Prospective Observational Study on acute Appendicitis Worldwide (POSAW)

Massimo Sartelli; Gian L. Baiocchi; Salomone Di Saverio; Francesco Ferrara; Francesco M. Labricciosa; Luca Ansaloni; Federico Coccolini; Deepak Vijayan; Ashraf Abbas; Hariscine K. Abongwa; John Agboola; Adamu Ahmed; Lali Akhmeteli; Nezih Akkapulu; Seckin Akkucuk; Fatih Altintoprak; Aurelia L. Andreiev; Dimitrios Anyfantakis; Boiko Atanasov; Miklosh Bala; Dimitrios Balalis; Oussama Baraket; Giovanni Bellanova; Marcelo Beltran; Renato Bessa Melo; Roberto Bini; Konstantinos Bouliaris; Daniele Brunelli; Adrian Castillo; Marco Catani; Asri Che Jusoh; Alain Chichom-Mefire; Gianfranco Cocorullo; Raul Coimbra; Elif Colak; Silvia Costa; Koray Das; Samir Delibegovic; Zaza Demetrashvili; Isidoro Di Carlo; Nadezda Kiseleva; Tamer El Zalabany; Mario Faro; Margarida Ferreira; Gustavo P. Fraga; Mahir Gachabayov; Wagih M. Ghnnam; Teresa Giménez Maurel; Georgios Gkiokas; Carlos A. Gomes; Ewen Griffiths; Ali Guner; Sanjay Gupta; Andreas Hecker; Elcio S. Hirano; Adrien Hodonou; Martin Hutan; Orestis Ioannidis; Arda Isik; Georgy Ivakhov; Sumita Jain; Mantas Jokubauskas; Aleksandar Karamarkovic; Saila Kauhanen; Robin Kaushik; Alfie Kavalakat; Jakub Kenig; Vladimir Khokha; Desmond Khor; Dennis Kim; Jae I. Kim; Victor Kong; Konstantinos Lasithiotakis; Pedro Leão; Miguel Leon; Andrey Litvin; Varut Lohsiriwat; Eudaldo López-Tomassetti Fernandez; Eftychios Lostoridis; James Maciel; Piotr Major; Ana Dimova; Dimitrios Manatakis; Athanasio Marinis; Aleix Martinez-Perez; Sanjay Marwah; Michael McFarlane; Cristian Mesina; Michał Pȩdziwiatr; Nickos Michalopoulos; Evangelos Misiakos; Ali Mohamedahmed; Radu Moldovanu; Giulia Montori; Raghuveer Mysore Narayana; Ionut Negoi; Ioannis Nikolopoulos; Giuseppe Novelli; Viktors Novikovs; Iyiade Olaoye; Abdelkarim Omari; Carlos A. Ordoñez; Mouaqit Ouadii; Zeynep Ozkan; Ajay Pal; Gian M. Palini; Lars I. Partecke; Francesco Pata; Michał Pȩdziwiatr; Gerson A. Pereira Júnior; Tadeja Pintar; Magdalena Pisarska; Cesar F. Ploneda-Valencia; Konstantinos Pouggouras; Vinod Prabhu; Padmakumar Ramakrishnapillai; Jean Marc Regimbeau; Marianne Reitz; Daniel Rios-Cruz; Sten Saar; Boris Sakakushev; Charalampos Seretis; Alexander Sazhin; Vishal Shelat; Matej Skrovina; Dmitry Smirnov; Charalampos Spyropoulos; Marcin Strzałka; Peep Talving; Ricardo A. Teixeira Gonsaga; George Theobald; Gia Tomadze; Myftar Torba; Cristian Tranà; Jan Ulrych; Mustafa Y. Uzunoğlu; Alin Vasilescu; Savino Occhionorelli; Aurélien Venara; Andras Vereczkei; Nereo Vettoretto; Nutu Vlad; Maciej Walȩdziak; Tonguç U. Yilmaz; Kuo Ching Yuan; Cui Yunfeng; Justas Zilinskas; Gérard Grelpois; Fausto Catena

doi:10.1186/s13017-018-0179-0

Prospective Observational Study on acute Appendicitis Worldwide (POSAW)

