Progression of cytomegalovirus retinitis in acquired immunodeficiency syndrome

A case report

Shih Hwa Chiou, Wing Wai Wong, Wen-Ming Hsu, Yu Mei Chung, Cheng Yi Liu, Wu Tse Liu, Shou Chien Chen, Jorn Hon Liu

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We report an AIDS patient with cytomegalovirus (CMV) retinitis that developed from an early minor lesion and progressed to extended involvement of the retina and severe deterioration of vision due to poor compliance with ganciclovir treatment. A 33-year-old man was known to have acquired immunodeficiency syndrome (AIDS) for eight months. The patient had no complaint of visual symptoms. A routine eye examination revealed his visual acuity to be 6/6 in both eyes. The dilated eye fundus examination using indirect ophthalmoscopy disclosed a localized white yellowish granular lesion in the peripheral retina of the right eye and a completely normal left eye. CMV retinitis with initial manifestation in the right eye was diagnosed. Due to incomplete treatment with ganciclovir, the retinal lesion rapidly enlarged and extended to the posterior pole, with eventual destruction of the nerve fiber layer and optic disc. The visual acuity of right eye dropped from 6/6 to 1/60 within six months. This case report indicates the importance of early, dilated eye fundus examination and recognition of early CMV retinitis in order to salvage visual function in AIDS patients. Completion of the anti- CMV treatment course in halting the progression of CMV retinitis is also emphasized.

Original languageEnglish
Pages (from-to)316-321
Number of pages6
JournalChinese Medical Journal (Taipei)
Volume62
Issue number5
Publication statusPublished - May 1 1999
Externally publishedYes

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Cytomegalovirus Retinitis
Acquired Immunodeficiency Syndrome
Ganciclovir
Visual Acuity
Retina
Ophthalmoscopy
Optic Disk
Cytomegalovirus
Nerve Fibers
Therapeutics

Keywords

  • Acquired immunodeficiency syndrome
  • Cytomegalovirus retinitis
  • Fundus examination

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Chiou, S. H., Wong, W. W., Hsu, W-M., Chung, Y. M., Liu, C. Y., Liu, W. T., ... Liu, J. H. (1999). Progression of cytomegalovirus retinitis in acquired immunodeficiency syndrome: A case report. Chinese Medical Journal (Taipei), 62(5), 316-321.

Progression of cytomegalovirus retinitis in acquired immunodeficiency syndrome : A case report. / Chiou, Shih Hwa; Wong, Wing Wai; Hsu, Wen-Ming; Chung, Yu Mei; Liu, Cheng Yi; Liu, Wu Tse; Chen, Shou Chien; Liu, Jorn Hon.

In: Chinese Medical Journal (Taipei), Vol. 62, No. 5, 01.05.1999, p. 316-321.

Research output: Contribution to journalArticle

Chiou, SH, Wong, WW, Hsu, W-M, Chung, YM, Liu, CY, Liu, WT, Chen, SC & Liu, JH 1999, 'Progression of cytomegalovirus retinitis in acquired immunodeficiency syndrome: A case report', Chinese Medical Journal (Taipei), vol. 62, no. 5, pp. 316-321.
Chiou, Shih Hwa ; Wong, Wing Wai ; Hsu, Wen-Ming ; Chung, Yu Mei ; Liu, Cheng Yi ; Liu, Wu Tse ; Chen, Shou Chien ; Liu, Jorn Hon. / Progression of cytomegalovirus retinitis in acquired immunodeficiency syndrome : A case report. In: Chinese Medical Journal (Taipei). 1999 ; Vol. 62, No. 5. pp. 316-321.
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