Prolonged injection time and light smoking decrease the incidence of fentanyl-induced cough

Jui A. Lin, Chun Chang Yeh, Meei Shyuan Lee, Ching Tang Wu, Shinn Long Lin, Chih Shung Wong

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

We designed this study to evaluate the effect of injection time and smoking on fentanyl-induced cough. Four-hundred-fifty ASA class I-II patients, aged 18-80 yr and weighing 40-90 kg, scheduled for elective surgery were included. All patients received fentanyl (100 μg for patients weighing 40-69 kg and 150 μg for patients weighing 70-90 kg for clinical convenience) via the proximal port of a peripheral IV line on the forearm. Patients were randomly assigned to 3 groups of 150 patients each. Patients in Group I received fentanyl injection over 2 s, whereas for patients in Groups II and III the fentanyl was injected at a constant rate over 15 s and 30 s, respectively. We recorded the number of coughs of each patient during and 30 s after fentanyl injection. The incidence of cough was 18% in group I, 8% in Group II, and 1.3% in Group III, significantly less (P <0.05) with a longer injection time. Current smokers had a less frequent incidence of cough than nonsmokers; however, this effect was only significant in light smokers (

Original languageEnglish
Pages (from-to)670-674
Number of pages5
JournalAnesthesia and Analgesia
Volume101
Issue number3
DOIs
Publication statusPublished - Sep 2005
Externally publishedYes

Fingerprint

Fentanyl
Cough
Smoking
Light
Injections
Incidence
Forearm

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Prolonged injection time and light smoking decrease the incidence of fentanyl-induced cough. / Lin, Jui A.; Yeh, Chun Chang; Lee, Meei Shyuan; Wu, Ching Tang; Lin, Shinn Long; Wong, Chih Shung.

In: Anesthesia and Analgesia, Vol. 101, No. 3, 09.2005, p. 670-674.

Research output: Contribution to journalArticle

Lin, Jui A. ; Yeh, Chun Chang ; Lee, Meei Shyuan ; Wu, Ching Tang ; Lin, Shinn Long ; Wong, Chih Shung. / Prolonged injection time and light smoking decrease the incidence of fentanyl-induced cough. In: Anesthesia and Analgesia. 2005 ; Vol. 101, No. 3. pp. 670-674.
@article{04d481b891964881879a85a7a582f46f,
title = "Prolonged injection time and light smoking decrease the incidence of fentanyl-induced cough",
abstract = "We designed this study to evaluate the effect of injection time and smoking on fentanyl-induced cough. Four-hundred-fifty ASA class I-II patients, aged 18-80 yr and weighing 40-90 kg, scheduled for elective surgery were included. All patients received fentanyl (100 μg for patients weighing 40-69 kg and 150 μg for patients weighing 70-90 kg for clinical convenience) via the proximal port of a peripheral IV line on the forearm. Patients were randomly assigned to 3 groups of 150 patients each. Patients in Group I received fentanyl injection over 2 s, whereas for patients in Groups II and III the fentanyl was injected at a constant rate over 15 s and 30 s, respectively. We recorded the number of coughs of each patient during and 30 s after fentanyl injection. The incidence of cough was 18{\%} in group I, 8{\%} in Group II, and 1.3{\%} in Group III, significantly less (P <0.05) with a longer injection time. Current smokers had a less frequent incidence of cough than nonsmokers; however, this effect was only significant in light smokers (",
author = "Lin, {Jui A.} and Yeh, {Chun Chang} and Lee, {Meei Shyuan} and Wu, {Ching Tang} and Lin, {Shinn Long} and Wong, {Chih Shung}",
year = "2005",
month = "9",
doi = "10.1213/01.ANE.0000159161.31276.DB",
language = "English",
volume = "101",
pages = "670--674",
journal = "Anesthesia and Analgesia",
issn = "0003-2999",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Prolonged injection time and light smoking decrease the incidence of fentanyl-induced cough

AU - Lin, Jui A.

AU - Yeh, Chun Chang

AU - Lee, Meei Shyuan

AU - Wu, Ching Tang

AU - Lin, Shinn Long

AU - Wong, Chih Shung

PY - 2005/9

Y1 - 2005/9

N2 - We designed this study to evaluate the effect of injection time and smoking on fentanyl-induced cough. Four-hundred-fifty ASA class I-II patients, aged 18-80 yr and weighing 40-90 kg, scheduled for elective surgery were included. All patients received fentanyl (100 μg for patients weighing 40-69 kg and 150 μg for patients weighing 70-90 kg for clinical convenience) via the proximal port of a peripheral IV line on the forearm. Patients were randomly assigned to 3 groups of 150 patients each. Patients in Group I received fentanyl injection over 2 s, whereas for patients in Groups II and III the fentanyl was injected at a constant rate over 15 s and 30 s, respectively. We recorded the number of coughs of each patient during and 30 s after fentanyl injection. The incidence of cough was 18% in group I, 8% in Group II, and 1.3% in Group III, significantly less (P <0.05) with a longer injection time. Current smokers had a less frequent incidence of cough than nonsmokers; however, this effect was only significant in light smokers (

AB - We designed this study to evaluate the effect of injection time and smoking on fentanyl-induced cough. Four-hundred-fifty ASA class I-II patients, aged 18-80 yr and weighing 40-90 kg, scheduled for elective surgery were included. All patients received fentanyl (100 μg for patients weighing 40-69 kg and 150 μg for patients weighing 70-90 kg for clinical convenience) via the proximal port of a peripheral IV line on the forearm. Patients were randomly assigned to 3 groups of 150 patients each. Patients in Group I received fentanyl injection over 2 s, whereas for patients in Groups II and III the fentanyl was injected at a constant rate over 15 s and 30 s, respectively. We recorded the number of coughs of each patient during and 30 s after fentanyl injection. The incidence of cough was 18% in group I, 8% in Group II, and 1.3% in Group III, significantly less (P <0.05) with a longer injection time. Current smokers had a less frequent incidence of cough than nonsmokers; however, this effect was only significant in light smokers (

UR - http://www.scopus.com/inward/record.url?scp=23944509218&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=23944509218&partnerID=8YFLogxK

U2 - 10.1213/01.ANE.0000159161.31276.DB

DO - 10.1213/01.ANE.0000159161.31276.DB

M3 - Article

C2 - 16115973

AN - SCOPUS:23944509218

VL - 101

SP - 670

EP - 674

JO - Anesthesia and Analgesia

JF - Anesthesia and Analgesia

SN - 0003-2999

IS - 3

ER -