Massimo Sartelli, Gian L. Baiocchi, Salomone Di Saverio, Francesco Ferrara, Francesco M. Labricciosa, Luca Ansaloni, Federico Coccolini, Deepak Vijayan, Ashraf Abbas, Hariscine K. Abongwa, John Agboola, Adamu Ahmed, Lali Akhmeteli, Nezih Akkapulu, Seckin Akkucuk, Fatih Altintoprak, Aurelia L. Andreiev, Dimitrios Anyfantakis, Boiko Atanasov, Miklosh BalaDimitrios Balalis, Oussama Baraket, Giovanni Bellanova, Marcelo Beltran, Renato Bessa Melo, Roberto Bini, Konstantinos Bouliaris, Daniele Brunelli, Adrian Castillo, Marco Catani, Asri Che Jusoh, Alain Chichom-Mefire, Gianfranco Cocorullo, Raul Coimbra, Elif Colak, Silvia Costa, Koray Das, Samir Delibegovic, Zaza Demetrashvili, Isidoro Di Carlo, Nadezda Kiseleva, Tamer El Zalabany, Mario Faro, Margarida Ferreira, Gustavo P. Fraga, Mahir Gachabayov, Wagih M. Ghnnam, Teresa Giménez Maurel, Georgios Gkiokas, Carlos A. Gomes, Ewen Griffiths, Ali Guner, Sanjay Gupta, Andreas Hecker, Elcio S. Hirano, Adrien Hodonou, Martin Hutan, Orestis Ioannidis, Arda Isik, Georgy Ivakhov, Sumita Jain, Mantas Jokubauskas, Aleksandar Karamarkovic, Saila Kauhanen, Robin Kaushik, Alfie Kavalakat, Jakub Kenig, Vladimir Khokha, Desmond Khor, Dennis Kim, Jae I. Kim, Victor Kong, Konstantinos Lasithiotakis, Pedro Leão, Miguel Leon, Andrey Litvin, Varut Lohsiriwat, Eudaldo López-Tomassetti Fernandez, Eftychios Lostoridis, James Maciel, Piotr Major, Ana Dimova, Dimitrios Manatakis, Athanasio Marinis, Aleix Martinez-Perez, Sanjay Marwah, Michael McFarlane, Cristian Mesina, Michał Pȩdziwiatr, Nickos Michalopoulos, Evangelos Misiakos, Ali Mohamedahmed, Radu Moldovanu, Giulia Montori, Raghuveer Mysore Narayana, Ionut Negoi, Ioannis Nikolopoulos, Giuseppe Novelli, Viktors Novikovs, Iyiade Olaoye, Abdelkarim Omari, Carlos A. Ordoñez, Mouaqit Ouadii, Zeynep Ozkan, Ajay Pal, Gian M. Palini, Lars I. Partecke, Francesco Pata, Michał Pȩdziwiatr, Gerson A. Pereira Júnior, Tadeja Pintar, Magdalena Pisarska, Cesar F. Ploneda-Valencia, Konstantinos Pouggouras, Vinod Prabhu, Padmakumar Ramakrishnapillai, Jean Marc Regimbeau, Marianne Reitz, Daniel Rios-Cruz, Sten Saar, Boris Sakakushev, Charalampos Seretis, Alexander Sazhin, Vishal Shelat, Matej Skrovina, Dmitry Smirnov, Charalampos Spyropoulos, Marcin Strzałka, Peep Talving, Ricardo A. Teixeira Gonsaga, George Theobald, Gia Tomadze, Myftar Torba, Cristian Tranà, Jan Ulrych, Mustafa Y. Uzunoğlu, Alin Vasilescu, Savino Occhionorelli, Aurélien Venara, Andras Vereczkei, Nereo Vettoretto, Nutu Vlad, Maciej Walȩdziak, Tonguç U. Yilmaz, Kuo Ching Yuan, Cui Yunfeng, Justas Zilinskas, Gérard Grelpois, Fausto Catena

Research output: Contribution to journal › Article

38 Citations (Scopus)

Abstract

Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments. Methods: This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016-September 30, 2016). All consecutive patients admitted to surgical departments with a clinical diagnosis of AA were included in the study. Results: A total of 4282 patients were enrolled in the POSAW study, 1928 (45%) women and 2354 (55%) men, with a median age of 29 years. Nine hundred and seven (21.2%) patients underwent an abdominal CT scan, 1856 (43.3%) patients an US, and 285 (6.7%) patients both CT scan and US. A total of 4097 (95.7%) patients underwent surgery; 1809 (42.2%) underwent open appendectomy and 2215 (51.7%) had laparoscopic appendectomy. One hundred eighty-five (4.3%) patients were managed conservatively. Major complications occurred in 199 patients (4.6%). The overall mortality rate was 0.28%. Conclusions: The results of the present study confirm the clinical value of imaging techniques and prognostic scores. Appendectomy remains the most effective treatment of acute appendicitis. Mortality rate is low.

