Primary Radiotherapy Treatment Results of Maxillary Sinus Squamous Cell Carcinoma

Chih-Chiech Hsu, Louis Tak Lui, Na-Na Chung, Lai-Lei Ting, Wen-Yi Shau

Research output: Contribution to journalArticle

Abstract

Purpose: Evaluating 5-year survival rates of maxillary sinus squamous cell carcinoma treated by different methods.Materials and Methods: From 1997 to 1991, 61 patients of maxillary sinus squamous cell carcinoma were included in our study. There were 11 patients with T3 (18%) disease and 50 patients with T4 (82%) disease. Eighteen patients (29.5%) were treated by radiotherapy alone (RT), 32 patients (52.5%) by combined surgery and radiotherapy (SRT) and 11 patients (18.0%) by combined radiotherapy with intra-arterial 5-FU infusion chemotherapy and antrostomy drainage (CRT).Results: Five-year survival rates were 5.6%, 34.4% and 54.5% in RT, SRT and CRT groups, respectively. Statistical significant difference (p<0.05) of survival rates was noted. Regional neck nodal metastasis at initial diagnosis carried significant worse survival results than initial NO state (7.1% vs. 36.2%, p=0.0003). Multivariate analysis revealed that treatment methods, sex and N stages significantly influenced the 5-year survival rate.Conclusion: Combined treatment was superior to radiotherapy alone in 5-year survival rates.
Translated title of the contribution上頷竇扁平細胞癌之放射治療結果
Original languageEnglish
Pages (from-to)163-170
Number of pages8
Journal放射治療與腫瘤學
Volume5
Issue number3
DOIs
Publication statusPublished - 1998
Externally publishedYes

Keywords

  • Radiotherapy
  • Combined treatment
  • Maxillary sinus
  • Squamous cell carcinoma

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