Protective effects of trilinolein extracted from Panax notoginseng against cardiovascular disease

Paul Chan, G. Neil Thomas, Brian Tomlinson

Research output: Contribution to journalArticle

81 Citations (Scopus)

Abstract

Trilinolein is a triacylglycerol purified from a commonly used traditional Chinese medicine Panax notoginseng. Trilinolein has been reported to provide a number of beneficial effects including reducing thrombogenicity and arrhythmias and increasing erythrocyte deformability. Additionally, trilinolein has been reported to be an antioxidant, which can counteract free radical damage associated with atherogenesis, and myocardial damage seen with ischaemia and reperfusion. These pharmacologic effects may explain the perceived benefits derived from treating circulatory disorders with the herb over the centuries.

Original languageEnglish
Pages (from-to)1157-1162
Number of pages6
JournalActa Pharmacologica Sinica
Volume23
Issue number12
Publication statusPublished - Dec 1 2002

Fingerprint

Panax notoginseng
Cardiovascular Diseases
Erythrocyte Deformability
Chinese Traditional Medicine
Formability
Medicine
Reperfusion
Free Radicals
Cardiac Arrhythmias
Atherosclerosis
Triglycerides
Ischemia
Antioxidants
trilinolein

Keywords

  • Antioxidants
  • Cardiovascular system
  • Chinese traditional medicine
  • Panax notoginseng
  • Trilinolein

ASJC Scopus subject areas

  • Chemistry(all)
  • Pharmacology

Cite this

Protective effects of trilinolein extracted from Panax notoginseng against cardiovascular disease. / Chan, Paul; Thomas, G. Neil; Tomlinson, Brian.

In: Acta Pharmacologica Sinica, Vol. 23, No. 12, 01.12.2002, p. 1157-1162.

Research output: Contribution to journalArticle

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