Original language	English
Article number	19
Journal	World Journal of Emergency Surgery
Volume	13
Issue number	1
DOIs	https://doi.org/10.1186/s13017-018-0179-0
Publication status	Published - Apr 16 2018
Externally published	Yes

Keywords

Acute appendicitis
Antibiotics
Diagnosis
Management
Surgery

ASJC Scopus subject areas

Surgery
Emergency Medicine

Access to Document

10.1186/s13017-018-0179-0

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Sartelli, M., Baiocchi, G. L., Di Saverio, S., Ferrara, F., Labricciosa, F. M., Ansaloni, L., Coccolini, F., Vijayan, D., Abbas, A., Abongwa, H. K., Agboola, J., Ahmed, A., Akhmeteli, L., Akkapulu, N., Akkucuk, S., Altintoprak, F., Andreiev, A. L., Anyfantakis, D., Atanasov, B., ... Catena, F. (2018). Prospective Observational Study on acute Appendicitis Worldwide (POSAW). World Journal of Emergency Surgery, 13(1), [19]. https://doi.org/10.1186/s13017-018-0179-0

Prospective Observational Study on acute Appendicitis Worldwide (POSAW). / Sartelli, Massimo; Baiocchi, Gian L.; Di Saverio, Salomone; Ferrara, Francesco; Labricciosa, Francesco M.; Ansaloni, Luca; Coccolini, Federico; Vijayan, Deepak; Abbas, Ashraf; Abongwa, Hariscine K.; Agboola, John; Ahmed, Adamu; Akhmeteli, Lali; Akkapulu, Nezih; Akkucuk, Seckin; Altintoprak, Fatih; Andreiev, Aurelia L.; Anyfantakis, Dimitrios; Atanasov, Boiko; Bala, Miklosh; Balalis, Dimitrios; Baraket, Oussama; Bellanova, Giovanni; Beltran, Marcelo; Melo, Renato Bessa; Bini, Roberto; Bouliaris, Konstantinos; Brunelli, Daniele; Castillo, Adrian; Catani, Marco; Che Jusoh, Asri; Chichom-Mefire, Alain; Cocorullo, Gianfranco; Coimbra, Raul; Colak, Elif; Costa, Silvia; Das, Koray; Delibegovic, Samir; Demetrashvili, Zaza; Di Carlo, Isidoro; Kiseleva, Nadezda; El Zalabany, Tamer; Faro, Mario; Ferreira, Margarida; Fraga, Gustavo P.; Gachabayov, Mahir; Ghnnam, Wagih M.; Giménez Maurel, Teresa; Gkiokas, Georgios; Gomes, Carlos A.; Griffiths, Ewen; Guner, Ali; Gupta, Sanjay; Hecker, Andreas; Hirano, Elcio S.; Hodonou, Adrien; Hutan, Martin; Ioannidis, Orestis; Isik, Arda; Ivakhov, Georgy; Jain, Sumita; Jokubauskas, Mantas; Karamarkovic, Aleksandar; Kauhanen, Saila; Kaushik, Robin; Kavalakat, Alfie; Kenig, Jakub; Khokha, Vladimir; Khor, Desmond; Kim, Dennis; Kim, Jae I.; Kong, Victor; Lasithiotakis, Konstantinos; Leão, Pedro; Leon, Miguel; Litvin, Andrey; Lohsiriwat, Varut; López-Tomassetti Fernandez, Eudaldo; Lostoridis, Eftychios; Maciel, James; Major, Piotr; Dimova, Ana; Manatakis, Dimitrios; Marinis, Athanasio; Martinez-Perez, Aleix; Marwah, Sanjay; McFarlane, Michael; Mesina, Cristian; Pȩdziwiatr, Michał; Michalopoulos, Nickos; Misiakos, Evangelos; Mohamedahmed, Ali; Moldovanu, Radu; Montori, Giulia; Mysore Narayana, Raghuveer; Negoi, Ionut; Nikolopoulos, Ioannis; Novelli, Giuseppe; Novikovs, Viktors; Olaoye, Iyiade; Omari, Abdelkarim; Ordoñez, Carlos A.; Ouadii, Mouaqit; Ozkan, Zeynep; Pal, Ajay; Palini, Gian M.; Partecke, Lars I.; Pata, Francesco; Pȩdziwiatr, Michał; Pereira Júnior, Gerson A.; Pintar, Tadeja; Pisarska, Magdalena; Ploneda-Valencia, Cesar F.; Pouggouras, Konstantinos; Prabhu, Vinod; Ramakrishnapillai, Padmakumar; Regimbeau, Jean Marc; Reitz, Marianne; Rios-Cruz, Daniel; Saar, Sten; Sakakushev, Boris; Seretis, Charalampos; Sazhin, Alexander; Shelat, Vishal; Skrovina, Matej; Smirnov, Dmitry; Spyropoulos, Charalampos; Strzałka, Marcin; Talving, Peep; Teixeira Gonsaga, Ricardo A.; Theobald, George; Tomadze, Gia; Torba, Myftar; Tranà, Cristian; Ulrych, Jan; Uzunoğlu, Mustafa Y.; Vasilescu, Alin; Occhionorelli, Savino; Venara, Aurélien; Vereczkei, Andras; Vettoretto, Nereo; Vlad, Nutu; Walȩdziak, Maciej; Yilmaz, Tonguç U.; Yuan, Kuo Ching; Yunfeng, Cui; Zilinskas, Justas; Grelpois, Gérard; Catena, Fausto.

