectasia with involvement of multiple visceral organs. Pulmonary arteriovenous malformation (AVM) is a frequent clinical manifestation, that may mimic pulmonary mass. In this report, endobronchial ultrasound (EBUS) was used in a 64-year-old woman with Osler-Weber-Rendu syndrome who had a solitary pulmonary mass associated with clinical evidence of a right-to-left shunt and was able to detect a pulsating hypoechoic mass connected to the right pulmonary artery suggesting of pulmonary AVM. Following magnetic resonance angiogram and chest CT as well as noting multiple telangiectasis on her skin and considering a strong family history, Osler-Weber-Rendu syndrome was confirmed. Exercise intolerance and desaturation improved after surgical resection of the pulmonary AVM. The echoic findings were correlated to the pathological features. EBUS can be used as a good diagnostic tool for determining the nature of peripheral lung lesions such as in this case, and EBUS may be of practical tool to investigate a lung mass when a vascular component is suspected.

Original languageEnglish
Pages (from-to)295-298
Number of pages4
JournalRespirology
Volume12
Issue number2
DOIs
Publication statusPublished - Mar 1 2007
Externally publishedYes

Fingerprint

Hereditary Hemorrhagic Telangiectasia
Arteriovenous Malformations
Lung
Telangiectasis
Inborn Genetic Diseases
Pulmonary Artery
Blood Vessels
Angiography
Magnetic Resonance Spectroscopy
Thorax
Exercise
Skin

Keywords

  • Arteriovenous malformation
  • Endobronchial ultrasound
  • Osler-Weber-Rendu syndrome

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Pulmonary arteriovenous malformation of Osler-Weber-Rendu syndrome diagnosed by endobronchial ultrasound. / Kuo, Chih Hsi; Wang, Chun Hua; Kuo, Han Pin.

In: Respirology, Vol. 12, No. 2, 01.03.2007, p. 295-298.

Research output: Contribution to journalArticle

@article{efb5c263c2b848d8885fe3e9ce1356e8,
title = "Pulmonary arteriovenous malformation of Osler-Weber-Rendu syndrome diagnosed by endobronchial ultrasound",
abstract = "Osler-Weber-Rendu syndrome is a disease of hereditary telangiectasia with involvement of multiple visceral organs. Pulmonary arteriovenous malformation (AVM) is a frequent clinical manifestation, that may mimic pulmonary mass. In this report, endobronchial ultrasound (EBUS) was used in a 64-year-old woman with Osler-Weber-Rendu syndrome who had a solitary pulmonary mass associated with clinical evidence of a right-to-left shunt and was able to detect a pulsating hypoechoic mass connected to the right pulmonary artery suggesting of pulmonary AVM. Following magnetic resonance angiogram and chest CT as well as noting multiple telangiectasis on her skin and considering a strong family history, Osler-Weber-Rendu syndrome was confirmed. Exercise intolerance and desaturation improved after surgical resection of the pulmonary AVM. The echoic findings were correlated to the pathological features. EBUS can be used as a good diagnostic tool for determining the nature of peripheral lung lesions such as in this case, and EBUS may be of practical tool to investigate a lung mass when a vascular component is suspected.",
keywords = "Arteriovenous malformation, Endobronchial ultrasound, Osler-Weber-Rendu syndrome",
author = "Kuo, {Chih Hsi} and Wang, {Chun Hua} and Kuo, {Han Pin}",
year = "2007",
month = "3",
day = "1",
doi = "10.1111/j.1440-1843.2006.01025.x",
language = "English",
volume = "12",
pages = "295--298",
journal = "Respirology",
issn = "1323-7799",
publisher = "Wiley-Blackwell",
number = "2",

}

TY - JOUR

T1 - Pulmonary arteriovenous malformation of Osler-Weber-Rendu syndrome diagnosed by endobronchial ultrasound

AU - Kuo, Chih Hsi

AU - Wang, Chun Hua

AU - Kuo, Han Pin

PY - 2007/3/1

Y1 - 2007/3/1

N2 - Osler-Weber-Rendu syndrome is a disease of hereditary telangiectasia with involvement of multiple visceral organs. Pulmonary arteriovenous malformation (AVM) is a frequent clinical manifestation, that may mimic pulmonary mass. In this report, endobronchial ultrasound (EBUS) was used in a 64-year-old woman with Osler-Weber-Rendu syndrome who had a solitary pulmonary mass associated with clinical evidence of a right-to-left shunt and was able to detect a pulsating hypoechoic mass connected to the right pulmonary artery suggesting of pulmonary AVM. Following magnetic resonance angiogram and chest CT as well as noting multiple telangiectasis on her skin and considering a strong family history, Osler-Weber-Rendu syndrome was confirmed. Exercise intolerance and desaturation improved after surgical resection of the pulmonary AVM. The echoic findings were correlated to the pathological features. EBUS can be used as a good diagnostic tool for determining the nature of peripheral lung lesions such as in this case, and EBUS may be of practical tool to investigate a lung mass when a vascular component is suspected.

AB - Osler-Weber-Rendu syndrome is a disease of hereditary telangiectasia with involvement of multiple visceral organs. Pulmonary arteriovenous malformation (AVM) is a frequent clinical manifestation, that may mimic pulmonary mass. In this report, endobronchial ultrasound (EBUS) was used in a 64-year-old woman with Osler-Weber-Rendu syndrome who had a solitary pulmonary mass associated with clinical evidence of a right-to-left shunt and was able to detect a pulsating hypoechoic mass connected to the right pulmonary artery suggesting of pulmonary AVM. Following magnetic resonance angiogram and chest CT as well as noting multiple telangiectasis on her skin and considering a strong family history, Osler-Weber-Rendu syndrome was confirmed. Exercise intolerance and desaturation improved after surgical resection of the pulmonary AVM. The echoic findings were correlated to the pathological features. EBUS can be used as a good diagnostic tool for determining the nature of peripheral lung lesions such as in this case, and EBUS may be of practical tool to investigate a lung mass when a vascular component is suspected.

KW - Arteriovenous malformation

KW - Endobronchial ultrasound

KW - Osler-Weber-Rendu syndrome

UR - http://www.scopus.com/inward/record.url?scp=33846902786&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846902786&partnerID=8YFLogxK

U2 - 10.1111/j.1440-1843.2006.01025.x

DO - 10.1111/j.1440-1843.2006.01025.x

M3 - Article

VL - 12

SP - 295

EP - 298

JO - Respirology

JF - Respirology

SN - 1323-7799

IS - 2

ER -