Prorocentin, a new polyketide from the marine dinoflagellate Prorocentrum lima

Chung Kuang Lu, Hong Nong Chou, Ching Kuo Lee, Zong-Huei Li

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

(Chemical Equation Presented) Prorocentin (1), isolated from an okadaic acid-producing organism, Prorocentrum lima, possessed all-trans trienes, an epoxide, as well as the 6/6/6-trans-fused/spiro-linked polyether ring moieties. The unique structure supports the proposed cyclization mechanism, polyene formation, epoxidation, and cyclization, of marine polyether toxins. The relative stereostructure was determined on the basis of spectral data.

Original languageEnglish
Pages (from-to)3893-3896
Number of pages4
JournalOrganic Letters
Volume7
Issue number18
DOIs
Publication statusPublished - Sep 1 2005

Fingerprint

trienes
Polyketides
Dinoflagellida
epoxidation
epoxy compounds
Polyethers
Cyclization
organisms
Marine Toxins
Polyenes
Okadaic Acid
acids
Epoxidation
rings
Epoxy Compounds
prorocentin

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Prorocentin, a new polyketide from the marine dinoflagellate Prorocentrum lima. / Lu, Chung Kuang; Chou, Hong Nong; Lee, Ching Kuo; Li, Zong-Huei.

In: Organic Letters, Vol. 7, No. 18, 01.09.2005, p. 3893-3896.

Research output: Contribution to journalArticle

Lu, Chung Kuang ; Chou, Hong Nong ; Lee, Ching Kuo ; Li, Zong-Huei. / Prorocentin, a new polyketide from the marine dinoflagellate Prorocentrum lima. In: Organic Letters. 2005 ; Vol. 7, No. 18. pp. 3893-3896.
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