Prostatic relaxation induced by loperamide is reduced in spontaneously hypertensive rats

Liang Ming Lee, Chih Cheng Lu, Hsien Hui Chung, Juei Tang Cheng

Research output: Contribution to journalArticle

Abstract

This paper shows a new finding about the decrease of relaxative response to loperamide in prostate of spontaneously hypertensive rats (SHR) as compare to normal rats (WKY). Authors demonstrated the reduction of ATP-sensitive potassium channels is resposible for this change using immunoblotting analysis and the decrease of action induced by diazoxide. This view is not mentioned before and is the first one reporting this result.

Original languageEnglish
Article number941685
JournalScientific World Journal
Volume2012
DOIs
Publication statusPublished - 2012

Fingerprint

Loperamide
Diazoxide
KATP Channels
Inbred WKY Rats
Inbred SHR Rats
Immunoblotting
Rats
Prostate
potassium
analysis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)
  • Medicine(all)

Cite this

Prostatic relaxation induced by loperamide is reduced in spontaneously hypertensive rats. / Lee, Liang Ming; Lu, Chih Cheng; Chung, Hsien Hui; Cheng, Juei Tang.

In: Scientific World Journal, Vol. 2012, 941685, 2012.

Research output: Contribution to journalArticle

Lee, Liang Ming ; Lu, Chih Cheng ; Chung, Hsien Hui ; Cheng, Juei Tang. / Prostatic relaxation induced by loperamide is reduced in spontaneously hypertensive rats. In: Scientific World Journal. 2012 ; Vol. 2012.
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