Primary Radiotherapy Treatment Results of Maxillary Sinus Squamous Cell Carcinoma

Chih-Chiech Hsu, Louis Tak Lui, Na-Na Chung, Lai-Lei Ting, Wen-Yi Shau

Research output: Contribution to journalArticle

Abstract

Purpose: Evaluating 5-year survival rates of maxillary sinus squamous cell carcinoma treated by different methods.Materials and Methods: From 1997 to 1991, 61 patients of maxillary sinus squamous cell carcinoma were included in our study. There were 11 patients with T3 (18%) disease and 50 patients with T4 (82%) disease. Eighteen patients (29.5%) were treated by radiotherapy alone (RT), 32 patients (52.5%) by combined surgery and radiotherapy (SRT) and 11 patients (18.0%) by combined radiotherapy with intra-arterial 5-FU infusion chemotherapy and antrostomy drainage (CRT).Results: Five-year survival rates were 5.6%, 34.4% and 54.5% in RT, SRT and CRT groups, respectively. Statistical significant difference (p<0.05) of survival rates was noted. Regional neck nodal metastasis at initial diagnosis carried significant worse survival results than initial NO state (7.1% vs. 36.2%, p=0.0003). Multivariate analysis revealed that treatment methods, sex and N stages significantly influenced the 5-year survival rate.Conclusion: Combined treatment was superior to radiotherapy alone in 5-year survival rates.
Original languageEnglish
Pages (from-to)163-170
Number of pages8
Journal放射治療與腫瘤學
Volume5
Issue number3
DOIs
Publication statusPublished - 1998
Externally publishedYes

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Maxillary Sinus
Squamous Cell Carcinoma
Radiotherapy
Survival Rate
Therapeutics
Fluorouracil
Drainage
Neck
Multivariate Analysis
Neoplasm Metastasis
Drug Therapy
Survival

Keywords

  • Radiotherapy
  • Combined treatment
  • Maxillary sinus
  • Squamous cell carcinoma

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Primary Radiotherapy Treatment Results of Maxillary Sinus Squamous Cell Carcinoma. / Hsu, Chih-Chiech; Lui, Louis Tak; Chung, Na-Na; Ting, Lai-Lei; Shau, Wen-Yi.

In: 放射治療與腫瘤學, Vol. 5, No. 3, 1998, p. 163-170.

Research output: Contribution to journalArticle

Hsu, Chih-Chiech ; Lui, Louis Tak ; Chung, Na-Na ; Ting, Lai-Lei ; Shau, Wen-Yi. / Primary Radiotherapy Treatment Results of Maxillary Sinus Squamous Cell Carcinoma. In: 放射治療與腫瘤學. 1998 ; Vol. 5, No. 3. pp. 163-170.
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abstract = "Purpose: Evaluating 5-year survival rates of maxillary sinus squamous cell carcinoma treated by different methods.Materials and Methods: From 1997 to 1991, 61 patients of maxillary sinus squamous cell carcinoma were included in our study. There were 11 patients with T3 (18{\%}) disease and 50 patients with T4 (82{\%}) disease. Eighteen patients (29.5{\%}) were treated by radiotherapy alone (RT), 32 patients (52.5{\%}) by combined surgery and radiotherapy (SRT) and 11 patients (18.0{\%}) by combined radiotherapy with intra-arterial 5-FU infusion chemotherapy and antrostomy drainage (CRT).Results: Five-year survival rates were 5.6{\%}, 34.4{\%} and 54.5{\%} in RT, SRT and CRT groups, respectively. Statistical significant difference (p<0.05) of survival rates was noted. Regional neck nodal metastasis at initial diagnosis carried significant worse survival results than initial NO state (7.1{\%} vs. 36.2{\%}, p=0.0003). Multivariate analysis revealed that treatment methods, sex and N stages significantly influenced the 5-year survival rate.Conclusion: Combined treatment was superior to radiotherapy alone in 5-year survival rates.",
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