Primary liver abscess due to Klebsiella pneumoniae in Taiwan

Jen Hsien Wang, Yung Ching Liu, Susan Shin Jung Lee, Muh Yong Yen, Yao Shen Chen, Jao Hsien Wang, Shuc Ren Wann, Hsi Hsun Lin

Research output: Contribution to journalArticle

391 Citations (Scopus)

Abstract

Pyogenic liver abscess is an uncommon complication of intra-abdominal or biliary tract infection and is usually a polymicrobial infection associated with high mortality and high rates of relapse. However, over the past 15 years, we have observed a new clinical syndrome in Taiwan: liver abscesses caused by a single microorganism, Klebsiella pneumoniae. We reviewed 182 cases of pyogenic river abscess during the period September 1990 to June 1996; 160 of these cases were caused by K. pneumoniae alone, and 22 were polymicrobial. When patients with K. pneumoniae liver abscess were compared with those who had polymicrobial liver abscess, we found higher incidences of diabetes or glucose intolerance (75% vs. 4.5%) and metastatic infections (11.9% vs. 0) and lower rates of intra-abdominal abnormalities (0.6% vs. 95.5%), mortality (11.3% vs. 41%), and relapse (4.4% vs. 41%) in the former group. Liver abscess caused by K. pneumoniae is a new clinical syndrome that has emerged as an important infectious complication in diabetic patients in Taiwan.

Original languageEnglish
Pages (from-to)1434-1438
Number of pages5
JournalClinical Infectious Diseases
Volume26
Issue number6
Publication statusPublished - 1998
Externally publishedYes

Fingerprint

Liver Abscess
Klebsiella pneumoniae
Taiwan
Pyogenic Liver Abscess
Recurrence
Glucose Intolerance
Mortality
Biliary Tract
Diabetes Complications
Infection
Coinfection
Rivers
Abscess
Incidence

ASJC Scopus subject areas

  • Immunology

Cite this

Wang, J. H., Liu, Y. C., Lee, S. S. J., Yen, M. Y., Chen, Y. S., Wang, J. H., ... Lin, H. H. (1998). Primary liver abscess due to Klebsiella pneumoniae in Taiwan. Clinical Infectious Diseases, 26(6), 1434-1438.

Primary liver abscess due to Klebsiella pneumoniae in Taiwan. / Wang, Jen Hsien; Liu, Yung Ching; Lee, Susan Shin Jung; Yen, Muh Yong; Chen, Yao Shen; Wang, Jao Hsien; Wann, Shuc Ren; Lin, Hsi Hsun.

In: Clinical Infectious Diseases, Vol. 26, No. 6, 1998, p. 1434-1438.

Research output: Contribution to journalArticle

Wang, JH, Liu, YC, Lee, SSJ, Yen, MY, Chen, YS, Wang, JH, Wann, SR & Lin, HH 1998, 'Primary liver abscess due to Klebsiella pneumoniae in Taiwan', Clinical Infectious Diseases, vol. 26, no. 6, pp. 1434-1438.
Wang JH, Liu YC, Lee SSJ, Yen MY, Chen YS, Wang JH et al. Primary liver abscess due to Klebsiella pneumoniae in Taiwan. Clinical Infectious Diseases. 1998;26(6):1434-1438.
Wang, Jen Hsien ; Liu, Yung Ching ; Lee, Susan Shin Jung ; Yen, Muh Yong ; Chen, Yao Shen ; Wang, Jao Hsien ; Wann, Shuc Ren ; Lin, Hsi Hsun. / Primary liver abscess due to Klebsiella pneumoniae in Taiwan. In: Clinical Infectious Diseases. 1998 ; Vol. 26, No. 6. pp. 1434-1438.
@article{ee894a198333485a8b5adb5e81ebe72f,
title = "Primary liver abscess due to Klebsiella pneumoniae in Taiwan",
abstract = "Pyogenic liver abscess is an uncommon complication of intra-abdominal or biliary tract infection and is usually a polymicrobial infection associated with high mortality and high rates of relapse. However, over the past 15 years, we have observed a new clinical syndrome in Taiwan: liver abscesses caused by a single microorganism, Klebsiella pneumoniae. We reviewed 182 cases of pyogenic river abscess during the period September 1990 to June 1996; 160 of these cases were caused by K. pneumoniae alone, and 22 were polymicrobial. When patients with K. pneumoniae liver abscess were compared with those who had polymicrobial liver abscess, we found higher incidences of diabetes or glucose intolerance (75{\%} vs. 4.5{\%}) and metastatic infections (11.9{\%} vs. 0) and lower rates of intra-abdominal abnormalities (0.6{\%} vs. 95.5{\%}), mortality (11.3{\%} vs. 41{\%}), and relapse (4.4{\%} vs. 41{\%}) in the former group. Liver abscess caused by K. pneumoniae is a new clinical syndrome that has emerged as an important infectious complication in diabetic patients in Taiwan.",
author = "Wang, {Jen Hsien} and Liu, {Yung Ching} and Lee, {Susan Shin Jung} and Yen, {Muh Yong} and Chen, {Yao Shen} and Wang, {Jao Hsien} and Wann, {Shuc Ren} and Lin, {Hsi Hsun}",
year = "1998",
language = "English",
volume = "26",
pages = "1434--1438",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",
number = "6",

