Protein-protein interaction prediction based on association rules of protein functional regions

Hung Fei, Chiu Hung-Wen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In cells, protein-protein interaction (PPI) controls the biological process. For decoding mechanism of diseases, investigators attempt to predict PPI. Recently PPI is a popular subject in bioinformatics. Functional regions of compact protein structure interact with others. Nearly a lot of PPI-related tools were produced and available. Furthermore, researchers applied computational methods with statistic methods to predict PPIs. In some researches, the investigators had tried to use it to find out the relationship of protein pair in PPI. In this paper, we collected proteins and PPI data from DIP and IntAct. Next, the data of functional regions was downloaded from UNIPROT. They were integrated into our database. Moreover, two modules of PPI prediction were established with Saccharomyces cerevisiae (yeast) and Drosophila melanogaster (fruit fly) by an association rule tool. We applied two different species' PPIs for evidence of the two modules.

Original languageEnglish
Title of host publicationSecond International Conference on Innovative Computing, Information and Control, ICICIC 2007
DOIs
Publication statusPublished - 2008
Event2nd International Conference on Innovative Computing, Information and Control, ICICIC 2007 - Kumamoto, Japan
Duration: Sep 5 2007Sep 7 2007

Other

Other2nd International Conference on Innovative Computing, Information and Control, ICICIC 2007
CountryJapan
CityKumamoto
Period9/5/079/7/07

ASJC Scopus subject areas

  • Computer Science(all)
  • Mechanical Engineering

Fingerprint Dive into the research topics of 'Protein-protein interaction prediction based on association rules of protein functional regions'. Together they form a unique fingerprint.

  • Cite this

    Fei, H., & Hung-Wen, C. (2008). Protein-protein interaction prediction based on association rules of protein functional regions. In Second International Conference on Innovative Computing, Information and Control, ICICIC 2007 [4428001] https://doi.org/10.1109/ICICIC.2007.466