Abstract
Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments. Methods: This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016-September 30, 2016). All consecutive patients admitted to surgical departments with a clinical diagnosis of AA were included in the study. Results: A total of 4282 patients were enrolled in the POSAW study, 1928 (45%) women and 2354 (55%) men, with a median age of 29 years. Nine hundred and seven (21.2%) patients underwent an abdominal CT scan, 1856 (43.3%) patients an US, and 285 (6.7%) patients both CT scan and US. A total of 4097 (95.7%) patients underwent surgery; 1809 (42.2%) underwent open appendectomy and 2215 (51.7%) had laparoscopic appendectomy. One hundred eighty-five (4.3%) patients were managed conservatively. Major complications occurred in 199 patients (4.6%). The overall mortality rate was 0.28%. Conclusions: The results of the present study confirm the clinical value of imaging techniques and prognostic scores. Appendectomy remains the most effective treatment of acute appendicitis. Mortality rate is low.
| Original language | English |
|---|---|
| Article number | 19 |
| Journal | World Journal of Emergency Surgery |
| Volume | 13 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Apr 16 2018 |
| Externally published | Yes |
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Keywords
- Acute appendicitis
- Antibiotics
- Diagnosis
- Management
- Surgery
ASJC Scopus subject areas
- Surgery
- Emergency Medicine
Cite this
Prospective Observational Study on acute Appendicitis Worldwide (POSAW). / Sartelli, Massimo; Baiocchi, Gian L.; Di Saverio, Salomone; Ferrara, Francesco; Labricciosa, Francesco M.; Ansaloni, Luca; Coccolini, Federico; Vijayan, Deepak; Abbas, Ashraf; Abongwa, Hariscine K.; Agboola, John; Ahmed, Adamu; Akhmeteli, Lali; Akkapulu, Nezih; Akkucuk, Seckin; Altintoprak, Fatih; Andreiev, Aurelia L.; Anyfantakis, Dimitrios; Atanasov, Boiko; Bala, Miklosh; Balalis, Dimitrios; Baraket, Oussama; Bellanova, Giovanni; Beltran, Marcelo; Melo, Renato Bessa; Bini, Roberto; Bouliaris, Konstantinos; Brunelli, Daniele; Castillo, Adrian; Catani, Marco; Che Jusoh, Asri; Chichom-Mefire, Alain; Cocorullo, Gianfranco; Coimbra, Raul; Colak, Elif; Costa, Silvia; Das, Koray; Delibegovic, Samir; Demetrashvili, Zaza; Di Carlo, Isidoro; Kiseleva, Nadezda; El Zalabany, Tamer; Faro, Mario; Ferreira, Margarida; Fraga, Gustavo P.; Gachabayov, Mahir; Ghnnam, Wagih M.; Giménez Maurel, Teresa; Gkiokas, Georgios; Gomes, Carlos A.; Griffiths, Ewen; Guner, Ali; Gupta, Sanjay; Hecker, Andreas; Hirano, Elcio S.; Hodonou, Adrien; Hutan, Martin; Ioannidis, Orestis; Isik, Arda; Ivakhov, Georgy; Jain, Sumita; Jokubauskas, Mantas; Karamarkovic, Aleksandar; Kauhanen, Saila; Kaushik, Robin; Kavalakat, Alfie; Kenig, Jakub; Khokha, Vladimir; Khor, Desmond; Kim, Dennis; Kim, Jae I.; Kong, Victor; Lasithiotakis, Konstantinos; Leão, Pedro; Leon, Miguel; Litvin, Andrey; Lohsiriwat, Varut; López-Tomassetti Fernandez, Eudaldo; Lostoridis, Eftychios; Maciel, James; Major, Piotr; Dimova, Ana; Manatakis, Dimitrios; Marinis, Athanasio; Martinez-Perez, Aleix; Marwah, Sanjay; McFarlane, Michael; Mesina, Cristian; Pȩdziwiatr, Michał; Michalopoulos, Nickos; Misiakos, Evangelos; Mohamedahmed, Ali; Moldovanu, Radu; Montori, Giulia; Mysore Narayana, Raghuveer; Negoi, Ionut; Nikolopoulos, Ioannis; Novelli, Giuseppe; Novikovs, Viktors; Olaoye, Iyiade; Omari, Abdelkarim; Ordoñez, Carlos A.; Ouadii, Mouaqit; Ozkan, Zeynep; Pal, Ajay; Palini, Gian M.; Partecke, Lars I.; Pata, Francesco; Pȩdziwiatr, Michał; Pereira Júnior, Gerson A.; Pintar, Tadeja; Pisarska, Magdalena; Ploneda-Valencia, Cesar F.; Pouggouras, Konstantinos; Prabhu, Vinod; Ramakrishnapillai, Padmakumar; Regimbeau, Jean Marc; Reitz, Marianne; Rios-Cruz, Daniel; Saar, Sten; Sakakushev, Boris; Seretis, Charalampos; Sazhin, Alexander; Shelat, Vishal; Skrovina, Matej; Smirnov, Dmitry; Spyropoulos, Charalampos; Strzałka, Marcin; Talving, Peep; Teixeira Gonsaga, Ricardo A.; Theobald, George; Tomadze, Gia; Torba, Myftar; Tranà, Cristian; Ulrych, Jan; Uzunoğlu, Mustafa Y.; Vasilescu, Alin; Occhionorelli, Savino; Venara, Aurélien; Vereczkei, Andras; Vettoretto, Nereo; Vlad, Nutu; Walȩdziak, Maciej; Yilmaz, Tonguç U.; Yuan, Kuo Ching; Yunfeng, Cui; Zilinskas, Justas; Grelpois, Gérard; Catena, Fausto.
