Abstract
Eleven patients with primary central nervous system lymphoma (PCNSL) proven with biopsy between January 1991 and September 1995 were analysed according to the location of lesions, pathological studies, treatment and outcome. The ages of these patients ranged from 25 to 74 years with an average of 51.4 years. The male to female sex ratio was 6 to 5. The most frequent sites of lesions were frontal lobes. One patient had only leptomeningeal involvement. All intracranial PCNSL in this report arose from B cells; the leptomeningeal PCNSL case was the only one which arose from T cells. All patients received chemotherapy with or without radiotherapy, except two patients who did not receive any treatment. The results of treatment were generally poor. The survival time of patients who died ranged from 2.5 months to 45 months with a median of about 12.5 months. If a combined treatment is to be considered, the possibility of complications such as leucoencephalopathy should be taken in account.
| Original language | English |
|---|---|
| Pages (from-to) | 409-412 |
| Number of pages | 4 |
| Journal | Journal of Clinical Neuroscience |
| Volume | 5 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Jan 1 1998 |
| Externally published | Yes |
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Keywords
- Central nervous system
- Chemotherapy
- Lymphoma
- Radiotherapy
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
- Physiology (medical)
Cite this
Primary central nervous system lymphoma : A retrospective study. / Tseng, Ming Yuan; Tu, Yong Kwang; Shun, Chia Tung.
In: Journal of Clinical Neuroscience, Vol. 5, No. 4, 01.01.1998, p. 409-412.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Primary central nervous system lymphoma
T2 - A retrospective study
AU - Tseng, Ming Yuan
AU - Tu, Yong Kwang
AU - Shun, Chia Tung
PY - 1998/1/1
Y1 - 1998/1/1
N2 - Eleven patients with primary central nervous system lymphoma (PCNSL) proven with biopsy between January 1991 and September 1995 were analysed according to the location of lesions, pathological studies, treatment and outcome. The ages of these patients ranged from 25 to 74 years with an average of 51.4 years. The male to female sex ratio was 6 to 5. The most frequent sites of lesions were frontal lobes. One patient had only leptomeningeal involvement. All intracranial PCNSL in this report arose from B cells; the leptomeningeal PCNSL case was the only one which arose from T cells. All patients received chemotherapy with or without radiotherapy, except two patients who did not receive any treatment. The results of treatment were generally poor. The survival time of patients who died ranged from 2.5 months to 45 months with a median of about 12.5 months. If a combined treatment is to be considered, the possibility of complications such as leucoencephalopathy should be taken in account.
AB - Eleven patients with primary central nervous system lymphoma (PCNSL) proven with biopsy between January 1991 and September 1995 were analysed according to the location of lesions, pathological studies, treatment and outcome. The ages of these patients ranged from 25 to 74 years with an average of 51.4 years. The male to female sex ratio was 6 to 5. The most frequent sites of lesions were frontal lobes. One patient had only leptomeningeal involvement. All intracranial PCNSL in this report arose from B cells; the leptomeningeal PCNSL case was the only one which arose from T cells. All patients received chemotherapy with or without radiotherapy, except two patients who did not receive any treatment. The results of treatment were generally poor. The survival time of patients who died ranged from 2.5 months to 45 months with a median of about 12.5 months. If a combined treatment is to be considered, the possibility of complications such as leucoencephalopathy should be taken in account.
KW - Central nervous system
KW - Chemotherapy
KW - Lymphoma
KW - Radiotherapy
UR - http://www.scopus.com/inward/record.url?scp=11544361458&partnerID=8YFLogxK
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U2 - 10.1016/S0967-5868(98)90273-9
DO - 10.1016/S0967-5868(98)90273-9
M3 - Article
VL - 5
SP - 409
EP - 412
JO - Journal of Clinical Neuroscience
JF - Journal of Clinical Neuroscience
SN - 0967-5868
IS - 4
ER -