Psychopathology and personality trait in subgroups of functional dyspepsia based on Rome III criteria

Yao Chun Hsu, Jyh Ming Liou, Shih Cheng Liao, Tzeng Huey Yang, Huei Tang Wu, Wei Lun Hsu, Hwai Jeng Lin, Hsiu Po Wang, Ming Shiang Wu

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

OBJECTIVES:Functional dyspepsia is a heterogeneous symptom complex that may be subdivided into postprandial distress syndrome and epigastric pain syndrome. We aimed to investigate differences among these subgroups in psychopathological factors and personality traits.METHODS:We enrolled 187 consecutive outpatients (72.2% female patients, mean age 42.6 years) with functional dyspepsia based on the Rome III criteria. Patients were interviewed and evaluated by the Brief Symptom Rating Scale and the short-form Maudsley personality inventory for severity of psychopathology and personality traits. Multiple linear regression models were built for each psychopathological dimension and personality trait to assess the independent association with each subclass diagnosis of functional dyspepsia.RESULTS:There was an overlap (n64, 34.2%) between the patients diagnosed with epigastric pain syndrome (n157, 84.0%) and those with postprandial distress syndrome (n94, 50.3%). Patients with symptoms compatible with both syndromes were psychopathologically more severe than either subgroup without overlapping. Multiple linear regression analysis demonstrated that the diagnosis of postprandial distress syndrome was independently associated with higher scores in overall psychopathological stress, and specifically in somatization (P0.034), depression (P0.028), phobia (P0.044), and additional symptoms (P0.001). However, epigastric pain syndrome was not associated with psychopathology. Postprandial distress was univariately associated with neuroticism, but the association was insignificant in the multivariate analysis (P0.136).CONCLUSIONS:The Rome III subgroups of functional dyspepsia significantly overlap. Patients fulfilling criteria for both subgroups had symptoms that were psychopathologically more severe than those of patients without overlapping. Diagnosis of postprandial distress syndrome, but not epigastric pain syndrome, is independently associated with psychopathological factors.

Original languageEnglish
Pages (from-to)2534-2542
Number of pages9
JournalAmerican Journal of Gastroenterology
Volume104
Issue number10
DOIs
Publication statusPublished - Oct 2009
Externally publishedYes

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Dyspepsia
Psychopathology
Personality
Pain
Linear Models
Personality Inventory
Phobic Disorders
Outpatients
Multivariate Analysis
Regression Analysis
Depression

ASJC Scopus subject areas

  • Gastroenterology
  • Medicine(all)

Cite this

Hsu, Y. C., Liou, J. M., Liao, S. C., Yang, T. H., Wu, H. T., Hsu, W. L., ... Wu, M. S. (2009). Psychopathology and personality trait in subgroups of functional dyspepsia based on Rome III criteria. American Journal of Gastroenterology, 104(10), 2534-2542. https://doi.org/10.1038/ajg.2009.328

Psychopathology and personality trait in subgroups of functional dyspepsia based on Rome III criteria. / Hsu, Yao Chun; Liou, Jyh Ming; Liao, Shih Cheng; Yang, Tzeng Huey; Wu, Huei Tang; Hsu, Wei Lun; Lin, Hwai Jeng; Wang, Hsiu Po; Wu, Ming Shiang.

In: American Journal of Gastroenterology, Vol. 104, No. 10, 10.2009, p. 2534-2542.

Research output: Contribution to journalArticle

Hsu, Yao Chun ; Liou, Jyh Ming ; Liao, Shih Cheng ; Yang, Tzeng Huey ; Wu, Huei Tang ; Hsu, Wei Lun ; Lin, Hwai Jeng ; Wang, Hsiu Po ; Wu, Ming Shiang. / Psychopathology and personality trait in subgroups of functional dyspepsia based on Rome III criteria. In: American Journal of Gastroenterology. 2009 ; Vol. 104, No. 10. pp. 2534-2542.
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abstract = "OBJECTIVES:Functional dyspepsia is a heterogeneous symptom complex that may be subdivided into postprandial distress syndrome and epigastric pain syndrome. We aimed to investigate differences among these subgroups in psychopathological factors and personality traits.METHODS:We enrolled 187 consecutive outpatients (72.2{\%} female patients, mean age 42.6 years) with functional dyspepsia based on the Rome III criteria. Patients were interviewed and evaluated by the Brief Symptom Rating Scale and the short-form Maudsley personality inventory for severity of psychopathology and personality traits. Multiple linear regression models were built for each psychopathological dimension and personality trait to assess the independent association with each subclass diagnosis of functional dyspepsia.RESULTS:There was an overlap (n64, 34.2{\%}) between the patients diagnosed with epigastric pain syndrome (n157, 84.0{\%}) and those with postprandial distress syndrome (n94, 50.3{\%}). Patients with symptoms compatible with both syndromes were psychopathologically more severe than either subgroup without overlapping. Multiple linear regression analysis demonstrated that the diagnosis of postprandial distress syndrome was independently associated with higher scores in overall psychopathological stress, and specifically in somatization (P0.034), depression (P0.028), phobia (P0.044), and additional symptoms (P0.001). However, epigastric pain syndrome was not associated with psychopathology. Postprandial distress was univariately associated with neuroticism, but the association was insignificant in the multivariate analysis (P0.136).CONCLUSIONS:The Rome III subgroups of functional dyspepsia significantly overlap. Patients fulfilling criteria for both subgroups had symptoms that were psychopathologically more severe than those of patients without overlapping. Diagnosis of postprandial distress syndrome, but not epigastric pain syndrome, is independently associated with psychopathological factors.",
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T1 - Psychopathology and personality trait in subgroups of functional dyspepsia based on Rome III criteria

