Prlmary Radiotherapy Treatment Results of Maxillary Sinus Squamous Cell Carcinoma

許 智捷, 雷 德, 鍾 娜娜, 丁 禮莉(Lai-Lei Ting), 邵 文逸(Wen-Yi Shau)

Research output: Contribution to journalArticle

Abstract

Purpose: Evaluating 5-year survival rates of maxillary sinus squamous cell carcinoma treated by different methods.Materials and Methods: From 1997 to 1991, 61 patients of maxillary sinus squamous cell carcinoma were included in our study. There were 11 patients with T3 (18%) disease and 50 patients with T4 (82%) disease. Eighteen patients (29.5%) were treated by radiotherapy alone (RT), 32 patients (52.5%) by combined surgery and radiotherapy (SRT) and 11 patients (18.0%) by combined radiotherapy with intra-arterial 5-FU infusion chemotherapy and antrostomy drainage (CRT).Results: Five-year survival rates were 5.6%, 34.4% and 54.5% in RT, SRT and CRT groups, respectively. Statistical significant difference (p<0.05) of survival rates was noted. Regional neck nodal metastasis at initial diagnosis carried significant worse survival results than initial NO state (7.1% vs. 36.2%, p=0.0003). Multivariate analysis revealed that treatment methods, sex and N stages significantly influenced the 5-year survival rate.Conclusion: Combined treatment was superior to radiotherapy alone in 5-year survival rates.
Original languageEnglish
Pages (from-to)163-170
Number of pages8
Journal放射治療與腫瘤學
Volume5
Issue number3
DOIs
Publication statusPublished - 1998
Externally publishedYes

Fingerprint

Maxillary Sinus
Squamous Cell Carcinoma
Radiotherapy
Survival Rate
Therapeutics
Fluorouracil
Drainage
Neck
Multivariate Analysis
Neoplasm Metastasis
Drug Therapy
Survival

Keywords

  • 放射治療
  • 合併治療
  • 上頷竇
  • 扁平細胞癌
  • Radiotherapy
  • Combined treatment
  • Maxillary sinus
  • Squamous cell carcinoma

Cite this

Prlmary Radiotherapy Treatment Results of Maxillary Sinus Squamous Cell Carcinoma. / 許智捷; 雷德; 鍾娜娜; 丁禮莉(Lai-Lei Ting); 邵文逸(Wen-Yi Shau).

In: 放射治療與腫瘤學, Vol. 5, No. 3, 1998, p. 163-170.

Research output: Contribution to journalArticle

許智捷 ; 雷德 ; 鍾娜娜 ; 丁禮莉(Lai-Lei Ting) ; 邵文逸(Wen-Yi Shau). / Prlmary Radiotherapy Treatment Results of Maxillary Sinus Squamous Cell Carcinoma. In: 放射治療與腫瘤學. 1998 ; Vol. 5, No. 3. pp. 163-170.
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abstract = "Purpose: Evaluating 5-year survival rates of maxillary sinus squamous cell carcinoma treated by different methods.Materials and Methods: From 1997 to 1991, 61 patients of maxillary sinus squamous cell carcinoma were included in our study. There were 11 patients with T3 (18{\%}) disease and 50 patients with T4 (82{\%}) disease. Eighteen patients (29.5{\%}) were treated by radiotherapy alone (RT), 32 patients (52.5{\%}) by combined surgery and radiotherapy (SRT) and 11 patients (18.0{\%}) by combined radiotherapy with intra-arterial 5-FU infusion chemotherapy and antrostomy drainage (CRT).Results: Five-year survival rates were 5.6{\%}, 34.4{\%} and 54.5{\%} in RT, SRT and CRT groups, respectively. Statistical significant difference (p<0.05) of survival rates was noted. Regional neck nodal metastasis at initial diagnosis carried significant worse survival results than initial NO state (7.1{\%} vs. 36.2{\%}, p=0.0003). Multivariate analysis revealed that treatment methods, sex and N stages significantly influenced the 5-year survival rate.Conclusion: Combined treatment was superior to radiotherapy alone in 5-year survival rates.",
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author = "智捷 許 and 德 雷 and 娜娜 鍾 and 丁, {禮莉(Lai-Lei Ting)} and 邵, {文逸(Wen-Yi Shau)}",
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N2 - Purpose: Evaluating 5-year survival rates of maxillary sinus squamous cell carcinoma treated by different methods.Materials and Methods: From 1997 to 1991, 61 patients of maxillary sinus squamous cell carcinoma were included in our study. There were 11 patients with T3 (18%) disease and 50 patients with T4 (82%) disease. Eighteen patients (29.5%) were treated by radiotherapy alone (RT), 32 patients (52.5%) by combined surgery and radiotherapy (SRT) and 11 patients (18.0%) by combined radiotherapy with intra-arterial 5-FU infusion chemotherapy and antrostomy drainage (CRT).Results: Five-year survival rates were 5.6%, 34.4% and 54.5% in RT, SRT and CRT groups, respectively. Statistical significant difference (p<0.05) of survival rates was noted. Regional neck nodal metastasis at initial diagnosis carried significant worse survival results than initial NO state (7.1% vs. 36.2%, p=0.0003). Multivariate analysis revealed that treatment methods, sex and N stages significantly influenced the 5-year survival rate.Conclusion: Combined treatment was superior to radiotherapy alone in 5-year survival rates.

AB - Purpose: Evaluating 5-year survival rates of maxillary sinus squamous cell carcinoma treated by different methods.Materials and Methods: From 1997 to 1991, 61 patients of maxillary sinus squamous cell carcinoma were included in our study. There were 11 patients with T3 (18%) disease and 50 patients with T4 (82%) disease. Eighteen patients (29.5%) were treated by radiotherapy alone (RT), 32 patients (52.5%) by combined surgery and radiotherapy (SRT) and 11 patients (18.0%) by combined radiotherapy with intra-arterial 5-FU infusion chemotherapy and antrostomy drainage (CRT).Results: Five-year survival rates were 5.6%, 34.4% and 54.5% in RT, SRT and CRT groups, respectively. Statistical significant difference (p<0.05) of survival rates was noted. Regional neck nodal metastasis at initial diagnosis carried significant worse survival results than initial NO state (7.1% vs. 36.2%, p=0.0003). Multivariate analysis revealed that treatment methods, sex and N stages significantly influenced the 5-year survival rate.Conclusion: Combined treatment was superior to radiotherapy alone in 5-year survival rates.

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