Prognostic factors after hepatectomy for hepatocellular carcinoma

F. F. Chou, S. M. Sheen-Chen, C. L. Chen, Y. S. Chen, M. J. Chen

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

During a seven and a half year period from 1985 through June 1992, hepatic resection was carried out on 84 patients with hepatocellular carcinoma. Their ages ranged from 10 to 79, with an average of 55 years. Hepatitis B surface antigen (HbsAg) was positive in 83%, an alfafetoprotein level of more than 20ng/dl was found in 71%, and cirrhosis was noted in 64%. Surgical mortality was 3.6% and hospital mortality 1.2%. The 1-, 3- and 5-year actuarial survival rates, excluding in-hospital deaths, were 74%, 56% and 49%, respectively. The large number of patients operated on in the early stage (52%), and Child's class A (61%) might account for the low surgical mortality and high survival rate. The favorable conditions were identified as follows; no cirrhosis, surgery in the early stage, tumor size less than 5 cm, negative HbsAg and freedom from vascular involvement. Multivariate analysis showed that only negative HbsAg had better survival.

Original languageEnglish
Pages (from-to)419-423
Number of pages5
JournalHepato-Gastroenterology
Volume41
Issue number5
Publication statusPublished - Jan 1 1994
Externally publishedYes

Keywords

  • Hepatocellular carcinoma
  • Prognostic factors
  • Surgery

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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