AU - Hsu, Yao Chun

AU - Liou, Jyh Ming

AU - Liao, Shih Cheng

AU - Yang, Tzeng Huey

AU - Wu, Huei Tang

AU - Hsu, Wei Lun

AU - Lin, Hwai Jeng

AU - Wang, Hsiu Po

AU - Wu, Ming Shiang

PY - 2009/10

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N2 - OBJECTIVES:Functional dyspepsia is a heterogeneous symptom complex that may be subdivided into postprandial distress syndrome and epigastric pain syndrome. We aimed to investigate differences among these subgroups in psychopathological factors and personality traits.METHODS:We enrolled 187 consecutive outpatients (72.2% female patients, mean age 42.6 years) with functional dyspepsia based on the Rome III criteria. Patients were interviewed and evaluated by the Brief Symptom Rating Scale and the short-form Maudsley personality inventory for severity of psychopathology and personality traits. Multiple linear regression models were built for each psychopathological dimension and personality trait to assess the independent association with each subclass diagnosis of functional dyspepsia.RESULTS:There was an overlap (n64, 34.2%) between the patients diagnosed with epigastric pain syndrome (n157, 84.0%) and those with postprandial distress syndrome (n94, 50.3%). Patients with symptoms compatible with both syndromes were psychopathologically more severe than either subgroup without overlapping. Multiple linear regression analysis demonstrated that the diagnosis of postprandial distress syndrome was independently associated with higher scores in overall psychopathological stress, and specifically in somatization (P0.034), depression (P0.028), phobia (P0.044), and additional symptoms (P0.001). However, epigastric pain syndrome was not associated with psychopathology. Postprandial distress was univariately associated with neuroticism, but the association was insignificant in the multivariate analysis (P0.136).CONCLUSIONS:The Rome III subgroups of functional dyspepsia significantly overlap. Patients fulfilling criteria for both subgroups had symptoms that were psychopathologically more severe than those of patients without overlapping. Diagnosis of postprandial distress syndrome, but not epigastric pain syndrome, is independently associated with psychopathological factors.

AB - OBJECTIVES:Functional dyspepsia is a heterogeneous symptom complex that may be subdivided into postprandial distress syndrome and epigastric pain syndrome. We aimed to investigate differences among these subgroups in psychopathological factors and personality traits.METHODS:We enrolled 187 consecutive outpatients (72.2% female patients, mean age 42.6 years) with functional dyspepsia based on the Rome III criteria. Patients were interviewed and evaluated by the Brief Symptom Rating Scale and the short-form Maudsley personality inventory for severity of psychopathology and personality traits. Multiple linear regression models were built for each psychopathological dimension and personality trait to assess the independent association with each subclass diagnosis of functional dyspepsia.RESULTS:There was an overlap (n64, 34.2%) between the patients diagnosed with epigastric pain syndrome (n157, 84.0%) and those with postprandial distress syndrome (n94, 50.3%). Patients with symptoms compatible with both syndromes were psychopathologically more severe than either subgroup without overlapping. Multiple linear regression analysis demonstrated that the diagnosis of postprandial distress syndrome was independently associated with higher scores in overall psychopathological stress, and specifically in somatization (P0.034), depression (P0.028), phobia (P0.044), and additional symptoms (P0.001). However, epigastric pain syndrome was not associated with psychopathology. Postprandial distress was univariately associated with neuroticism, but the association was insignificant in the multivariate analysis (P0.136).CONCLUSIONS:The Rome III subgroups of functional dyspepsia significantly overlap. Patients fulfilling criteria for both subgroups had symptoms that were psychopathologically more severe than those of patients without overlapping. Diagnosis of postprandial distress syndrome, but not epigastric pain syndrome, is independently associated with psychopathological factors.

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