In: World Journal of Emergency Surgery, Vol. 13, No. 1, 19, 16.04.2018.

Research output: Contribution to journal › Article

Sartelli, M, Baiocchi, GL, Di Saverio, S, Ferrara, F, Labricciosa, FM, Ansaloni, L, Coccolini, F, Vijayan, D, Abbas, A, Abongwa, HK, Agboola, J, Ahmed, A, Akhmeteli, L, Akkapulu, N, Akkucuk, S, Altintoprak, F, Andreiev, AL, Anyfantakis, D, Atanasov, B, Bala, M, Balalis, D, Baraket, O, Bellanova, G, Beltran, M, Melo, RB, Bini, R, Bouliaris, K, Brunelli, D, Castillo, A, Catani, M, Che Jusoh, A, Chichom-Mefire, A, Cocorullo, G, Coimbra, R, Colak, E, Costa, S, Das, K, Delibegovic, S, Demetrashvili, Z, Di Carlo, I, Kiseleva, N, El Zalabany, T, Faro, M, Ferreira, M, Fraga, GP, Gachabayov, M, Ghnnam, WM, Giménez Maurel, T, Gkiokas, G, Gomes, CA, Griffiths, E, Guner, A, Gupta, S, Hecker, A, Hirano, ES, Hodonou, A, Hutan, M, Ioannidis, O, Isik, A, Ivakhov, G, Jain, S, Jokubauskas, M, Karamarkovic, A, Kauhanen, S, Kaushik, R, Kavalakat, A, Kenig, J, Khokha, V, Khor, D, Kim, D, Kim, JI, Kong, V, Lasithiotakis, K, Leão, P, Leon, M, Litvin, A, Lohsiriwat, V, López-Tomassetti Fernandez, E, Lostoridis, E, Maciel, J, Major, P, Dimova, A, Manatakis, D, Marinis, A, Martinez-Perez, A, Marwah, S, McFarlane, M, Mesina, C, Pȩdziwiatr, M, Michalopoulos, N, Misiakos, E, Mohamedahmed, A, Moldovanu, R, Montori, G, Mysore Narayana, R, Negoi, I, Nikolopoulos, I, Novelli, G, Novikovs, V, Olaoye, I, Omari, A, Ordoñez, CA, Ouadii, M, Ozkan, Z, Pal, A, Palini, GM, Partecke, LI, Pata, F, Pȩdziwiatr, M, Pereira Júnior, GA, Pintar, T, Pisarska, M, Ploneda-Valencia, CF, Pouggouras, K, Prabhu, V, Ramakrishnapillai, P, Regimbeau, JM, Reitz, M, Rios-Cruz, D, Saar, S, Sakakushev, B, Seretis, C, Sazhin, A, Shelat, V, Skrovina, M, Smirnov, D, Spyropoulos, C, Strzałka, M, Talving, P, Teixeira Gonsaga, RA, Theobald, G, Tomadze, G, Torba, M, Tranà, C, Ulrych, J, Uzunoğlu, MY, Vasilescu, A, Occhionorelli, S, Venara, A, Vereczkei, A, Vettoretto, N, Vlad, N, Walȩdziak, M, Yilmaz, TU, Yuan, KC, Yunfeng, C, Zilinskas, J, Grelpois, G & Catena, F 2018, 'Prospective Observational Study on acute Appendicitis Worldwide (POSAW)', World Journal of Emergency Surgery, vol. 13, no. 1, 19. https://doi.org/10.1186/s13017-018-0179-0

