Prostatic Pure Small Cell Carcinoma v.s. Mixed-Type Small Cell Carcinoma

Analysis of Two Cases

Chih-Kai Hsu, Chien-Jui Cheng, Kuan-Chou Chen, Han-Sun Chiang, Jan-Show Chu

Research output: Contribution to journalArticle

Abstract

We analyzed 2 cases of small cell carcinoma of the prostate. One patient had pure small cell carcinoma with multiple organ metastasis, while the other had a mixed-type carcinoma. The immunohistochemical studies revealed positive reactions to chromogranin A, synaptophysin, and cytokeratin stains, and negative for PSA stain over both small cell carcinoma foci. These 2 patients were immediately treated, and partial resolution of the previous metastatic bone lesions was noted after receiving 5 courses of chemotherapy with the combination of gemcitabine, carboplatin, and irradiation therapy in case 1, while adjuvant irradiation was scheduled for case 2.
Original languageEnglish
Pages (from-to)115-119
Number of pages5
Journal臺灣泌尿科醫學會雜誌
Volume16
Issue number3
Publication statusPublished - 2005

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Small Cell Carcinoma
gemcitabine
Coloring Agents
Chromogranin A
Synaptophysin
Carboplatin
Keratins
Combination Drug Therapy
Prostate
Neoplasm Metastasis
Carcinoma
Bone and Bones
Therapeutics

Keywords

  • 攝護腺
  • 小細胞癌
  • 神經內分泌
  • 組織免疫染色
  • prostate
  • small cell carcinoma
  • neuroendocrine
  • immunohistochemical studies

Cite this

Prostatic Pure Small Cell Carcinoma v.s. Mixed-Type Small Cell Carcinoma : Analysis of Two Cases. / Hsu, Chih-Kai; Cheng, Chien-Jui; Chen, Kuan-Chou; Chiang, Han-Sun; Chu, Jan-Show.

In: 臺灣泌尿科醫學會雜誌, Vol. 16, No. 3, 2005, p. 115-119.

Research output: Contribution to journalArticle

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AU - Chiang, Han-Sun

AU - Chu, Jan-Show

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N2 - We analyzed 2 cases of small cell carcinoma of the prostate. One patient had pure small cell carcinoma with multiple organ metastasis, while the other had a mixed-type carcinoma. The immunohistochemical studies revealed positive reactions to chromogranin A, synaptophysin, and cytokeratin stains, and negative for PSA stain over both small cell carcinoma foci. These 2 patients were immediately treated, and partial resolution of the previous metastatic bone lesions was noted after receiving 5 courses of chemotherapy with the combination of gemcitabine, carboplatin, and irradiation therapy in case 1, while adjuvant irradiation was scheduled for case 2.

AB - We analyzed 2 cases of small cell carcinoma of the prostate. One patient had pure small cell carcinoma with multiple organ metastasis, while the other had a mixed-type carcinoma. The immunohistochemical studies revealed positive reactions to chromogranin A, synaptophysin, and cytokeratin stains, and negative for PSA stain over both small cell carcinoma foci. These 2 patients were immediately treated, and partial resolution of the previous metastatic bone lesions was noted after receiving 5 courses of chemotherapy with the combination of gemcitabine, carboplatin, and irradiation therapy in case 1, while adjuvant irradiation was scheduled for case 2.

KW - 攝護腺

KW - 小細胞癌

KW - 神經內分泌

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