Prognostic indicators for survival after curative resection for patients with carcinoma of the stomach

Chew Wun Wu, Mao-Chih Hsieh, Su Shun Lo, Shyh Haw Tsay, Anna F.Y. Li, Wing Yiu Lui, Fang Ku P'Eng

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

This study aims to determine prognostic indicators among patient-, tumor-, and treatment-related factors of gastric cancer patients. A total of 510 patients who underwent curative gastric resection were studied. Univariate analysis of patient-related factors showed a significantly lower survival in patients with a history of obstruction, hypoalbuminemia, and anemia. Tumor-related factors including gross appearance, location, and size of tumor; depth of cancer invasion; level, number, and frequency of lymph node metastasis; stromal reaction and tumor growth pattern; and histological classfication all significantly affected survival. Surgical treatment related factors such as total or distal subtotal gastrectomy, extent of lymphadenectomy, and combined resection of adjacent organ(s) showed a statistically significant adverse influence on survival. Multivariate analysis identified only four tumor-related factors - number of metastatic lymph nodes, depth of cancer invasion, stromal reaction, and gross appearance of the tumor - as independently, affecting survival. These findings suggest that only four tumor-related factors were prognostic indicators in patients with gastric cancer.

Original languageEnglish
Pages (from-to)1265-1269
Number of pages5
JournalDigestive Diseases and Sciences
Volume42
Issue number6
DOIs
Publication statusPublished - Aug 27 1997
Externally publishedYes

Fingerprint

Stomach
Carcinoma
Survival
Neoplasms
Stomach Neoplasms
Lymph Nodes
Hypoalbuminemia
Gastrectomy
Lymph Node Excision
Anemia
Multivariate Analysis
Neoplasm Metastasis
Therapeutics
Growth

Keywords

  • Gastrectomy
  • Gastric cancer
  • Prognosis
  • Survival

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology

Cite this

Prognostic indicators for survival after curative resection for patients with carcinoma of the stomach. / Wu, Chew Wun; Hsieh, Mao-Chih; Lo, Su Shun; Tsay, Shyh Haw; Li, Anna F.Y.; Lui, Wing Yiu; P'Eng, Fang Ku.

In: Digestive Diseases and Sciences, Vol. 42, No. 6, 27.08.1997, p. 1265-1269.

Research output: Contribution to journalArticle

Wu, Chew Wun ; Hsieh, Mao-Chih ; Lo, Su Shun ; Tsay, Shyh Haw ; Li, Anna F.Y. ; Lui, Wing Yiu ; P'Eng, Fang Ku. / Prognostic indicators for survival after curative resection for patients with carcinoma of the stomach. In: Digestive Diseases and Sciences. 1997 ; Vol. 42, No. 6. pp. 1265-1269.
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