Primary liver abscess due to Klebsiella pneumoniae in Taiwan

Jen Hsien Wang, Yung Ching Liu, Susan Shin Jung Lee, Muh Yong Yen, Yao Shen Chen, Jao Hsien Wang, Shuc Ren Wann, Hsi Hsun Lin

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407 Citations (Scopus)

Abstract

Pyogenic liver abscess is an uncommon complication of intra-abdominal or biliary tract infection and is usually a polymicrobial infection associated with high mortality and high rates of relapse. However, over the past 15 years, we have observed a new clinical syndrome in Taiwan: liver abscesses caused by a single microorganism, Klebsiella pneumoniae. We reviewed 182 cases of pyogenic river abscess during the period September 1990 to June 1996; 160 of these cases were caused by K. pneumoniae alone, and 22 were polymicrobial. When patients with K. pneumoniae liver abscess were compared with those who had polymicrobial liver abscess, we found higher incidences of diabetes or glucose intolerance (75% vs. 4.5%) and metastatic infections (11.9% vs. 0) and lower rates of intra-abdominal abnormalities (0.6% vs. 95.5%), mortality (11.3% vs. 41%), and relapse (4.4% vs. 41%) in the former group. Liver abscess caused by K. pneumoniae is a new clinical syndrome that has emerged as an important infectious complication in diabetic patients in Taiwan.

Original languageEnglish
Pages (from-to)1434-1438
Number of pages5
JournalClinical Infectious Diseases
Volume26
Issue number6
Publication statusPublished - 1998
Externally publishedYes

ASJC Scopus subject areas

  • Immunology

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    Wang, J. H., Liu, Y. C., Lee, S. S. J., Yen, M. Y., Chen, Y. S., Wang, J. H., Wann, S. R., & Lin, H. H. (1998). Primary liver abscess due to Klebsiella pneumoniae in Taiwan. Clinical Infectious Diseases, 26(6), 1434-1438.