Sartelli, Massimo ; Baiocchi, Gian L. ; Di Saverio, Salomone ; Ferrara, Francesco ; Labricciosa, Francesco M. ; Ansaloni, Luca ; Coccolini, Federico ; Vijayan, Deepak ; Abbas, Ashraf ; Abongwa, Hariscine K. ; Agboola, John ; Ahmed, Adamu ; Akhmeteli, Lali ; Akkapulu, Nezih ; Akkucuk, Seckin ; Altintoprak, Fatih ; Andreiev, Aurelia L. ; Anyfantakis, Dimitrios ; Atanasov, Boiko ; Bala, Miklosh ; Balalis, Dimitrios ; Baraket, Oussama ; Bellanova, Giovanni ; Beltran, Marcelo ; Melo, Renato Bessa ; Bini, Roberto ; Bouliaris, Konstantinos ; Brunelli, Daniele ; Castillo, Adrian ; Catani, Marco ; Che Jusoh, Asri ; Chichom-Mefire, Alain ; Cocorullo, Gianfranco ; Coimbra, Raul ; Colak, Elif ; Costa, Silvia ; Das, Koray ; Delibegovic, Samir ; Demetrashvili, Zaza ; Di Carlo, Isidoro ; Kiseleva, Nadezda ; El Zalabany, Tamer ; Faro, Mario ; Ferreira, Margarida ; Fraga, Gustavo P. ; Gachabayov, Mahir ; Ghnnam, Wagih M. ; Giménez Maurel, Teresa ; Gkiokas, Georgios ; Gomes, Carlos A. ; Griffiths, Ewen ; Guner, Ali ; Gupta, Sanjay ; Hecker, Andreas ; Hirano, Elcio S. ; Hodonou, Adrien ; Hutan, Martin ; Ioannidis, Orestis ; Isik, Arda ; Ivakhov, Georgy ; Jain, Sumita ; Jokubauskas, Mantas ; Karamarkovic, Aleksandar ; Kauhanen, Saila ; Kaushik, Robin ; Kavalakat, Alfie ; Kenig, Jakub ; Khokha, Vladimir ; Khor, Desmond ; Kim, Dennis ; Kim, Jae I. ; Kong, Victor ; Lasithiotakis, Konstantinos ; Leão, Pedro ; Leon, Miguel ; Litvin, Andrey ; Lohsiriwat, Varut ; López-Tomassetti Fernandez, Eudaldo ; Lostoridis, Eftychios ; Maciel, James ; Major, Piotr ; Dimova, Ana ; Manatakis, Dimitrios ; Marinis, Athanasio ; Martinez-Perez, Aleix ; Marwah, Sanjay ; McFarlane, Michael ; Mesina, Cristian ; Pȩdziwiatr, Michał ; Michalopoulos, Nickos ; Misiakos, Evangelos ; Mohamedahmed, Ali ; Moldovanu, Radu ; Montori, Giulia ; Mysore Narayana, Raghuveer ; Negoi, Ionut ; Nikolopoulos, Ioannis ; Novelli, Giuseppe ; Novikovs, Viktors ; Olaoye, Iyiade ; Omari, Abdelkarim ; Ordoñez, Carlos A. ; Ouadii, Mouaqit ; Ozkan, Zeynep ; Pal, Ajay ; Palini, Gian M. ; Partecke, Lars I. ; Pata, Francesco ; Pȩdziwiatr, Michał ; Pereira Júnior, Gerson A. ; Pintar, Tadeja ; Pisarska, Magdalena ; Ploneda-Valencia, Cesar F. ; Pouggouras, Konstantinos ; Prabhu, Vinod ; Ramakrishnapillai, Padmakumar ; Regimbeau, Jean Marc ; Reitz, Marianne ; Rios-Cruz, Daniel ; Saar, Sten ; Sakakushev, Boris ; Seretis, Charalampos ; Sazhin, Alexander ; Shelat, Vishal ; Skrovina, Matej ; Smirnov, Dmitry ; Spyropoulos, Charalampos ; Strzałka, Marcin ; Talving, Peep ; Teixeira Gonsaga, Ricardo A. ; Theobald, George ; Tomadze, Gia ; Torba, Myftar ; Tranà, Cristian ; Ulrych, Jan ; Uzunoğlu, Mustafa Y. ; Vasilescu, Alin ; Occhionorelli, Savino ; Venara, Aurélien ; Vereczkei, Andras ; Vettoretto, Nereo ; Vlad, Nutu ; Walȩdziak, Maciej ; Yilmaz, Tonguç U. ; Yuan, Kuo Ching ; Yunfeng, Cui ; Zilinskas, Justas ; Grelpois, Gérard ; Catena, Fausto. / Prospective Observational Study on acute Appendicitis Worldwide (POSAW). In: World Journal of Emergency Surgery. 2018 ; Vol. 13, No. 1.