In: World Journal of Emergency Surgery, Vol. 13, No. 1, 19, 16.04.2018.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prospective Observational Study on acute Appendicitis Worldwide (POSAW)
AU - Sartelli, Massimo
AU - Baiocchi, Gian L.
AU - Di Saverio, Salomone
AU - Ferrara, Francesco
AU - Labricciosa, Francesco M.
AU - Ansaloni, Luca
AU - Coccolini, Federico
AU - Vijayan, Deepak
AU - Abbas, Ashraf
AU - Abongwa, Hariscine K.
AU - Agboola, John
AU - Ahmed, Adamu
AU - Akhmeteli, Lali
AU - Akkapulu, Nezih
AU - Akkucuk, Seckin
AU - Altintoprak, Fatih
AU - Andreiev, Aurelia L.
AU - Anyfantakis, Dimitrios
AU - Atanasov, Boiko
AU - Bala, Miklosh
AU - Balalis, Dimitrios
AU - Baraket, Oussama
AU - Bellanova, Giovanni
AU - Beltran, Marcelo
AU - Melo, Renato Bessa
AU - Bini, Roberto
AU - Bouliaris, Konstantinos
AU - Brunelli, Daniele
AU - Castillo, Adrian
AU - Catani, Marco
AU - Che Jusoh, Asri
AU - Chichom-Mefire, Alain
AU - Cocorullo, Gianfranco
AU - Coimbra, Raul
AU - Colak, Elif
AU - Costa, Silvia
AU - Das, Koray
AU - Delibegovic, Samir
AU - Demetrashvili, Zaza
AU - Di Carlo, Isidoro
AU - Kiseleva, Nadezda
AU - El Zalabany, Tamer
AU - Faro, Mario
AU - Ferreira, Margarida
AU - Fraga, Gustavo P.
AU - Gachabayov, Mahir
AU - Ghnnam, Wagih M.
AU - Giménez Maurel, Teresa
AU - Gkiokas, Georgios
AU - Gomes, Carlos A.
AU - Griffiths, Ewen
AU - Guner, Ali
AU - Gupta, Sanjay
AU - Hecker, Andreas
AU - Hirano, Elcio S.
AU - Hodonou, Adrien
AU - Hutan, Martin
AU - Ioannidis, Orestis
AU - Isik, Arda
AU - Ivakhov, Georgy
AU - Jain, Sumita
AU - Jokubauskas, Mantas
AU - Karamarkovic, Aleksandar
AU - Kauhanen, Saila
AU - Kaushik, Robin
AU - Kavalakat, Alfie
AU - Kenig, Jakub
AU - Khokha, Vladimir
AU - Khor, Desmond
AU - Kim, Dennis
AU - Kim, Jae I.
AU - Kong, Victor
AU - Lasithiotakis, Konstantinos
AU - Leão, Pedro
AU - Leon, Miguel
AU - Litvin, Andrey
AU - Lohsiriwat, Varut
AU - López-Tomassetti Fernandez, Eudaldo
AU - Lostoridis, Eftychios
AU - Maciel, James
AU - Major, Piotr
AU - Dimova, Ana
AU - Manatakis, Dimitrios
AU - Marinis, Athanasio
AU - Martinez-Perez, Aleix
AU - Marwah, Sanjay
AU - McFarlane, Michael
AU - Mesina, Cristian
AU - Pȩdziwiatr, Michał
AU - Michalopoulos, Nickos
AU - Misiakos, Evangelos
AU - Mohamedahmed, Ali
AU - Moldovanu, Radu
AU - Montori, Giulia
AU - Mysore Narayana, Raghuveer
AU - Negoi, Ionut
AU - Nikolopoulos, Ioannis
AU - Novelli, Giuseppe
AU - Novikovs, Viktors
AU - Olaoye, Iyiade
AU - Omari, Abdelkarim
AU - Ordoñez, Carlos A.
