Prorocentin, a new polyketide from the marine dinoflagellate Prorocentrum lima

Chung Kuang Lu, Hong Nong Chou, Ching Kuo Lee, Zong-Huei Li

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(Chemical Equation Presented) Prorocentin (1), isolated from an okadaic acid-producing organism, Prorocentrum lima, possessed all-trans trienes, an epoxide, as well as the 6/6/6-trans-fused/spiro-linked polyether ring moieties. The unique structure supports the proposed cyclization mechanism, polyene formation, epoxidation, and cyclization, of marine polyether toxins. The relative stereostructure was determined on the basis of spectral data.

Original languageEnglish
Pages (from-to)3893-3896
Number of pages4
JournalOrganic Letters
Issue number18
Publication statusPublished - Sep 1 2005


ASJC Scopus subject areas

  • Molecular Medicine

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