}

TY - JOUR

T1 - Primary liver abscess due to Klebsiella pneumoniae in Taiwan

AU - Wang, Jen Hsien

AU - Liu, Yung Ching

AU - Lee, Susan Shin Jung

AU - Yen, Muh Yong

AU - Chen, Yao Shen

AU - Wang, Jao Hsien

AU - Wann, Shuc Ren

AU - Lin, Hsi Hsun

PY - 1998

Y1 - 1998

N2 - Pyogenic liver abscess is an uncommon complication of intra-abdominal or biliary tract infection and is usually a polymicrobial infection associated with high mortality and high rates of relapse. However, over the past 15 years, we have observed a new clinical syndrome in Taiwan: liver abscesses caused by a single microorganism, Klebsiella pneumoniae. We reviewed 182 cases of pyogenic river abscess during the period September 1990 to June 1996; 160 of these cases were caused by K. pneumoniae alone, and 22 were polymicrobial. When patients with K. pneumoniae liver abscess were compared with those who had polymicrobial liver abscess, we found higher incidences of diabetes or glucose intolerance (75% vs. 4.5%) and metastatic infections (11.9% vs. 0) and lower rates of intra-abdominal abnormalities (0.6% vs. 95.5%), mortality (11.3% vs. 41%), and relapse (4.4% vs. 41%) in the former group. Liver abscess caused by K. pneumoniae is a new clinical syndrome that has emerged as an important infectious complication in diabetic patients in Taiwan.

AB - Pyogenic liver abscess is an uncommon complication of intra-abdominal or biliary tract infection and is usually a polymicrobial infection associated with high mortality and high rates of relapse. However, over the past 15 years, we have observed a new clinical syndrome in Taiwan: liver abscesses caused by a single microorganism, Klebsiella pneumoniae. We reviewed 182 cases of pyogenic river abscess during the period September 1990 to June 1996; 160 of these cases were caused by K. pneumoniae alone, and 22 were polymicrobial. When patients with K. pneumoniae liver abscess were compared with those who had polymicrobial liver abscess, we found higher incidences of diabetes or glucose intolerance (75% vs. 4.5%) and metastatic infections (11.9% vs. 0) and lower rates of intra-abdominal abnormalities (0.6% vs. 95.5%), mortality (11.3% vs. 41%), and relapse (4.4% vs. 41%) in the former group. Liver abscess caused by K. pneumoniae is a new clinical syndrome that has emerged as an important infectious complication in diabetic patients in Taiwan.

UR - http://www.scopus.com/inward/record.url?scp=0031866509&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031866509&partnerID=8YFLogxK

M3 - Article

C2 - 9636876

AN - SCOPUS:0031866509

VL - 26

SP - 1434

EP - 1438

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

SN - 1058-4838

IS - 6

ER -