Primary non-Hodgkin's lymphoma of the spine

A case report

Yung Cheng Wang, Jing Shan Huang, Chin Ming Jeng, Shih Hung Huang, Ching Huei Kung, Chau Ying Wu, Wen Yu Lee, Yung Chien Huang

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 16-year-old male patient abruptly developed weakness and tremor of the right leg and was unable to stand up two months ago. Lumbar spine radiograph revealed a suspicious, purely osteolytic lesion at the vertebral body of L5. No pathologic fracture was noted. The lesion showed permeative, purely osteolytic bone destruction of the vertebral body of L5 on computed tomography (CT) image. An epidural soft tissue mass at the corresponding level with ventral compression on the thecal sac was also noted. Magnetic resonance (MR) imaging of the lesion was hypointense on TI-weighted images and hyperintense on T2-weighted images. Good contrast enhancement was found on Gadolinium enhanced T1-weighted images. Bone marrow aspiration of the sternum revealed no abnormalities. Tumor was removed by operation and histologically proved to be large cell lymphoma with massive necrosis. Primary non-Hodgkin's lymphoma of bone is rare, especially in spine. To our knowledge, this is the first report of the MR and CT findings of primary non-Hodgkin's lymphoma of the spine in a young patient.

Original languageEnglish
Pages (from-to)261-264
Number of pages4
JournalChinese Journal of Radiology
Volume26
Issue number6
Publication statusPublished - Dec 1 2001
Externally publishedYes

Fingerprint

Non-Hodgkin's Lymphoma
Spine
Tomography
Bone and Bones
Spontaneous Fractures
Sternum
Gadolinium
Tremor
Lymphoma
Leg
Necrosis
Magnetic Resonance Spectroscopy
Bone Marrow
Magnetic Resonance Imaging
Neoplasms

Keywords

  • Non-Hodgkin's lymphoma
  • Paravertebral soft tissue
  • Spine
  • Vertebral body

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Wang, Y. C., Huang, J. S., Jeng, C. M., Huang, S. H., Kung, C. H., Wu, C. Y., ... Huang, Y. C. (2001). Primary non-Hodgkin's lymphoma of the spine: A case report. Chinese Journal of Radiology, 26(6), 261-264.

Primary non-Hodgkin's lymphoma of the spine : A case report. / Wang, Yung Cheng; Huang, Jing Shan; Jeng, Chin Ming; Huang, Shih Hung; Kung, Ching Huei; Wu, Chau Ying; Lee, Wen Yu; Huang, Yung Chien.

In: Chinese Journal of Radiology, Vol. 26, No. 6, 01.12.2001, p. 261-264.

Research output: Contribution to journalArticle

Wang, YC, Huang, JS, Jeng, CM, Huang, SH, Kung, CH, Wu, CY, Lee, WY & Huang, YC 2001, 'Primary non-Hodgkin's lymphoma of the spine: A case report', Chinese Journal of Radiology, vol. 26, no. 6, pp. 261-264.
Wang YC, Huang JS, Jeng CM, Huang SH, Kung CH, Wu CY et al. Primary non-Hodgkin's lymphoma of the spine: A case report. Chinese Journal of Radiology. 2001 Dec 1;26(6):261-264.
Wang, Yung Cheng ; Huang, Jing Shan ; Jeng, Chin Ming ; Huang, Shih Hung ; Kung, Ching Huei ; Wu, Chau Ying ; Lee, Wen Yu ; Huang, Yung Chien. / Primary non-Hodgkin's lymphoma of the spine : A case report. In: Chinese Journal of Radiology. 2001 ; Vol. 26, No. 6. pp. 261-264.
@article{34432e3b4ec34f19b56329806aa82826,
title = "Primary non-Hodgkin's lymphoma of the spine: A case report",
abstract = "A 16-year-old male patient abruptly developed weakness and tremor of the right leg and was unable to stand up two months ago. Lumbar spine radiograph revealed a suspicious, purely osteolytic lesion at the vertebral body of L5. No pathologic fracture was noted. The lesion showed permeative, purely osteolytic bone destruction of the vertebral body of L5 on computed tomography (CT) image. An epidural soft tissue mass at the corresponding level with ventral compression on the thecal sac was also noted. Magnetic resonance (MR) imaging of the lesion was hypointense on TI-weighted images and hyperintense on T2-weighted images. Good contrast enhancement was found on Gadolinium enhanced T1-weighted images. Bone marrow aspiration of the sternum revealed no abnormalities. Tumor was removed by operation and histologically proved to be large cell lymphoma with massive necrosis. Primary non-Hodgkin's lymphoma of bone is rare, especially in spine. To our knowledge, this is the first report of the MR and CT findings of primary non-Hodgkin's lymphoma of the spine in a young patient.",
keywords = "Non-Hodgkin's lymphoma, Paravertebral soft tissue, Spine, Vertebral body",
author = "Wang, {Yung Cheng} and Huang, {Jing Shan} and Jeng, {Chin Ming} and Huang, {Shih Hung} and Kung, {Ching Huei} and Wu, {Chau Ying} and Lee, {Wen Yu} and Huang, {Yung Chien}",
year = "2001",
month = "12",
day = "1",
language = "English",
volume = "26",
pages = "261--264",
journal = "Chinese Journal of Radiology",
issn = "1018-8940",
publisher = "中華民國放射線醫學會",
number = "6",