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title = "Prospective Observational Study on acute Appendicitis Worldwide (POSAW)",

abstract = "Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments. Methods: This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016-September 30, 2016). All consecutive patients admitted to surgical departments with a clinical diagnosis of AA were included in the study. Results: A total of 4282 patients were enrolled in the POSAW study, 1928 (45%) women and 2354 (55%) men, with a median age of 29 years. Nine hundred and seven (21.2%) patients underwent an abdominal CT scan, 1856 (43.3%) patients an US, and 285 (6.7%) patients both CT scan and US. A total of 4097 (95.7%) patients underwent surgery; 1809 (42.2%) underwent open appendectomy and 2215 (51.7%) had laparoscopic appendectomy. One hundred eighty-five (4.3%) patients were managed conservatively. Major complications occurred in 199 patients (4.6%). The overall mortality rate was 0.28%. Conclusions: The results of the present study confirm the clinical value of imaging techniques and prognostic scores. Appendectomy remains the most effective treatment of acute appendicitis. Mortality rate is low.",

keywords = "Acute appendicitis, Antibiotics, Diagnosis, Management, Surgery",

author = "Massimo Sartelli and Baiocchi, {Gian L.} and {Di Saverio}, Salomone and Francesco Ferrara and Labricciosa, {Francesco M.} and Luca Ansaloni and Federico Coccolini and Deepak Vijayan and Ashraf Abbas and Abongwa, {Hariscine K.} and John Agboola and Adamu Ahmed and Lali Akhmeteli and Nezih Akkapulu and Seckin Akkucuk and Fatih Altintoprak and Andreiev, {Aurelia L.} and Dimitrios Anyfantakis and Boiko Atanasov and Miklosh Bala and Dimitrios Balalis and Oussama Baraket and Giovanni Bellanova and Marcelo Beltran and Melo, {Renato Bessa} and Roberto Bini and Konstantinos Bouliaris and Daniele Brunelli and Adrian Castillo and Marco Catani and {Che Jusoh}, Asri and Alain Chichom-Mefire and Gianfranco Cocorullo and Raul Coimbra and Elif Colak and Silvia Costa and Koray Das and Samir Delibegovic and Zaza Demetrashvili and {Di Carlo}, Isidoro and Nadezda Kiseleva and {El Zalabany}, Tamer and Mario Faro and Margarida Ferreira and Fraga, {Gustavo P.} and Mahir Gachabayov and Ghnnam, {Wagih M.} and {Gim{\'e}nez Maurel}, Teresa and Georgios Gkiokas and Gomes, {Carlos A.} and Ewen Griffiths and Ali Guner and Sanjay Gupta and Andreas Hecker and Hirano, {Elcio S.} and Adrien Hodonou and Martin Hutan and Orestis Ioannidis and Arda Isik and Georgy Ivakhov and Sumita Jain and Mantas Jokubauskas and Aleksandar Karamarkovic and Saila Kauhanen and Robin Kaushik and Alfie Kavalakat and Jakub Kenig and Vladimir Khokha and Desmond Khor and Dennis Kim and Kim, {Jae I.} and Victor Kong and Konstantinos Lasithiotakis and Pedro Le{\~a}o and Miguel Leon and Andrey Litvin and Varut Lohsiriwat and {L{\'o}pez-Tomassetti Fernandez}, Eudaldo and Eftychios Lostoridis and James Maciel and Piotr Major and Ana Dimova and Dimitrios Manatakis and Athanasio Marinis and Aleix Martinez-Perez and Sanjay Marwah and Michael McFarlane and Cristian Mesina and Micha{\l} Pȩdziwiatr and Nickos Michalopoulos and Evangelos Misiakos and Ali Mohamedahmed and Radu Moldovanu and Giulia Montori and {Mysore Narayana}, Raghuveer and Ionut Negoi and Ioannis Nikolopoulos and Giuseppe Novelli and Viktors Novikovs and Iyiade Olaoye and Abdelkarim Omari and Ordo{\~n}ez, {Carlos A.} and Mouaqit Ouadii and Zeynep Ozkan and Ajay Pal and Palini, {Gian M.} and Partecke, {Lars I.} and Francesco Pata and Micha{\l} Pȩdziwiatr and {Pereira J{\'u}nior}, {Gerson A.} and Tadeja Pintar and Magdalena Pisarska and Ploneda-Valencia, {Cesar F.} and Konstantinos Pouggouras and Vinod Prabhu and Padmakumar Ramakrishnapillai and Regimbeau, {Jean Marc} and Marianne Reitz and Daniel Rios-Cruz and Sten Saar and Boris Sakakushev and Charalampos Seretis and Alexander Sazhin and Vishal Shelat and Matej Skrovina and Dmitry Smirnov and Charalampos Spyropoulos and Marcin Strza{\l}ka and Peep Talving and {Teixeira Gonsaga}, {Ricardo A.} and George Theobald and Gia Tomadze and Myftar Torba and Cristian Tran{\`a} and Jan Ulrych and Uzunoğlu, {Mustafa Y.} and Alin Vasilescu and Savino Occhionorelli and Aur{\'e}lien Venara and Andras Vereczkei and Nereo Vettoretto and Nutu Vlad and Maciej Walȩdziak and Yilmaz, {Tongu{\c c} U.} and Yuan, {Kuo Ching} and Cui Yunfeng and Justas Zilinskas and G{\'e}rard Grelpois and Fausto Catena",