AU - Ouadii, Mouaqit
AU - Ozkan, Zeynep
AU - Pal, Ajay
AU - Palini, Gian M.
AU - Partecke, Lars I.
AU - Pata, Francesco
AU - Pȩdziwiatr, Michał
AU - Pereira Júnior, Gerson A.
AU - Pintar, Tadeja
AU - Pisarska, Magdalena
AU - Ploneda-Valencia, Cesar F.
AU - Pouggouras, Konstantinos
AU - Prabhu, Vinod
AU - Ramakrishnapillai, Padmakumar
AU - Regimbeau, Jean Marc
AU - Reitz, Marianne
AU - Rios-Cruz, Daniel
AU - Saar, Sten
AU - Sakakushev, Boris
AU - Seretis, Charalampos
AU - Sazhin, Alexander
AU - Shelat, Vishal
AU - Skrovina, Matej
AU - Smirnov, Dmitry
AU - Spyropoulos, Charalampos
AU - Strzałka, Marcin
AU - Talving, Peep
AU - Teixeira Gonsaga, Ricardo A.
AU - Theobald, George
AU - Tomadze, Gia
AU - Torba, Myftar
AU - Tranà, Cristian
AU - Ulrych, Jan
AU - Uzunoğlu, Mustafa Y.
AU - Vasilescu, Alin
AU - Occhionorelli, Savino
AU - Venara, Aurélien
AU - Vereczkei, Andras
AU - Vettoretto, Nereo
AU - Vlad, Nutu
AU - Walȩdziak, Maciej
AU - Yilmaz, Tonguç U.
AU - Yuan, Kuo Ching
AU - Yunfeng, Cui
AU - Zilinskas, Justas
AU - Grelpois, Gérard
AU - Catena, Fausto
PY - 2018/4/16
Y1 - 2018/4/16
N2 - Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments. Methods: This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016-September 30, 2016). All consecutive patients admitted to surgical departments with a clinical diagnosis of AA were included in the study. Results: A total of 4282 patients were enrolled in the POSAW study, 1928 (45%) women and 2354 (55%) men, with a median age of 29 years. Nine hundred and seven (21.2%) patients underwent an abdominal CT scan, 1856 (43.3%) patients an US, and 285 (6.7%) patients both CT scan and US. A total of 4097 (95.7%) patients underwent surgery; 1809 (42.2%) underwent open appendectomy and 2215 (51.7%) had laparoscopic appendectomy. One hundred eighty-five (4.3%) patients were managed conservatively. Major complications occurred in 199 patients (4.6%). The overall mortality rate was 0.28%. Conclusions: The results of the present study confirm the clinical value of imaging techniques and prognostic scores. Appendectomy remains the most effective treatment of acute appendicitis. Mortality rate is low.
AB - Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments. Methods: This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016-September 30, 2016). All consecutive patients admitted to surgical departments with a clinical diagnosis of AA were included in the study. Results: A total of 4282 patients were enrolled in the POSAW study, 1928 (45%) women and 2354 (55%) men, with a median age of 29 years. Nine hundred and seven (21.2%) patients underwent an abdominal CT scan, 1856 (43.3%) patients an US, and 285 (6.7%) patients both CT scan and US. A total of 4097 (95.7%) patients underwent surgery; 1809 (42.2%) underwent open appendectomy and 2215 (51.7%) had laparoscopic appendectomy. One hundred eighty-five (4.3%) patients were managed conservatively. Major complications occurred in 199 patients (4.6%). The overall mortality rate was 0.28%. Conclusions: The results of the present study confirm the clinical value of imaging techniques and prognostic scores. Appendectomy remains the most effective treatment of acute appendicitis. Mortality rate is low.
KW - Acute appendicitis
KW - Antibiotics
KW - Diagnosis
KW - Management
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=85045390535&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85045390535&partnerID=8YFLogxK
U2 - 10.1186/s13017-018-0179-0
DO - 10.1186/s13017-018-0179-0
M3 - Article
C2 - 29686725
AN - SCOPUS:85045390535
VL - 13
JO - World Journal of Emergency Surgery
JF - World Journal of Emergency Surgery
SN - 1749-7922
IS - 1
M1 - 19
ER -