}

TY - JOUR

T1 - Primary non-Hodgkin's lymphoma of the spine

T2 - A case report

AU - Wang, Yung Cheng

AU - Huang, Jing Shan

AU - Jeng, Chin Ming

AU - Huang, Shih Hung

AU - Kung, Ching Huei

AU - Wu, Chau Ying

AU - Lee, Wen Yu

AU - Huang, Yung Chien

PY - 2001/12/1

Y1 - 2001/12/1

N2 - A 16-year-old male patient abruptly developed weakness and tremor of the right leg and was unable to stand up two months ago. Lumbar spine radiograph revealed a suspicious, purely osteolytic lesion at the vertebral body of L5. No pathologic fracture was noted. The lesion showed permeative, purely osteolytic bone destruction of the vertebral body of L5 on computed tomography (CT) image. An epidural soft tissue mass at the corresponding level with ventral compression on the thecal sac was also noted. Magnetic resonance (MR) imaging of the lesion was hypointense on TI-weighted images and hyperintense on T2-weighted images. Good contrast enhancement was found on Gadolinium enhanced T1-weighted images. Bone marrow aspiration of the sternum revealed no abnormalities. Tumor was removed by operation and histologically proved to be large cell lymphoma with massive necrosis. Primary non-Hodgkin's lymphoma of bone is rare, especially in spine. To our knowledge, this is the first report of the MR and CT findings of primary non-Hodgkin's lymphoma of the spine in a young patient.

AB - A 16-year-old male patient abruptly developed weakness and tremor of the right leg and was unable to stand up two months ago. Lumbar spine radiograph revealed a suspicious, purely osteolytic lesion at the vertebral body of L5. No pathologic fracture was noted. The lesion showed permeative, purely osteolytic bone destruction of the vertebral body of L5 on computed tomography (CT) image. An epidural soft tissue mass at the corresponding level with ventral compression on the thecal sac was also noted. Magnetic resonance (MR) imaging of the lesion was hypointense on TI-weighted images and hyperintense on T2-weighted images. Good contrast enhancement was found on Gadolinium enhanced T1-weighted images. Bone marrow aspiration of the sternum revealed no abnormalities. Tumor was removed by operation and histologically proved to be large cell lymphoma with massive necrosis. Primary non-Hodgkin's lymphoma of bone is rare, especially in spine. To our knowledge, this is the first report of the MR and CT findings of primary non-Hodgkin's lymphoma of the spine in a young patient.

KW - Non-Hodgkin's lymphoma

KW - Paravertebral soft tissue

KW - Spine

KW - Vertebral body

UR - http://www.scopus.com/inward/record.url?scp=0035722090&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035722090&partnerID=8YFLogxK

M3 - Article

VL - 26

SP - 261

EP - 264

JO - Chinese Journal of Radiology

JF - Chinese Journal of Radiology

SN - 1018-8940

IS - 6

ER -