year = "2018",

month = apr,

day = "16",

doi = "10.1186/s13017-018-0179-0",

language = "English",

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journal = "World Journal of Emergency Surgery",

issn = "1749-7922",

publisher = "BioMed Central",

number = "1",

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TY - JOUR

T1 - Prospective Observational Study on acute Appendicitis Worldwide (POSAW)

AU - Sartelli, Massimo

AU - Baiocchi, Gian L.

AU - Di Saverio, Salomone

AU - Ferrara, Francesco

AU - Labricciosa, Francesco M.

AU - Ansaloni, Luca

AU - Coccolini, Federico

AU - Vijayan, Deepak

AU - Abbas, Ashraf

AU - Abongwa, Hariscine K.

AU - Agboola, John

AU - Ahmed, Adamu

AU - Akhmeteli, Lali

AU - Akkapulu, Nezih

AU - Akkucuk, Seckin

AU - Altintoprak, Fatih

AU - Andreiev, Aurelia L.

AU - Anyfantakis, Dimitrios

AU - Atanasov, Boiko

AU - Bala, Miklosh

AU - Balalis, Dimitrios

AU - Baraket, Oussama

AU - Bellanova, Giovanni

AU - Beltran, Marcelo

AU - Melo, Renato Bessa

AU - Bini, Roberto

AU - Bouliaris, Konstantinos

AU - Brunelli, Daniele

AU - Castillo, Adrian

AU - Catani, Marco

AU - Che Jusoh, Asri

AU - Chichom-Mefire, Alain

AU - Cocorullo, Gianfranco

AU - Coimbra, Raul

AU - Colak, Elif

AU - Costa, Silvia

AU - Das, Koray

AU - Delibegovic, Samir

AU - Demetrashvili, Zaza

AU - Di Carlo, Isidoro

AU - Kiseleva, Nadezda

AU - El Zalabany, Tamer

AU - Faro, Mario

AU - Ferreira, Margarida

AU - Fraga, Gustavo P.

AU - Gachabayov, Mahir

AU - Ghnnam, Wagih M.

AU - Giménez Maurel, Teresa

AU - Gkiokas, Georgios

AU - Gomes, Carlos A.

AU - Griffiths, Ewen

AU - Guner, Ali

AU - Gupta, Sanjay

AU - Hecker, Andreas

AU - Hirano, Elcio S.

AU - Hodonou, Adrien

AU - Hutan, Martin

AU - Ioannidis, Orestis

AU - Isik, Arda

AU - Ivakhov, Georgy

AU - Jain, Sumita

AU - Jokubauskas, Mantas

AU - Karamarkovic, Aleksandar

AU - Kauhanen, Saila

AU - Kaushik, Robin

AU - Kavalakat, Alfie

AU - Kenig, Jakub

AU - Khokha, Vladimir

AU - Khor, Desmond

AU - Kim, Dennis

AU - Kim, Jae I.

AU - Kong, Victor

AU - Lasithiotakis, Konstantinos

AU - Leão, Pedro

AU - Leon, Miguel

AU - Litvin, Andrey

AU - Lohsiriwat, Varut

AU - López-Tomassetti Fernandez, Eudaldo

AU - Lostoridis, Eftychios

AU - Maciel, James

AU - Major, Piotr

AU - Dimova, Ana

AU - Manatakis, Dimitrios

AU - Marinis, Athanasio

AU - Martinez-Perez, Aleix

AU - Marwah, Sanjay

AU - McFarlane, Michael

AU - Mesina, Cristian

AU - Pȩdziwiatr, Michał

AU - Michalopoulos, Nickos

AU - Misiakos, Evangelos

AU - Mohamedahmed, Ali

AU - Moldovanu, Radu

AU - Montori, Giulia

AU - Mysore Narayana, Raghuveer

AU - Negoi, Ionut

AU - Nikolopoulos, Ioannis

AU - Novelli, Giuseppe

AU - Novikovs, Viktors

AU - Olaoye, Iyiade

AU - Omari, Abdelkarim

AU - Ordoñez, Carlos A.

