Prominent vessel sign on susceptibility-weighted imaging in acute stroke: Prediction of infarct growth and clinical outcome

Chia Yuen Chen, Chin I. Chen, Fong Y. Tsai, Ping Huei Tsai, Wing P. Chan

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Background and Purpose Predicting the risk of further infarct growth in stroke patients is critical to therapeutic decision making. We aimed to predict early infarct growth and clinical outcome from prominent vessel sign (PVS) identified on the first susceptibility-weighted image (SWI) after acute stroke. Materials and Methods Twenty-two patients with middle cerebral artery (MCA) infarction had diffusion-weighted imaging, SWI, MR angiography, and clinical evaluation using the National Institutes of Health Stroke Scale at 760 hours and 514 days after stroke onset. Late-stage clinical evaluation at 1 and 3 months used the modified Rankin Scale. The infarct area and growth were scored from 10 (none) to 0 (infarct or growth in all 10 zones) using the Alberta Stroke Program Early CT Score (ASPECTS) system. Results Infarct growth on the second MRI occurred in 13 of 15 patients with PVS on the first MRI and not in any patient without PVS (n=7; r=0.86, P

Original languageEnglish
Article numbere0131118
JournalPLoS One
Volume10
Issue number6
DOIs
Publication statusPublished - Jun 25 2015

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infarction
stroke
Stroke
image analysis
Imaging techniques
prediction
Growth
Magnetic resonance imaging
Alberta
Angiography
Middle Cerebral Artery Infarction
National Institutes of Health
National Institutes of Health (U.S.)
Decision Making
arteries
Decision making
Health
decision making
therapeutics

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Prominent vessel sign on susceptibility-weighted imaging in acute stroke : Prediction of infarct growth and clinical outcome. / Chen, Chia Yuen; Chen, Chin I.; Tsai, Fong Y.; Tsai, Ping Huei; Chan, Wing P.

In: PLoS One, Vol. 10, No. 6, e0131118, 25.06.2015.

Research output: Contribution to journalArticle

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