AU - Ouadii, Mouaqit

AU - Ozkan, Zeynep

AU - Pal, Ajay

AU - Palini, Gian M.

AU - Partecke, Lars I.

AU - Pata, Francesco

AU - Pȩdziwiatr, Michał

AU - Pereira Júnior, Gerson A.

AU - Pintar, Tadeja

AU - Pisarska, Magdalena

AU - Ploneda-Valencia, Cesar F.

AU - Pouggouras, Konstantinos

AU - Prabhu, Vinod

AU - Ramakrishnapillai, Padmakumar

AU - Regimbeau, Jean Marc

AU - Reitz, Marianne

AU - Rios-Cruz, Daniel

AU - Saar, Sten

AU - Sakakushev, Boris

AU - Seretis, Charalampos

AU - Sazhin, Alexander

AU - Shelat, Vishal

AU - Skrovina, Matej

AU - Smirnov, Dmitry

AU - Spyropoulos, Charalampos

AU - Strzałka, Marcin

AU - Talving, Peep

AU - Teixeira Gonsaga, Ricardo A.

AU - Theobald, George

AU - Tomadze, Gia

AU - Torba, Myftar

AU - Tranà, Cristian

AU - Ulrych, Jan

AU - Uzunoğlu, Mustafa Y.

AU - Vasilescu, Alin

AU - Occhionorelli, Savino

AU - Venara, Aurélien

AU - Vereczkei, Andras

AU - Vettoretto, Nereo

AU - Vlad, Nutu

AU - Walȩdziak, Maciej

AU - Yilmaz, Tonguç U.

AU - Yuan, Kuo Ching

AU - Yunfeng, Cui

AU - Zilinskas, Justas

AU - Grelpois, Gérard

AU - Catena, Fausto

PY - 2018/4/16

Y1 - 2018/4/16

N2 - Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments. Methods: This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016-September 30, 2016). All consecutive patients admitted to surgical departments with a clinical diagnosis of AA were included in the study. Results: A total of 4282 patients were enrolled in the POSAW study, 1928 (45%) women and 2354 (55%) men, with a median age of 29 years. Nine hundred and seven (21.2%) patients underwent an abdominal CT scan, 1856 (43.3%) patients an US, and 285 (6.7%) patients both CT scan and US. A total of 4097 (95.7%) patients underwent surgery; 1809 (42.2%) underwent open appendectomy and 2215 (51.7%) had laparoscopic appendectomy. One hundred eighty-five (4.3%) patients were managed conservatively. Major complications occurred in 199 patients (4.6%). The overall mortality rate was 0.28%. Conclusions: The results of the present study confirm the clinical value of imaging techniques and prognostic scores. Appendectomy remains the most effective treatment of acute appendicitis. Mortality rate is low.

AB - Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments. Methods: This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016-September 30, 2016). All consecutive patients admitted to surgical departments with a clinical diagnosis of AA were included in the study. Results: A total of 4282 patients were enrolled in the POSAW study, 1928 (45%) women and 2354 (55%) men, with a median age of 29 years. Nine hundred and seven (21.2%) patients underwent an abdominal CT scan, 1856 (43.3%) patients an US, and 285 (6.7%) patients both CT scan and US. A total of 4097 (95.7%) patients underwent surgery; 1809 (42.2%) underwent open appendectomy and 2215 (51.7%) had laparoscopic appendectomy. One hundred eighty-five (4.3%) patients were managed conservatively. Major complications occurred in 199 patients (4.6%). The overall mortality rate was 0.28%. Conclusions: The results of the present study confirm the clinical value of imaging techniques and prognostic scores. Appendectomy remains the most effective treatment of acute appendicitis. Mortality rate is low.

KW - Acute appendicitis

KW - Antibiotics

KW - Diagnosis

KW - Management

KW - Surgery

UR - http://www.scopus.com/inward/record.url?scp=85045390535&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85045390535&partnerID=8YFLogxK

U2 - 10.1186/s13017-018-0179-0

DO - 10.1186/s13017-018-0179-0

M3 - Article

C2 - 29686725

AN - SCOPUS:85045390535

VL - 13

JO - World Journal of Emergency Surgery

JF - World Journal of Emergency Surgery

SN - 1749-7922

IS - 1

M1 - 19

ER -